Detail

Verapamil

Description

Name: Verapamil
Type: small molecule
Groups: approved
Indication: For the treatment of hypertension, angina, and cluster headache prophylaxis.
Accession Number: DB00661 ( APRD00335)
Description: A calcium channel blocker that is a class IV anti-arrhythmia agent. [PubChem]
Structure:
Prescription Products:
NameDosageStrengthRouteMarketing StartMarketing EndCountry
Alti-verapamil - 120mgtablet120 mgoral31-12-199003-08-2004Canada
Alti-verapamil - 80mgtablet80 mgoral31-12-199003-08-2004Canada
Calantablet, film coated80 mg/1oral10-09-1984US
Calantablet, film coated120 mg/1oral10-09-1984US
Calan SRtablet, film coated, extended release240 mg/1oral16-12-1986US
Calan SRtablet, film coated, extended release120 mg/1oral06-03-1991US
Calan SRtablet, film coated, extended release180 mg/1oral15-12-1989US
Covera-HStablet (extended-release)180 mgoral13-11-199715-02-2013Canada
Covera-HStablet (extended-release)240 mgoral13-11-199715-02-2013Canada
Covera-HStablet, extended release180 mg/1oral26-02-1996US
Covera-HStablet, extended release240 mg/1oral26-02-1996US
Dom-verapamil SR 240mg Tabletstablet (extended-release)240 mgoral16-12-1999Canada
Isoptin Inj 2.5mg/mlliquid2.5 mgintravenous31-12-198431-07-2007Canada
Isoptin SRtablet (extended-release)240 mgoral31-12-1988Canada
Isoptin SRtablet (extended-release)120 mgoral31-12-1991Canada
Isoptin SRtablet (extended-release)180 mgoral21-04-1994Canada
Isoptin Tab 120mgtablet120 mgoral31-12-198231-07-2007Canada
Isoptin Tab 80mgtablet80 mgoral31-12-198231-07-2007Canada
Med Verapamil Tabletstablet80 mgoral08-03-199929-03-2011Canada
Med Verapamil Tabletstablet120 mgoral08-03-199929-03-2011Canada
Mylan-verapamiltablet80 mgoral25-05-1998Canada
Mylan-verapamiltablet120 mgoral11-05-1998Canada
Mylan-verapamil SRtablet (extended-release)180 mgoral31-12-1996Canada
Mylan-verapamil SRtablet (extended-release)120 mgoral31-12-1996Canada
Mylan-verapamil SRtablet (extended-release)240 mgoral31-12-1996Canada
Novo-veramiltablet80 mgoral31-12-1989Canada
Novo-veramiltablet120 mgoral31-12-1989Canada
Novo-veramil SRtablet (extended-release)240 mgoral31-12-1996Canada
Nu-verap SRtablet (extended-release)120 mgoral01-01-1970Canada
Nu-verap SRtablet (extended-release)180 mgoral01-01-1970Canada
Nu-verap SRtablet (extended-release)240 mgoral19-07-200404-09-2012Canada
Nu-verap Tab 120mgtablet120 mgoral31-12-199004-09-2012Canada
Nu-verap Tab 80mgtablet80 mgoral31-12-199004-09-2012Canada
Penta-verapamil - 120mgtablet120 mgoral25-06-199730-07-2004Canada
Penta-verapamil - 80mgtablet80 mgoral25-06-199730-07-2004Canada
PHL-verapamil SRtablet (extended-release)240 mgoral31-05-2002Canada
PMS-verapamil SRtablet (extended-release)240 mgoral01-09-1999Canada
Pro-verapamil SRtablet (extended-release)240 mgoral09-07-2008Canada
Pro-verapamil SRtablet (extended-release)120 mgoral15-06-2009Canada
Pro-verapamil SRtablet (extended-release)180 mgoral15-06-2009Canada
Riva-verapamil SRtablet (extended-release)240 mgoral14-09-2005Canada
Tarkatablet, film coated, extended releaseArrayoral27-05-2005US
Tarkatablet, film coated, extended releaseArrayoral25-06-2009US
Tarkatablet (extended-release)Arrayoral15-07-2002Canada
Tarkatablet (extended-release)Arrayoral15-07-200212-11-2010Canada
Tarkatablet, film coated, extended releaseArrayoral22-10-1996US
Tarkatablet, film coated, extended releaseArrayoral22-10-1996US
Tarkatablet, film coated, extended releaseArrayoral22-10-1996US
Tarkatablet, film coated, extended releaseArrayoral22-10-1996US
Tarkatablet, film coated, extended releaseArrayoral01-01-2009US
Tarkatablet (extended-release)Arrayoral15-07-2002Canada
Tarkatablet (extended-release)Arrayoral15-07-200212-11-2010Canada
Taro-verapamil Tab 120mgtablet120 mgoral31-12-199331-08-2000Canada
Taro-verapamil Tab 80mgtablet80 mgoral31-12-199331-08-2000Canada
Trandolapril and Verapamil Hydrochloridetablet, film coated, extended releaseArrayoral30-08-2010US
Trandolapril and Verapamil Hydrochloridetablet, film coated, extended releaseArrayoral26-05-2010US
Trandolapril and Verapamil Hydrochloridetablet, film coated, extended releaseArrayoral26-05-2010US
Trandolapril and Verapamil Hydrochloridetablet, film coated, extended releaseArrayoral05-05-2010US
Trandolapril and Verapamil Hydrochloride ERtablet, film coated, extended releaseArrayoral25-02-2015US
Trandolapril and Verapamil Hydrochloride ERtablet, film coated, extended releaseArrayoral25-02-2015US
Trandolapril and Verapamil Hydrochloride ERtablet, film coated, extended releaseArrayoral25-02-2015US
Trandolapril and Verapamil Hydrochloride ERtablet, film coated, extended releaseArrayoral25-02-2015US
Verapamil Hydrochloridecapsule, delayed release pellets180 mg/1oral29-05-1990US
Verapamil Hydrochloridecapsule, delayed release pellets120 mg/1oral24-07-2012US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral01-07-2009US
Verapamil Hydrochloridecapsule, delayed release pellets360 mg/1oral12-02-2009US
Verapamil Hydrochloridecapsule, delayed release pellets120 mg/1oral29-05-1990US
Verapamil Hydrochloridecapsule, delayed release pellets180 mg/1oral29-05-1990US
Verapamil Hydrochloridecapsule, delayed release pellets240 mg/1oral29-05-1990US
Verapamil Hydrochloridecapsule, delayed release pellets360 mg/1oral29-05-1990US
Verapamil Hydrochloridecapsule, delayed release pellets360 mg/1oral29-05-1990US
Verapamil Hydrochloridetablet, film coated, extended release120 mg/1oral01-07-2009US
Verapamil Hydrochloridecapsule, extended release100 mg/1oral25-11-1998US
Verapamil Hydrochloridecapsule, extended release200 mg/1oral25-11-1998US
Verapamil Hydrochloridecapsule, extended release300 mg/1oral25-11-1998US
Verapamil Hydrochloride Injection 2.5mg/mlsolution2.5 mgintravenous31-12-1994Canada
Verapamil Hydrochloride Injection USPliquid2.5 mgintravenous31-12-1995Canada
Verapamil Injection 2.5mg/mlliquid2.5 mgintravenous31-12-199410-08-2005Canada
Verapamil SRtablet (extended-release)240 mgoral22-06-200920-06-2014Canada
Verapamil Tab 80mgtablet80 mgoral31-12-199023-07-2012Canada
Verapamil-120 Tabtablet120 mgoral31-12-199023-07-2009Canada
Verelancapsule, delayed release pellets120 mg/1oral29-05-1990US
Verelancapsule, delayed release pellets180 mg/1oral29-05-1990US
Verelancapsule, delayed release pellets240 mg/1oral29-05-1990US
Verelancapsule, delayed release pellets360 mg/1oral29-05-1990US
Verelancapsule (sustained-release)240 mgoral31-12-1994Canada
Verelancapsule, delayed release pellets360 mg/1oral12-06-2003US
Verelancapsule (sustained-release)180 mgoral31-12-1994Canada
Verelancapsule (sustained-release)120 mgoral31-12-1994Canada
Verelancapsule, delayed release pellets240 mg/1oral12-08-2004US
Verelancapsule, delayed release pellets180 mg/1oral29-05-1990US
Verelancapsule, delayed release pellets120 mg/1oral29-05-1990US
Verelancapsule, delayed release pellets240 mg/1oral29-05-1990US
Verelancapsule, delayed release pellets360 mg/1oral29-05-1990US
Verelan PMcapsule, extended release300 mg/1oral25-11-1998US
Verelan PMcapsule, extended release300 mg/1oral25-11-1998US
Verelan PMcapsule, extended release100 mg/1oral25-11-1998US
Verelan PMcapsule, extended release200 mg/1oral25-11-1998US
Verelan PMcapsule, extended release300 mg/1oral25-11-1998US
Verelan PMcapsule, extended release100 mg/1oral25-11-1998US
Verelan PMcapsule, extended release200 mg/1oral25-11-1998US

