Name: Gaboxadol

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Type: small molecule

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Groups: investigational

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Indication: Investigated for use/treatment in sleep disorders and insomnia.

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Accession Number: DB06554 ( DB06554)

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Description: Gaboxadol also known as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) is an experimental sleep aid drug developed by Lundbeck and Merck. In March, 2007, Merck and H. Lundbeck cancelled work on the drug, citing safety concerns and the failure of an efficacy trial. It acts on the GABA system, but possibly in a different way from benzodiazepines, nonbenzodiazepines and barbiturates - (Valium, Sodium Pentothal, Ambien etc.). Lundbeck states that gaboxadol also increases deep sleep (stage 4). It is, however, not reinforcing like benzodiazepines are. [Wikipedia]

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Structure:

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Prescription Products: Not Available

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Generic Prescription Products: Not Available

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Over the Counter Products: Not Available

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International Brands

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Brand Names

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Brand Mixtures

Brand Name	Ingredients

Brand Name	Ingredients

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Categories

• No Category

Indication: Investigated for use/treatment in sleep disorders and insomnia.

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Pharmacodynamics: Not Available

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Mechanism of action: Not Available

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Absorption: Not Available

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Volume of distribution: Not Available

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Protein binding: Not Available

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Metabolism: Not Available

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Route of elimination: Not Available

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Half life: Not Available

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Clearance: Not Available

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Toxicity: Not Available

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Affected organisms

• Not Available

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SNP Mediated Adverse Drug Reactions

• Not Available

Manufacturers:

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Packagers:

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Dosage forms

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Form	Route	Strength

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Prices

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Patents

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Drug Interactions

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Food Interactions:

• Not Available

Kingdom: Organic compounds

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Super Class: Not Available

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Class: Not Available

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Sub Class: Not Available

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Direct Parent: Not Available

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Alternative Parents:

• Azacyclic compounds
• Dialkylamines
• Heteroaromatic compounds
• Hydrocarbon derivatives
• Isoxazoles
• Lactams
• Organooxygen compounds
• Oxacyclic compounds
• Oxazoles

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substituent:

• Aralkylamine
• Aromatic heteropolycyclic compound
• Azacycle
• Azole
• Heteroaromatic compound
• Hydrocarbon derivative
• Isoxazole
• Lactam
• Organoheterocyclic compound
• Organooxygen compound
• Oxacycle
• Oxazole
• Secondary aliphatic amine
• Secondary amine

Synthesis Reference: Not Available

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General Reference: Not Available

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External Links:

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ATC Codes:

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AHFS Codes:

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MSDS: Download