Detail

TAFA-93

Description

Name: TAFA-93
Type: small molecule
Groups: investigational
Indication: Investigated for use/treatment in transplant (rejection).
Accession Number: DB05887 ( DB05887)
Description: TAFA93 is a novel prodrug of the mTOR inhibitor rapamycin which has successfully completed Phase 1 clinical development. mTOR inhibitors are currently used in the prevention of organ rejection in transplantation, the treatment of autoimmune and oncological diseases, and as a component of coated stents for the treatment of coronary artery disease.
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Prescription Products: Not Available
Generic Prescription Products: Not Available
Over the Counter Products: Not Available
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Pharmacology

Indication: Investigated for use/treatment in transplant (rejection).
Pharmacodynamics: Not Available
Mechanism of action: TAFA-93 has distinct mechanism of action than calcineurin inhibitors such as ISA247, Isotechnika’s lead drug. It has the pontential to be administered as a complementary therapy along with ISA247 in the prevention of organ rejection after transplantation.
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half life: Not Available
Clearance: Not Available
Toxicity: Not Available
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Pharmacoeconomics

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Taxonomy

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References

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MSDS: Download
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