Generic Prescription Products:
NameDosageStrengthRouteMarketing StartMarketing EndCountry
Apo-verap SRtablet (extended-release)120 mgoral24-04-2003Canada
Apo-verap SRtablet (extended-release)180 mgoral24-04-2003Canada
Apo-verap SRtablet (extended-release)240 mgoral24-04-2003Canada
Apo-verap Tab 80mgtablet80 mgoral31-12-1989Canada
Apo-verap Tablet 120mgtablet120 mgoral31-12-1989Canada
Verapamiltablet, extended release180 mg/1oral05-08-2011US
Verapamiltablet, film coated, extended release120 mg/1oral14-01-2014US
Verapamiltablet, film coated, extended release240 mg/1oral14-01-2014US
Verapamiltablet, film coated, extended release120 mg/1oral19-11-2012US
Verapamiltablet, film coated, extended release180 mg/1oral19-11-2012US
Verapamiltablet, film coated, extended release180 mg/1oral14-01-201431-12-2015US
Verapamiltablet, film coated, extended release240 mg/1oral19-11-2012US
Verapamiltablet, film coated, extended release180 mg/1oral05-02-2013US
Verapamiltablet, film coated, extended release120 mg/1oral21-04-2014US
Verapamiltablet, film coated, extended release180 mg/1oral19-11-2012US
Verapamil Hydrochlorideinjection, solution2.5 mg/mLintravenous25-03-2011US
Verapamil Hydrochloridetablet, film coated, extended release120 mg/1oral04-12-2014US
Verapamil Hydrochloridetablet, film coated, extended release180 mg/1oral04-12-2014US
Verapamil Hydrochloridetablet, extended release120 mg/1oral01-01-2012US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral04-12-2014US
Verapamil Hydrochloridetablet, extended release180 mg/1oral01-01-2012US
Verapamil Hydrochloridetablet, extended release240 mg/1oral01-01-2012US
Verapamil Hydrochlorideinjection, solution2.5 mg/mLintravenous25-03-2011US
Verapamil Hydrochloridecapsule, extended release120 mg/1oral22-11-2010US
Verapamil Hydrochloridetablet, extended release240 mg/1oral26-09-2013US
Verapamil Hydrochlorideinjection, solution2.5 mg/mLintravenous06-05-1987US
Verapamil Hydrochloridetablet, extended release180 mg/1oral24-08-2011US
Verapamil Hydrochloridecapsule, extended release300 mg/1oral20-12-2007US
Verapamil Hydrochloridetablet80 mg/1oral24-04-1995US
Verapamil Hydrochloridetablet120 mg/1oral05-02-1996US
Verapamil Hydrochloridetablet, extended release180 mg/1oral25-07-2011US
Verapamil Hydrochloridetablet, film coated80 mg/1oral15-08-2012US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral15-02-2011US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral17-09-2009US
Verapamil Hydrochloridetablet, film coated120 mg/1oral01-10-1986US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral17-09-2009US
Verapamil Hydrochloridetablet80 mg/1oral08-08-2011US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral20-04-2010US
Verapamil Hydrochloridetablet, film coated, extended release120 mg/1oral05-08-2011US
Verapamil Hydrochloridetablet, film coated, extended release180 mg/1oral05-08-2011US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral20-08-2010US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral17-09-2009US
Verapamil Hydrochloridetablet, film coated120 mg/1oral15-08-2012US
Verapamil Hydrochloridetablet, film coated, extended release120 mg/1oral28-11-2000US
Verapamil Hydrochloridetablet, film coated, extended release120 mg/1oral01-01-2014US
Verapamil Hydrochloridetablet80 mg/1oral16-11-2011US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral04-06-2012US
Verapamil Hydrochloridetablet, film coated80 mg/1oral01-10-1986US
Verapamil Hydrochloridetablet, film coated, extended release180 mg/1oral20-04-2010US
Verapamil Hydrochloridetablet, film coated120 mg/1oral01-10-1986US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral17-09-2009US
Verapamil Hydrochloridetablet, film coated40 mg/1oral29-06-1993US
Verapamil Hydrochloridetablet, film coated120 mg/1oral17-12-2013US
Verapamil Hydrochloridetablet, film coated80 mg/1oral01-10-1986US
Verapamil Hydrochloridetablet, film coated120 mg/1oral01-10-1986US
Verapamil Hydrochloridetablet, film coated, extended release120 mg/1oral01-07-2009US
Verapamil Hydrochloridetablet, film coated40 mg/1oral29-06-1993US
Verapamil Hydrochlorideinjection, solution2.5 mg/mLintravenous25-03-2011US
Verapamil Hydrochloridetablet80 mg/1oral07-01-2011US
Verapamil Hydrochloridetablet120 mg/1oral07-01-2011US
Verapamil Hydrochloridetablet, film coated, extended release180 mg/1oral15-01-1996US
Verapamil Hydrochloridetablet, extended release240 mg/301oral27-05-2014US
Verapamil Hydrochloridetablet120 mg/1oral07-01-2011US
Verapamil Hydrochlorideinjection, solution2.5 mg/mLintravenous01-09-2010US
Verapamil Hydrochloridetablet, extended release180 mg/1oral01-01-2012US
Verapamil Hydrochloridetablet, extended release240 mg/1oral01-01-2012US
Verapamil Hydrochloridecapsule, extended release120 mg/1oral19-05-1999US
Verapamil Hydrochloridetablet40 mg/1oral07-01-2011US
Verapamil Hydrochloridecapsule, extended release180 mg/1oral19-05-1999US
Verapamil Hydrochloridecapsule, extended release240 mg/1oral19-05-1999US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral15-04-1996US
Verapamil Hydrochloridetablet, film coated80 mg/1oral01-10-1986US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral01-08-1992US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral12-07-2012US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral25-03-1996US
Verapamil Hydrochloridetablet, film coated, extended release120 mg/1oral17-04-1998US
Verapamil Hydrochloridetablet, extended release180 mg/1oral01-11-2014US
Verapamil Hydrochloridetablet, film coated40 mg/1oral29-06-1993US
Verapamil Hydrochloridetablet, film coated, extended release180 mg/1oral15-11-1998US
Verapamil Hydrochloridetablet, film coated, extended release120 mg/1oral10-03-2014US
Verapamil Hydrochloridetablet, film coated, extended release180 mg/1oral29-01-2014US
Verapamil Hydrochloridetablet, film coated, extended release180 mg/1oral23-02-2012US
Verapamil Hydrochloridecapsule, extended release120 mg/1oral01-10-1999US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral07-04-2014US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral23-02-2012US
Verapamil Hydrochloridetablet, film coated, extended release180 mg/1oral22-09-1997US
Verapamil Hydrochloridetablet, film coated120 mg/1oral01-10-1986US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral25-03-1996US
Verapamil Hydrochloridetablet120 mg/1oral27-06-2014US
Verapamil Hydrochloridetablet, film coated80 mg/1oral01-10-1986US
Verapamil Hydrochloridetablet, film coated120 mg/1oral01-10-1986US
Verapamil Hydrochloridetablet, extended release240 mg/1oral07-12-2011US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral14-05-2013US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral22-05-2013US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral17-09-2009US
Verapamil Hydrochlorideinjection, solution2.5 mg/mLintravenous20-10-1998US
Verapamil Hydrochloridetablet, film coated80 mg/1oral01-10-1986US
Verapamil Hydrochloridetablet120 mg/1oral13-12-2011US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral17-09-2009US
Verapamil Hydrochloridetablet, film coated, extended release120 mg/1oral05-08-2011US
Verapamil Hydrochlorideinjection, solution2.5 mg/mLintravenous06-05-1987US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral09-05-2000US
Verapamil Hydrochloridecapsule, extended release100 mg/1oral07-08-2008US
Verapamil Hydrochlorideinjection, solution2.5 mg/mLintravenous01-03-2010US
Verapamil Hydrochloridetablet, film coated, extended release180 mg/1oral14-03-2013US
Verapamil Hydrochloridecapsule, extended release200 mg/1oral17-05-2010US
Verapamil Hydrochloridetablet, film coated, extended release120 mg/1oral25-02-1997US
Verapamil Hydrochloridetablet, film coated, extended release180 mg/1oral05-08-2011US
Verapamil Hydrochloridetablet, film coated, extended release120 mg/1oral15-05-2013US
Verapamil Hydrochloridetablet, film coated, extended release180 mg/1oral22-09-1997US
Verapamil Hydrochloridetablet, film coated, extended release180 mg/1oral01-07-2009US
Verapamil Hydrochloridetablet, film coated120 mg/1oral01-10-1986US
Verapamil Hydrochloridetablet, film coated80 mg/1oral24-04-1995US
Verapamil Hydrochloridetablet, film coated120 mg/1oral05-02-1996US
Verapamil Hydrochloridetablet, film coated, extended release120 mg/1oral10-10-1997US
Verapamil Hydrochloridetablet, film coated, extended release240 mg/1oral01-07-2009US
Verapamil Hydrochloridetablet240 mg/1oral02-10-2012US
Verapamil Hydrochloridetablet, film coated120 mg/1oral04-05-2011US
Verapamil Hydrochloride PMcapsule, extended release100 mg/1oral09-08-2007US
Verapamil Hydrochloride PMcapsule, extended release200 mg/1oral09-08-2007US
Verapamil Hydrochloride PMcapsule, extended release300 mg/1oral09-08-2007US

