Detail

T-1249

Description

Name: T-1249
Type: small molecule
Groups: investigational
Indication: Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection.
Accession Number: DB05413 ( DB05413)
Description: T-1249 is the first members of a new class of anti-HIV drugs which is also called fusion inhibitors. It has received fast track designation from the FDA and is in Phase I/II clinical testing.
Structure:
Prescription Products: Not Available
Generic Prescription Products: Not Available
Over the Counter Products: Not Available
International Brands
  • No Brands

Brand Names
  • No Brands

Brand Mixtures
Brand NameIngredients

Categories
  • No Category

Pharmacology

Indication: Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection.
Pharmacodynamics: Not Available
Mechanism of action: T-1249 binds to a slightly different region of the HIV virus than Fuzeon (enfuvirtide). As a result,it exhibits activity against Fuzeon-resistant viruses. T-1249 is designed to block fusion of HIV with host cells before the virus enters the cell and begins its replication process.
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half life: Not Available
Clearance: Not Available
Toxicity: Not Available
Affected organisms
  • Not Available

SNP Mediated Adverse Drug Reactions
  • Not Available

Pharmacoeconomics

Manufacturers:
  • Not Available

Packagers:
  • Not Available

Dosage forms
FormRouteStrength

Prices
Unit descriptionCostUnit

Patents
CountryPatent NumberApprovedExpires (estimated)

Interactions

Drug Interactions
DrugInteraction

Food Interactions:
  • Not Available

Taxonomy

Kingdom: Organic compounds
Super Class: Not Available
Class: Not Available
Sub Class: Not Available
Direct Parent: Not Available
Alternative Parents:
  • Acetamides
  • Alpha amino acid amides
  • Amino fatty acids
  • Amphetamines and derivatives
  • Azacyclic compounds
  • Carbonyl compounds
  • Carboxylic acids
  • Heteroaromatic compounds
  • Hydrocarbon derivatives
  • Indoles
  • Monoalkylamines
  • N-acyl amines
  • N-acyl-alpha amino acids and derivatives
  • Peptides
  • Phenols and derivatives
  • Phenylpropylamines
  • Primary alcohols
  • Primary carboxylic acid amides
  • Secondary alcohols
  • Secondary carboxylic acid amides
  • Substituted pyrroles
  • Tryptamines and derivatives

substituent:
  • Acetamide
  • Alcohol
  • Alpha peptide
  • Alpha-amino acid amide
  • Amine
  • Amino fatty acid
  • Amphetamine or derivatives
  • Aromatic heteropolycyclic compound
  • Azacycle
  • Benzenoid
  • Carbonyl group
  • Carboxamide group
  • Carboxylic acid
  • Carboxylic acid amide
  • Carboxylic acid derivative
  • Fatty acyl
  • Fatty amide
  • Heteroaromatic compound
  • Hydrocarbon derivative
  • Indole
  • Indole or derivatives
  • Monocyclic benzene moiety
  • N-acyl-alpha amino acid or derivatives
  • N-acyl-amine
  • N-substituted-alpha-amino acid
  • Organoheterocyclic compound
  • Organonitrogen compound
  • Organooxygen compound
  • Phenol
  • Phenylpropylamine
  • Polypeptide
  • Primary alcohol
  • Primary aliphatic amine
  • Primary amine
  • Primary carboxylic acid amide
  • Pyrrole
  • Secondary alcohol
  • Secondary carboxylic acid amide
  • Substituted pyrrole
  • Triptan

References

Synthesis Reference: Not Available
General Reference: Not Available
External Links:
ResourceLink

ATC Codes:
  • Not Available

AHFS Codes:
  • Not Available

MSDS: Download
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