Detail

D-Sorbitol

Description

Name: D-Sorbitol
Type: small molecule
Groups: approved
Indication: Used as a non-stimulant laxative via an oral suspension or enema.
Accession Number: DB01638 ( EXPT02939)
Description: A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures.
Structure:
Prescription Products: Not Available
Generic Prescription Products: Not Available
Over the Counter Products: Not Available
International Brands
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Brand Mixtures
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Categories
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Pharmacology

Indication: Used as a non-stimulant laxative via an oral suspension or enema.
Pharmacodynamics: Not Available
Mechanism of action: Sorbitol exerts its laxative effect by drawing water into the large intestine, thereby stimulating bowel movements.
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Sorbitol will either be excreted in the urine by the kidneys, or metabolized to carbon dioxide and dextrose.
Half life: Not Available
Clearance: Not Available
Toxicity: Acute oral toxicity (LD50): 15900 mg/kg [Rat].
Affected organisms
  • Not Available

SNP Mediated Adverse Drug Reactions
  • Not Available

Pharmacoeconomics

Manufacturers:
  • Not Available

Packagers:
  • Not Available

Dosage forms
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Patents
CountryPatent NumberApprovedExpires (estimated)

Interactions

Drug Interactions
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Food Interactions:
  • Not Available

Taxonomy

Kingdom: Organic compounds
Super Class: Not Available
Class: Not Available
Sub Class: Not Available
Direct Parent: Not Available
Alternative Parents:
  • 1,2-diols
  • Hydrocarbon derivatives
  • Primary alcohols
  • Secondary alcohols

substituent:
  • 1,2-diol
  • Alcohol
  • Aliphatic acyclic compound
  • Hydrocarbon derivative
  • Polyol
  • Primary alcohol
  • Secondary alcohol
  • Sugar alcohol

References

Synthesis Reference: Gerhard Darsow, "Process for the preparation of epimer-free sugar alcohols from the group consisting of xylitol, sorbitol (D-glucitol), 4-O-.beta.-D-galactopyranosyl-D-glucitol and 4-O-.alpha.-D-glucopyranosyl-D-sorbitol." U.S. Patent US5162517, issued August, 1985.
General Reference: Not Available
External Links:
ResourceLink

ATC Codes:
  • Not Available

AHFS Codes:
  • Not Available

MSDS: Download
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