Over the Counter Products: Not Available
International Brands
  • No Brands

Brand Names
  • No Brands

Brand Mixtures
Brand NameIngredients
CalanVerapamil
CalanVerapamil
Calan SRVerapamil
Calan SRVerapamil
Calan SRVerapamil
Covera-HSVerapamil
Covera-HSVerapamil
TarkaTrandolapril + Verapamil
TarkaTrandolapril + Verapamil
TarkaTrandolapril + Verapamil
TarkaTrandolapril + Verapamil
VerelanVerapamil
VerelanVerapamil
VerelanVerapamil
VerelanVerapamil
Verelan PMVerapamil
Verelan PMVerapamil
Verelan PMVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil Hydrochloride PMVerapamil
Verapamil Hydrochloride PMVerapamil
Verapamil Hydrochloride PMVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
VerapamilVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
VerelanVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
VerelanVerapamil
TarkaTrandolapril + Verapamil
TarkaTrandolapril + Verapamil
TarkaTrandolapril + Verapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
VerapamilVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Trandolapril and Verapamil Hydrochloride ERTrandolapril + Verapamil
Trandolapril and Verapamil Hydrochloride ERTrandolapril + Verapamil
Trandolapril and Verapamil Hydrochloride ERTrandolapril + Verapamil
Trandolapril and Verapamil Hydrochloride ERTrandolapril + Verapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
VerapamilVerapamil
VerapamilVerapamil
VerapamilVerapamil
Verapamil HydrochlorideVerapamil
VerapamilVerapamil
VerapamilVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verelan PMVerapamil
Verelan PMVerapamil
Verelan PMVerapamil
VerelanVerapamil
VerelanVerapamil
VerelanVerapamil
VerelanVerapamil
Verelan PMVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
VerapamilVerapamil
VerapamilVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Trandolapril and Verapamil HydrochlorideTrandolapril + Verapamil
Trandolapril and Verapamil HydrochlorideTrandolapril + Verapamil
Trandolapril and Verapamil HydrochlorideTrandolapril + Verapamil
Trandolapril and Verapamil HydrochlorideTrandolapril + Verapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
VerapamilVerapamil
Verapamil HydrochlorideVerapamil
Apo-verap Tab 80mgVerapamil
VerelanVerapamil
VerelanVerapamil
VerelanVerapamil
Verapamil Hydrochloride Injection 2.5mg/mlVerapamil
Verapamil Hydrochloride Injection USPVerapamil
Mylan-verapamil SRVerapamil
Mylan-verapamil SRVerapamil
Mylan-verapamil SRVerapamil
Novo-veramil SRVerapamil
PMS-verapamil SRVerapamil
Mylan-verapamilVerapamil
Mylan-verapamilVerapamil
TarkaVerapamil + Trandolapril
PHL-verapamil SRVerapamil
Dom-verapamil SR 240mg TabletsVerapamil
Apo-verap SRVerapamil
Apo-verap SRVerapamil
Apo-verap SRVerapamil
Riva-verapamil SRVerapamil
Pro-verapamil SRVerapamil
Pro-verapamil SRVerapamil
Pro-verapamil SRVerapamil
Novo-veramilVerapamil
Novo-veramilVerapamil
Apo-verap Tablet 120mgVerapamil
Verapamil Tab 80mgVerapamil
Verapamil-120 TabVerapamil
Alti-verapamil - 80mgVerapamil
Alti-verapamil - 120mgVerapamil
Nu-verap Tab 120mgVerapamil
Nu-verap Tab 80mgVerapamil
Taro-verapamil Tab 80mgVerapamil
Verapamil Injection 2.5mg/mlVerapamil
Taro-verapamil Tab 120mgVerapamil
Penta-verapamil - 80mgVerapamil
Penta-verapamil - 120mgVerapamil
Isoptin Tab 80mgVerapamil
Isoptin Tab 120mgVerapamil
Covera-HSVerapamil
Covera-HSVerapamil
TarkaVerapamil + Trandolapril
Med Verapamil TabletsVerapamil
Med Verapamil TabletsVerapamil
TarkaVerapamil + Trandolapril
Isoptin Inj 2.5mg/mlVerapamil
Nu-verap SRVerapamil
Verapamil SRVerapamil
Nu-verap SRVerapamil
Nu-verap SRVerapamil
Isoptin SRVerapamil
Isoptin SRVerapamil
TarkaVerapamil + Trandolapril
Isoptin SRVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil
Verapamil HydrochlorideVerapamil

