Name: Gadoteric acid

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Type: small molecule

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Groups: approved

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Indication: Not Available

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Accession Number: DB09132 ( DB09132)

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Description: Gadoteric acid is a macrocycle-structured gadolinium-based MRI contrast agent. It consists of the organic acid DOTA as a chelating agent, and gadolinium (Gd3+), and is used in form of the meglumine salt. The drug is approved and used in a number of countries worldwide. It is used to assist imaging of blood vessels and of inflamed or diseased tissue where the blood vessels become 'leaky'. It is often used when viewing intracranial lesions with abnormal vascularity or abnormalities in the blood–brain barrier. Its paramagnetic property reduces the T1 relaxation time (and to some extent the T2 and T2* relaxation times) in NMR, which is the source of its clinical utility.

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Structure:

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Prescription Products:

Name	Dosage	Strength	Route	Marketing Start	Marketing End	Country
Dotarem	injection	376.9 mg/mL	intravenous	20-03-2013	01-01-1970	US

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Generic Prescription Products: Not Available

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Over the Counter Products: Not Available

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International Brands

• No Brands

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Brand Names

• No Brands

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Brand Mixtures

Brand Name	Ingredients
Dotarem	Gadoteric acid

Brand Name	Ingredients
Dotarem	Gadoteric acid

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Categories

• No Category

Indication: Not Available

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Pharmacodynamics: Not Available

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Mechanism of action: Not Available

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Absorption: Not Available

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Volume of distribution: Not Available

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Protein binding: Not Available

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Metabolism: Not Available

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Route of elimination: Not Available

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Half life: Not Available

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Clearance: Not Available

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Toxicity: Not Available

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Affected organisms

• Not Available

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SNP Mediated Adverse Drug Reactions

• Not Available

Manufacturers:

• Not Available

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Packagers:

• Not Available

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Dosage forms

Form	Route	Strength
Injection	intravenous	376.9 mg/mL

Form	Route	Strength
Injection	intravenous	376.9 mg/mL

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Prices

Unit description	Cost	Unit

Unit description	Cost	Unit

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Patents

Country	Patent Number	Approved	Expires (estimated)

Drug Interactions

Drug	Interaction

Drug	Interaction

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Food Interactions:

• Not Available

Kingdom: Not Available

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Super Class: Not Available

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Class: Not Available

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Sub Class: Not Available

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Direct Parent: Not Available

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Alternative Parents:

• Not Available

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substituent:

• Not Available

Synthesis Reference: Not Available

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General Reference: Not Available

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External Links:

Resource	Link
Drugs.com	http://www.drugs.com/international/gadoteric-acid.html

Resource	Link
Drugs.com	http://www.drugs.com/international/gadoteric-acid.html

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ATC Codes:

• Array

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AHFS Codes:

• Not Available

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MSDS: Download