Tagatose
Description
Type: small molecule
Groups: investigational
Indication: Intended for use as a therapeutic adjunct in the treatment of type II diabetes.
Accession Number: DB04936 ( DB04936)
Description: Tagatose is a functional sweetener. It is a naturally occurring monosaccharide, specifically a hexose. It is often found in dairy products, and is very similar in texture to sucrose (table sugar) and is 92% as sweet, but with only 38% of the calories. It is approved as a food additive as a low calorie sweetener. Additionally, it is under investigation by Spherix for the treatment of obesity and type II diabetes.
Structure:
Prescription Products: Not Available
Generic Prescription Products: Not Available
Over the Counter Products: Not Available
International Brands
- No Brands
Brand Names
- No Brands
Brand Mixtures
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Categories
- Iron Chelating Agents
Pharmacology
Pharmacodynamics: Not Available
Mechanism of action: he steps in the metabolism of tagatose are identical to those for fructose or fruit sugar but tagatose is incompletely absorbed. Only 15-20 percent of tagatose is absorbed in the small intestine. The major part of ingested tagatose is fermented in the colon by indigenous microflora, resulting in the production of short-chain fatty acids. The short chain fatty acids are absorbed almost completely and metabolized.
Absorption: Only 15-20 percent of tagatose is absorbed in the small intestine.
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half life: Not Available
Clearance: Not Available
Toxicity: Not Available
Affected organisms
- Not Available
SNP Mediated Adverse Drug Reactions
- Not Available
Pharmacoeconomics
- Not Available
Packagers:
- Not Available
Dosage forms
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Patents
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Interactions
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Food Interactions:
- Not Available
Taxonomy
Super Class: Not Available
Class: Not Available
Sub Class: Not Available
Direct Parent: Not Available
Alternative Parents:
- 1,2-diols
- Acyloins
- Alpha-hydroxy ketones
- Beta ketoaldehydes
- Beta-hydroxy ketones
- Hydrocarbon derivatives
- Primary alcohols
- Secondary alcohols
substituent:
- 1,2-diol
- Acyloin
- Alcohol
- Aliphatic acyclic compound
- Alpha-hydroxy ketone
- Beta-hydroxy ketone
- Beta-ketoaldehyde
- Carbonyl group
- Hydrocarbon derivative
- Ketone
- Monosaccharide
- Polyol
- Primary alcohol
- Secondary alcohol
References
General Reference: # Donner TW, Wilber JF, Ostrowski D: D-tagatose, a novel hexose: acute effects on carbohydrate tolerance in subjects with and without type 2 diabetes. Diabetes Obes Metab. 1999 Sep;1(5):285-91. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/11225640
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ATC Codes:
- Not Available
AHFS Codes:
- Not Available
MSDS: Download