Categories
  • Anti-Arrhythmia Agents
  • Vasodilator Agents
  • Calcium Channel Blockers
  • P-glycoprotein/ABCB1 Inhibitors
  • P-glycoprotein/ABCB1 Substrates

Pharmacology

Indication: For the treatment of hypertension, angina, and cluster headache prophylaxis.
Pharmacodynamics: Not Available
Mechanism of action: Verapamil inhibits voltage-dependent calcium channels. Specifically, its effect on L-type calcium channels in the heart causes a reduction in ionotropy and chronotropy, thuis reducing heart rate and blood pressure. Verapamil's mechanism of effect in cluster headache is thought to be linked to its calcium-channel blocker effect, but which channel subtypes are involved is presently not known.
Absorption: 90%
Volume of distribution: Not Available
Protein binding: 90%
Metabolism: Not Available
Route of elimination: Approximately 70% of an administered dose is excreted as metabolites in the urine and 16% or more in the feces within 5 days. About 3% to 4% is excreted in the urine as unchanged drug.
Half life: 2.8-7.4 hours
Clearance: Not Available
Toxicity: LD50=8 mg/kg (i.v. in mice)
Affected organisms
  • Not Available

SNP Mediated Adverse Drug Reactions
  • Not Available

Pharmacoeconomics

Manufacturers:
  • Mylan pharmaceuticals inc
  • Elan drug delivery inc
  • Gd searle llc
  • Fsc laboratories inc
  • Abraxis pharmaceutical products
  • Bedford laboratories div ben venue laboratories inc
  • Hospira inc
  • International medication system
  • Luitpold pharmaceuticals inc
  • Marsam pharmaceuticals llc
  • Smith and nephew solopak div smith and nephew
  • Solopak medical products inc
  • Ranbaxy laboratories inc
  • Glenmark generics ltd
  • Ivax pharmaceuticals inc sub teva pharmaceuticals usa
  • Par pharmaceutical inc
  • Pliva inc
  • Actavis elizabeth llc
  • Heritage pharmaceuticals inc
  • Mutual pharmaceutical co inc
  • Sandoz inc
  • Warner chilcott div warner lambert co
  • Watson laboratories inc

Packagers:
Dosage forms
FormRouteStrength
Tabletoral80 mg
Tablet, film coatedoral120 mg/1
Tablet, film coatedoral80 mg/1
Tablet, film coated, extended releaseoral120 mg/1
Tablet, film coated, extended releaseoral180 mg/1
Tablet, film coated, extended releaseoral240 mg/1
Tablet, extended releaseoral180 mg/1
Tablet, extended releaseoral240 mg/1
Tabletoral120 mg
Tablet (extended-release)oral120 mg
Tablet (extended-release)oral180 mg
Tablet (extended-release)oral240 mg
Tablet (extended-release)oral
Tablet, film coated, extended releaseoral
Capsule, extended releaseoral120 mg/1
Capsule, extended releaseoral180 mg/1
Capsule, extended releaseoral240 mg/1
Injection, solutionintravenous2.5 mg/mL
Tabletoral120 mg/1
Tabletoral240 mg/1
Tabletoral40 mg/1
Tabletoral80 mg/1
Tablet, extended releaseoral120 mg/1
Tablet, extended releaseoral240 mg/301
Tablet, film coatedoral40 mg/1
Solutionintravenous2.5 mg
Liquidintravenous2.5 mg
Capsule (sustained-release)oral120 mg
Capsule (sustained-release)oral180 mg
Capsule (sustained-release)oral240 mg
Capsule, delayed release pelletsoral120 mg/1
Capsule, delayed release pelletsoral180 mg/1
Capsule, delayed release pelletsoral240 mg/1
Capsule, delayed release pelletsoral360 mg/1
Capsule, extended releaseoral100 mg/1
Capsule, extended releaseoral200 mg/1
Capsule, extended releaseoral300 mg/1

