Detail

Gaboxadol

Description

Name: Gaboxadol
Type: small molecule
Groups: investigational
Indication: Investigated for use/treatment in sleep disorders and insomnia.
Accession Number: DB06554 ( DB06554)
Description: Gaboxadol also known as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) is an experimental sleep aid drug developed by Lundbeck and Merck. In March, 2007, Merck and H. Lundbeck cancelled work on the drug, citing safety concerns and the failure of an efficacy trial. It acts on the GABA system, but possibly in a different way from benzodiazepines, nonbenzodiazepines and barbiturates - (Valium, Sodium Pentothal, Ambien etc.). Lundbeck states that gaboxadol also increases deep sleep (stage 4). It is, however, not reinforcing like benzodiazepines are. [Wikipedia]
Structure:
Prescription Products: Not Available
Generic Prescription Products: Not Available
Over the Counter Products: Not Available
International Brands
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Brand Names
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Brand Mixtures
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Categories
  • No Category

Pharmacology

Indication: Investigated for use/treatment in sleep disorders and insomnia.
Pharmacodynamics: Not Available
Mechanism of action: Not Available
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half life: Not Available
Clearance: Not Available
Toxicity: Not Available
Affected organisms
  • Not Available

SNP Mediated Adverse Drug Reactions
  • Not Available

Pharmacoeconomics

Manufacturers:
  • Not Available

Packagers:
  • Not Available

Dosage forms
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Patents
CountryPatent NumberApprovedExpires (estimated)

Interactions

Drug Interactions
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Food Interactions:
  • Not Available

Taxonomy

Kingdom: Organic compounds
Super Class: Not Available
Class: Not Available
Sub Class: Not Available
Direct Parent: Not Available
Alternative Parents:
  • Azacyclic compounds
  • Dialkylamines
  • Heteroaromatic compounds
  • Hydrocarbon derivatives
  • Isoxazoles
  • Lactams
  • Organooxygen compounds
  • Oxacyclic compounds
  • Oxazoles

substituent:
  • Aralkylamine
  • Aromatic heteropolycyclic compound
  • Azacycle
  • Azole
  • Heteroaromatic compound
  • Hydrocarbon derivative
  • Isoxazole
  • Lactam
  • Organoheterocyclic compound
  • Organooxygen compound
  • Oxacycle
  • Oxazole
  • Secondary aliphatic amine
  • Secondary amine

References

Synthesis Reference: Not Available
General Reference: Not Available
External Links:
ResourceLink

ATC Codes:
  • Not Available

AHFS Codes:
  • Not Available

MSDS: Download
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