Prices
Unit descriptionCostUnit
Verapamil HCl CR 120 mg Controlled Release Tabs$1.12tab
Verapamil 2.5 mg/ml vial$1.18ml
Calan 80 mg tablet$1.25tablet
Isoptin Sr 120 mg Sustained-Release Tablet$1.34tablet
Verapamil HCl CR 180 mg Controlled Release Tabs$1.41tab
Verapamil HCl CR 120 mg 24 Hour Capsule$1.43capsule
Calan sr 180 mg caplet sa$1.46caplet
Verapamil HCl CR 180 mg 24 Hour Capsule$1.5capsule
Isoptin Sr 180 mg Sustained-Release Tablet$1.52tablet
Calan 120 mg tablet$1.56tablet
Verapamil HCl CR 240 mg Controlled Release Tabs$1.6tab
Verapamil HCl CR 240 mg 24 Hour Capsule$1.69capsule
Calan sr 240 mg caplet sa$1.77caplet
Isoptin Sr 240 mg Sustained-Release Tablet$2.03tablet
Verapamil HCl CR 100 mg 24 Hour Capsule$2.04capsule
Verapamil HCl CR 360 mg 24 Hour Capsule$2.1capsule
Covera-hs 180 mg tablet sa$2.11tablet
Calan sr 120 mg caplet$2.13caplet
Isoptin SR 120 mg Controlled Release Tabs$2.16tab
Covera-HS 180 mg 24 Hour tablet$2.2tablet
Calan SR 120 mg Controlled Release Tabs$2.27tab
Isoptin sr 120 mg tablet$2.29tablet
Verapamil HCl CR 200 mg 24 Hour Capsule$2.62capsule
Calan sr 180 mg caplet$2.7caplet
Isoptin SR 180 mg Controlled Release Tabs$2.74tab
Calan SR 180 mg Controlled Release Tabs$2.8tab
Isoptin sr 180 mg tablet$2.9tablet
Covera-hs 240 mg tablet sa$2.97tablet
Calan sr 240 mg caplet$3.09caplet
Covera-HS 240 mg 24 Hour tablet$3.09tablet
Verelan pm 100 mg cap pellet$3.13pellet
Isoptin SR 240 mg Controlled Release Tabs$3.14tab
Calan SR 240 mg Controlled Release Tabs$3.15tab
Verapamil hcl powder$3.24g
Isoptin sr 240 mg tablet$3.32tablet
Verapamil HCl CR 300 mg 24 Hour Capsule$3.82capsule
Verelan 120 mg cap pellet$3.87pellet
Verelan pm 200 mg cap pellet$4.04pellet
Verelan 180 mg cap pellet$4.06pellet
Verelan 180 mg 24 Hour Capsule$4.22capsule
Verelan 240 mg cap pellet$4.58pellet
Verelan 240 mg 24 Hour Capsule$4.76capsule
Verelan pm 300 mg cap pellet$5.87pellet
Verelan 360 mg cap pellet$6.73pellet
Verelan 360 mg 24 Hour Capsule$6.82capsule
Verapamil 40 mg tablet$0.28tablet
Verapamil HCl 40 mg tablet$0.29tablet
Apo-Verap 80 mg Tablet$0.29tablet
Mylan-Verapamil 80 mg Tablet$0.29tablet
Nu-Verap 80 mg Tablet$0.29tablet
Verapamil 80 mg tablet$0.31tablet
Verapamil 120 mg tablet$0.39tablet
Apo-Verap 120 mg Tablet$0.45tablet
Mylan-Verapamil 120 mg Tablet$0.45tablet
Nu-Verap 120 mg Tablet$0.45tablet
Verapamil HCl 80 mg tablet$0.56tablet
Apo-Verap Sr 180 mg Sustained-Release Tablet$0.69tablet
Mylan-Verapamil Sr 180 mg Sustained-Release Tablet$0.69tablet
Verapamil HCl 120 mg tablet$0.71tablet
Apo-Verap Sr 120 mg Sustained-Release Tablet$0.72tablet
Mylan-Verapamil Sr 120 mg Sustained-Release Tablet$0.72tablet
Calan 40 mg tablet$0.76tablet
Apo-Verap Sr 240 mg Sustained-Release Tablet$0.91tablet
Mylan-Verapamil Sr 240 mg Sustained-Release Tablet$0.91tablet
Novo-Veramil Sr 240 mg Sustained-Release Tablet$0.91tablet
Pms-Verapamil Sr 240 mg Sustained-Release Tablet$0.91tablet

Patents
CountryPatent NumberApprovedExpires (estimated)
5785994United States1992-10-222009-10-22
6096339United States1997-04-042017-04-04

Interactions

Drug Interactions
DrugInteraction
AbirateroneThe serum concentration of Verapamil can be increased when it is combined with Abiraterone.
AcetaminophenThe metabolism of Verapamil can be increased when combined with Acetaminophen.
Acetylsalicylic acidVerapamil may increase the anticoagulant activities of Acetylsalicylic acid.
AfatinibThe serum concentration of Afatinib can be increased when it is combined with Verapamil.
AldesleukinThe risk or severity of adverse effects can be increased when Aldesleukin is combined with Verapamil.
AlfuzosinAlfuzosin may increase the hypotensive activities of Verapamil.
AliskirenThe serum concentration of Aliskiren can be increased when it is combined with Verapamil.
AmifostineVerapamil may increase the hypotensive activities of Amifostine.
AmiodaroneThe serum concentration of Amiodarone can be increased when it is combined with Verapamil.
AmlodipineAmlodipine may increase the hypotensive activities of Verapamil.
AmobarbitalThe metabolism of Verapamil can be increased when combined with Amobarbital.
ApixabanThe serum concentration of Apixaban can be increased when it is combined with Verapamil.
AprepitantThe serum concentration of Verapamil can be increased when it is combined with Aprepitant.
AripiprazoleThe serum concentration of Aripiprazole can be increased when it is combined with Verapamil.
AtorvastatinThe serum concentration of Verapamil can be increased when it is combined with Atorvastatin.
AtosibanThe risk or severity of adverse effects can be increased when Verapamil is combined with Atosiban.
Atracurium besylateVerapamil may increase the neuromuscular blocking activities of Atracurium besylate.
AvanafilThe serum concentration of Avanafil can be increased when it is combined with Verapamil.
AzithromycinThe serum concentration of Verapamil can be increased when it is combined with Azithromycin.
BatimastatThe metabolism of Verapamil can be decreased when combined with Batimastat.
BendroflumethiazideThe serum concentration of Bendroflumethiazide can be increased when it is combined with Verapamil.
BexaroteneThe serum concentration of Verapamil can be decreased when it is combined with Bexarotene.
BosentanThe serum concentration of Verapamil can be decreased when it is combined with Bosentan.
BosutinibThe serum concentration of Bosutinib can be increased when it is combined with Verapamil.
Brentuximab vedotinThe serum concentration of Brentuximab vedotin can be increased when it is combined with Verapamil.
BretyliumBretylium may increase the bradycardic activities of Verapamil.
BrexpiprazoleThe serum concentration of Brexpiprazole can be increased when it is combined with Verapamil.
BrimonidineBrimonidine may increase the antihypertensive activities of Verapamil.
BudesonideThe serum concentration of Budesonide can be increased when it is combined with Verapamil.
BuspironeThe metabolism of Buspirone can be decreased when combined with Verapamil.
ButabarbitalThe metabolism of Verapamil can be increased when combined with Butabarbital.
ButalbitalThe metabolism of Verapamil can be increased when combined with Butalbital.
ButethalThe metabolism of Verapamil can be increased when combined with Butethal.
CaffeineThe metabolism of Verapamil can be increased when combined with Caffeine.
Calcium AcetateThe therapeutic efficacy of Verapamil can be decreased when used in combination with Calcium Acetate.
Calcium carbonateThe therapeutic efficacy of Verapamil can be decreased when used in combination with Calcium carbonate.
Calcium ChlorideThe therapeutic efficacy of Verapamil can be decreased when used in combination with Calcium Chloride.
Calcium citrateThe therapeutic efficacy of Verapamil can be decreased when used in combination with Calcium citrate.
Calcium gluconateThe therapeutic efficacy of Verapamil can be decreased when used in combination with Calcium gluconate.
CarbamazepineThe serum concentration of Carbamazepine can be increased when it is combined with Verapamil.
CarfilzomibThe serum concentration of Carfilzomib can be increased when it is combined with Verapamil.
CarvedilolThe serum concentration of Carvedilol can be increased when it is combined with Verapamil.
CeritinibVerapamil may increase the bradycardic activities of Ceritinib.
CetirizineThe serum concentration of Cetirizine can be increased when it is combined with Verapamil.
CilostazolThe serum concentration of Cilostazol can be increased when it is combined with Verapamil.
CimetidineThe serum concentration of Verapamil can be increased when it is combined with Cimetidine.
CiprofloxacinThe serum concentration of Ciprofloxacin can be increased when it is combined with Verapamil.
Cisatracurium besylateVerapamil may increase the neuromuscular blocking activities of Cisatracurium besylate.
ClarithromycinThe serum concentration of Verapamil can be increased when it is combined with Clarithromycin.
ClonidineClonidine may increase the atrioventricular blocking (AV block) activities of Verapamil.
ClopidogrelThe therapeutic efficacy of Clopidogrel can be decreased when used in combination with Verapamil.
CobicistatThe serum concentration of Verapamil can be increased when it is combined with Cobicistat.
ColchicineThe serum concentration of Colchicine can be increased when it is combined with Verapamil.
ConivaptanThe serum concentration of Verapamil can be increased when it is combined with Conivaptan.
CrizotinibThe serum concentration of Crizotinib can be increased when it is combined with Verapamil.
CyclosporineThe serum concentration of Cyclosporine can be increased when it is combined with Verapamil.
Dabigatran etexilateThe serum concentration of the active metabolites of Dabigatran etexilate can be increased when Dabigatran etexilate is used in combination with Verapamil.
DabrafenibThe serum concentration of Verapamil can be decreased when it is combined with Dabrafenib.
DaclatasvirThe serum concentration of Verapamil can be increased when it is combined with Daclatasvir.
DantroleneDantrolene may increase the hyperkalemic activities of Verapamil.
DapoxetineThe serum concentration of Dapoxetine can be increased when it is combined with Verapamil.
DarunavirThe serum concentration of Verapamil can be increased when it is combined with Darunavir.
DasatinibThe serum concentration of Verapamil can be increased when it is combined with Dasatinib.
DaunorubicinThe serum concentration of Daunorubicin can be increased when it is combined with Verapamil.
DeferasiroxThe serum concentration of Verapamil can be decreased when it is combined with Deferasirox.
DesloratadineThe serum concentration of Desloratadine can be increased when it is combined with Verapamil.
DexamethasoneThe serum concentration of Dexamethasone can be increased when it is combined with Verapamil.
DiazoxideDiazoxide may increase the hypotensive activities of Verapamil.
DigoxinVerapamil may increase the atrioventricular blocking (AV block) activities of Digoxin.
DiltiazemThe serum concentration of Diltiazem can be increased when it is combined with Verapamil.
DipyridamoleThe serum concentration of Verapamil can be increased when it is combined with Dipyridamole.
DisopyramideThe risk or severity of adverse effects can be increased when Verapamil is combined with Disopyramide.
DocetaxelThe serum concentration of Docetaxel can be increased when it is combined with Verapamil.
DofetilideThe serum concentration of Dofetilide can be increased when it is combined with Verapamil.
DomperidoneThe serum concentration of Domperidone can be increased when it is combined with Verapamil.
DoxazosinDoxazosin may increase the hypotensive activities of Verapamil.
DoxorubicinThe serum concentration of Doxorubicin can be increased when it is combined with Verapamil.
DronabinolThe serum concentration of Dronabinol can be increased when it is combined with Verapamil.
DronedaroneVerapamil may increase the atrioventricular blocking (AV block) activities of Dronedarone.
DrospirenoneThe serum concentration of Drospirenone can be increased when it is combined with Verapamil.
DuloxetineVerapamil may increase the orthostatic hypotensive activities of Duloxetine.
EdoxabanThe serum concentration of Edoxaban can be increased when it is combined with Verapamil.
EfavirenzThe serum concentration of Verapamil can be decreased when it is combined with Efavirenz.
EletriptanThe serum concentration of Eletriptan can be increased when it is combined with Verapamil.
EliglustatThe serum concentration of Eliglustat can be increased when it is combined with Verapamil.
EplerenoneThe serum concentration of Eplerenone can be increased when it is combined with Verapamil.
ErythromycinThe serum concentration of Verapamil can be increased when it is combined with Erythromycin.
EsmololEsmolol may increase the bradycardic activities of Verapamil.
EstradiolThe serum concentration of Estradiol can be increased when it is combined with Verapamil.
EthanolThe serum concentration of Ethanol can be increased when it is combined with Verapamil.
EtoposideThe serum concentration of Etoposide can be increased when it is combined with Verapamil.
EverolimusThe serum concentration of Everolimus can be increased when it is combined with Verapamil.
FentanylThe serum concentration of Fentanyl can be increased when it is combined with Verapamil.
FexofenadineThe bioavailability of Fexofenadine can be increased when combined with Verapamil.
FingolimodVerapamil may increase the bradycardic activities of Fingolimod.
FlecainideThe risk or severity of adverse effects can be increased when Verapamil is combined with Flecainide.
FlibanserinThe serum concentration of Flibanserin can be increased when it is combined with Verapamil.
FluconazoleThe serum concentration of Verapamil can be increased when it is combined with Fluconazole.
FlunisolideThe metabolism of Flunisolide can be decreased when combined with Verapamil.
FosamprenavirThe serum concentration of Fosamprenavir can be increased when it is combined with Verapamil.
FosaprepitantThe serum concentration of Verapamil can be increased when it is combined with Fosaprepitant.
FosphenytoinThe serum concentration of Fosphenytoin can be increased when it is combined with Verapamil.
Fusidic AcidThe serum concentration of Verapamil can be increased when it is combined with Fusidic Acid.
HalofantrineThe serum concentration of Halofantrine can be increased when it is combined with Verapamil.
HeptabarbitalThe metabolism of Verapamil can be increased when combined with Heptabarbital.
HexobarbitalThe metabolism of Verapamil can be increased when combined with Hexobarbital.
HydrocodoneThe serum concentration of Hydrocodone can be increased when it is combined with Verapamil.
HydrocortisoneThe serum concentration of Hydrocortisone can be increased when it is combined with Verapamil.
IbrutinibThe serum concentration of Ibrutinib can be increased when it is combined with Verapamil.
IdarubicinThe serum concentration of Idarubicin can be increased when it is combined with Verapamil.
IdelalisibThe serum concentration of Verapamil can be increased when it is combined with Idelalisib.
IfosfamideThe serum concentration of the active metabolites of Ifosfamide can be reduced when Ifosfamide is used in combination with Verapamil resulting in a loss in efficacy.
ImatinibThe serum concentration of Imatinib can be increased when it is combined with Verapamil.
IndinavirThe serum concentration of Indinavir can be increased when it is combined with Verapamil.
IrinotecanThe serum concentration of Irinotecan can be increased when it is combined with Verapamil.
IsoflurophateThe metabolism of Verapamil can be decreased when combined with Isoflurophate.
ItraconazoleThe serum concentration of Verapamil can be increased when it is combined with Itraconazole.
IvabradineThe serum concentration of Ivabradine can be increased when it is combined with Verapamil.
IvacaftorThe serum concentration of Ivacaftor can be increased when it is combined with Verapamil.
IvermectinThe serum concentration of Ivermectin can be increased when it is combined with Verapamil.
KetoconazoleThe serum concentration of Verapamil can be increased when it is combined with Ketoconazole.
LacosamideVerapamil may increase the atrioventricular blocking (AV block) activities of Lacosamide.
LapatinibThe serum concentration of Lapatinib can be increased when it is combined with Verapamil.
LedipasvirThe serum concentration of Ledipasvir can be increased when it is combined with Verapamil.
LevodopaVerapamil may increase the orthostatic hypotensive activities of Levodopa.
LithiumVerapamil may increase the neurotoxic activities of Lithium.
LomitapideThe serum concentration of Lomitapide can be increased when it is combined with Verapamil.
LoperamideThe serum concentration of Loperamide can be increased when it is combined with Verapamil.
LopinavirThe serum concentration of Lopinavir can be increased when it is combined with Verapamil.
LoratadineThe serum concentration of Loratadine can be increased when it is combined with Verapamil.
LovastatinThe serum concentration of Lovastatin can be increased when it is combined with Verapamil.
LuliconazoleThe serum concentration of Verapamil can be increased when it is combined with Luliconazole.
LurasidoneThe serum concentration of Lurasidone can be increased when it is combined with Verapamil.
Magnesium chlorideThe risk or severity of adverse effects can be increased when Verapamil is combined with Magnesium chloride.
Magnesium citrateThe risk or severity of adverse effects can be increased when Verapamil is combined with Magnesium citrate.
Magnesium hydroxideThe risk or severity of adverse effects can be increased when Verapamil is combined with Magnesium hydroxide.
Magnesium oxideThe risk or severity of adverse effects can be increased when Verapamil is combined with Magnesium oxide.
Magnesium salicylateThe risk or severity of adverse effects can be increased when Verapamil is combined with Magnesium salicylate.
Magnesium SulfateThe risk or severity of adverse effects can be increased when Verapamil is combined with Magnesium Sulfate.
MefloquineThe serum concentration of Verapamil can be increased when it is combined with Mefloquine.
MetforminThe therapeutic efficacy of Metformin can be decreased when used in combination with Verapamil.
MethohexitalThe metabolism of Verapamil can be increased when combined with Methohexital.
MethotrexateThe serum concentration of Methotrexate can be increased when it is combined with Verapamil.
MethylphenidateMethylphenidate may decrease the antihypertensive activities of Verapamil.
MidodrineVerapamil may increase the bradycardic activities of Midodrine.
MifepristoneThe serum concentration of Verapamil can be increased when it is combined with Mifepristone.
MirabegronThe serum concentration of Verapamil can be increased when it is combined with Mirabegron.
MitomycinThe serum concentration of Mitomycin can be increased when it is combined with Verapamil.
MitotaneThe serum concentration of Verapamil can be decreased when it is combined with Mitotane.
MolsidomineMolsidomine may increase the hypotensive activities of Verapamil.
MorphineThe serum concentration of Morphine can be increased when it is combined with Verapamil.
MoxonidineMoxonidine may increase the hypotensive activities of Verapamil.
NadololVerapamil may increase the hypotensive activities of Nadolol.
NafcillinThe metabolism of Verapamil can be increased when combined with Nafcillin.
NaloxegolThe serum concentration of Naloxegol can be increased when it is combined with Verapamil.
NelfinavirThe serum concentration of Nelfinavir can be increased when it is combined with Verapamil.
NetupitantThe serum concentration of Verapamil can be increased when it is combined with Netupitant.
NicardipineThe serum concentration of Nicardipine can be increased when it is combined with Verapamil.
NicorandilNicorandil may increase the hypotensive activities of Verapamil.
NilotinibThe serum concentration of Verapamil can be increased when it is combined with Nilotinib.
NimodipineThe serum concentration of Nimodipine can be increased when it is combined with Verapamil.
NintedanibThe serum concentration of Nintedanib can be increased when it is combined with Verapamil.
NitroprussideVerapamil may increase the hypotensive activities of Nitroprusside.
NorgestimateThe serum concentration of Norgestimate can be increased when it is combined with Verapamil.
ObinutuzumabVerapamil may increase the hypotensive activities of Obinutuzumab.
OctreotideOctreotide may increase the bradycardic activities of Verapamil.
OlaparibThe serum concentration of Olaparib can be increased when it is combined with Verapamil.
OndansetronThe serum concentration of Ondansetron can be increased when it is combined with Verapamil.
OxycodoneThe risk or severity of adverse effects can be increased when Verapamil is combined with Oxycodone.
PaclitaxelThe serum concentration of Paclitaxel can be increased when it is combined with Verapamil.
PalbociclibThe serum concentration of Verapamil can be increased when it is combined with Palbociclib.
PaliperidoneThe serum concentration of Paliperidone can be increased when it is combined with Verapamil.
PancuroniumVerapamil may increase the neuromuscular blocking activities of Pancuronium.
PazopanibThe serum concentration of Pazopanib can be increased when it is combined with Verapamil.
PentobarbitalThe metabolism of Verapamil can be increased when combined with Pentobarbital.
PentoxifyllinePentoxifylline may increase the hypotensive activities of Verapamil.
PhenelzinePhenelzine may increase the hypotensive activities of Verapamil.
PhenobarbitalThe metabolism of Verapamil can be increased when combined with Phenobarbital.
PhenoxybenzaminePhenoxybenzamine may increase the hypotensive activities of Verapamil.
PhentolaminePhentolamine may increase the hypotensive activities of Verapamil.
PhenytoinThe serum concentration of Phenytoin can be increased when it is combined with Verapamil.
PimecrolimusThe metabolism of Pimecrolimus can be decreased when combined with Verapamil.
PimozideThe serum concentration of Pimozide can be increased when it is combined with Verapamil.
PosaconazoleThe risk or severity of adverse effects can be increased when Posaconazole is combined with Verapamil.
PrazosinPrazosin may increase the hypotensive activities of Verapamil.
PrimidoneThe metabolism of Verapamil can be increased when combined with Primidone.
ProgesteroneThe serum concentration of Verapamil can be increased when it is combined with Progesterone.
PropafenoneThe serum concentration of Propafenone can be increased when it is combined with Verapamil.
PropranololThe serum concentration of Verapamil can be increased when it is combined with Propranolol.
PrucaloprideThe serum concentration of Prucalopride can be increased when it is combined with Verapamil.
QuinidineQuinidine may increase the hypotensive activities of Verapamil.
QuinineThe serum concentration of Quinine can be increased when it is combined with Verapamil.
RanitidineThe serum concentration of Ranitidine can be increased when it is combined with Verapamil.
RanolazineThe serum concentration of Ranolazine can be increased when it is combined with Verapamil.
RegorafenibRegorafenib may increase the bradycardic activities of Verapamil.
ReserpineThe serum concentration of Verapamil can be increased when it is combined with Reserpine.
RifabutinThe serum concentration of Verapamil can be decreased when it is combined with Rifabutin.
RifampicinThe serum concentration of Verapamil can be decreased when it is combined with Rifampicin.
RifapentineThe serum concentration of Verapamil can be decreased when it is combined with Rifapentine.
RifaximinThe serum concentration of Rifaximin can be increased when it is combined with Verapamil.
RiociguatThe serum concentration of Riociguat can be increased when it is combined with Verapamil.
RisperidoneThe serum concentration of Risperidone can be increased when it is combined with Verapamil.
RitonavirThe serum concentration of Ritonavir can be increased when it is combined with Verapamil.
RituximabVerapamil may increase the hypotensive activities of Rituximab.
RivaroxabanThe serum concentration of Rivaroxaban can be increased when it is combined with Verapamil.
RocuroniumVerapamil may increase the neuromuscular blocking activities of Rocuronium.
RolapitantThe serum concentration of Verapamil can be increased when it is combined with Rolapitant.
RuxolitinibRuxolitinib may increase the bradycardic activities of Verapamil.
Salicylate-sodiumVerapamil may increase the anticoagulant activities of Salicylate-sodium.
SalmeterolThe serum concentration of Salmeterol can be increased when it is combined with Verapamil.
SaquinavirThe serum concentration of Verapamil can be increased when it is combined with Saquinavir.
SaxagliptinThe serum concentration of Saxagliptin can be increased when it is combined with Verapamil.
SecobarbitalThe metabolism of Verapamil can be increased when combined with Secobarbital.
SilodosinThe serum concentration of Silodosin can be increased when it is combined with Verapamil.
SiltuximabThe serum concentration of Verapamil can be decreased when it is combined with Siltuximab.
SimeprevirThe serum concentration of Simeprevir can be increased when it is combined with Verapamil.
SimvastatinThe serum concentration of Simvastatin can be increased when it is combined with Verapamil.
SirolimusThe serum concentration of Sirolimus can be increased when it is combined with Verapamil.
SitagliptinThe serum concentration of Sitagliptin can be increased when it is combined with Verapamil.
SofosbuvirThe serum concentration of Sofosbuvir can be increased when it is combined with Verapamil.
SonidegibThe serum concentration of Sonidegib can be increased when it is combined with Verapamil.
St. John's WortThe serum concentration of Verapamil can be decreased when it is combined with St. John's Wort.
StiripentolThe serum concentration of Verapamil can be increased when it is combined with Stiripentol.
SufentanilSufentanil may increase the bradycardic activities of Verapamil.
SulfisoxazoleThe serum concentration of Verapamil can be increased when it is combined with Sulfisoxazole.
SunitinibThe serum concentration of Verapamil can be increased when it is combined with Sunitinib.
SuvorexantThe serum concentration of Suvorexant can be increased when it is combined with Verapamil.
TacrolimusThe metabolism of Tacrolimus can be decreased when combined with Verapamil.
TadalafilTadalafil may increase the antihypertensive activities of Verapamil.
TamoxifenThe serum concentration of Verapamil can be increased when it is combined with Tamoxifen.
TamsulosinTamsulosin may increase the hypotensive activities of Verapamil.
TelaprevirThe serum concentration of Telaprevir can be increased when it is combined with Verapamil.
TelithromycinTelithromycin may increase the bradycardic activities of Verapamil.
TemsirolimusThe serum concentration of Temsirolimus can be increased when it is combined with Verapamil.
TeniposideThe serum concentration of Teniposide can be increased when it is combined with Verapamil.
TerazosinTerazosin may increase the hypotensive activities of Verapamil.
TesmilifeneThe serum concentration of Verapamil can be decreased when it is combined with Tesmilifene.
TipranavirThe serum concentration of Verapamil can be decreased when it is combined with Tipranavir.
TizanidineThe serum concentration of Tizanidine can be increased when it is combined with Verapamil.
TocilizumabThe serum concentration of Verapamil can be decreased when it is combined with Tocilizumab.
TofacitinibTofacitinib may increase the bradycardic activities of Verapamil.
TolvaptanThe serum concentration of Tolvaptan can be increased when it is combined with Verapamil.
TopotecanThe serum concentration of Topotecan can be increased when it is combined with Verapamil.
TrabectedinThe serum concentration of Trabectedin can be increased when it is combined with Verapamil.
TranylcypromineTranylcypromine may increase the hypotensive activities of Verapamil.
TreprostinilTreprostinil may increase the hypotensive activities of Verapamil.
UlipristalThe serum concentration of Ulipristal can be increased when it is combined with Verapamil.
ValsartanThe risk or severity of adverse effects can be increased when Valsartan is combined with Verapamil.
VandetanibThe serum concentration of Verapamil can be increased when it is combined with Vandetanib.
VardenafilVardenafil may increase the antihypertensive activities of Verapamil.
VecuroniumVerapamil may increase the neuromuscular blocking activities of Vecuronium.
VemurafenibThe serum concentration of Vemurafenib can be increased when it is combined with Verapamil.
VilazodoneThe serum concentration of Vilazodone can be increased when it is combined with Verapamil.
VinblastineThe serum concentration of Vinblastine can be increased when it is combined with Verapamil.
VincristineThe serum concentration of Vincristine can be increased when it is combined with Verapamil.
VindesineThe serum concentration of Vindesine can be increased when it is combined with Verapamil.
VoriconazoleThe risk or severity of adverse effects can be increased when Voriconazole is combined with Verapamil.
YohimbineYohimbine may decrease the antihypertensive activities of Verapamil.
ZopicloneThe serum concentration of Zopiclone can be increased when it is combined with Verapamil.
ZuclopenthixolThe serum concentration of Zuclopenthixol can be increased when it is combined with Verapamil.

Food Interactions:
  • Avoid alcohol.
  • Avoid excessive quantities of coffee or tea (Caffeine).
  • Avoid natural licorice.
  • Avoid taking with grapefruit juice.
  • Take with food.

Taxonomy

Kingdom: Organic compounds
Super Class: Not Available
Class: Not Available
Sub Class: Not Available
Direct Parent: Not Available
Alternative Parents:
  • Alkyl aryl ethers
  • Anisoles
  • Aralkylamines
  • Benzyl cyanides
  • Dimethoxybenzenes
  • Hydrocarbon derivatives
  • Nitriles
  • Phenethylamines
  • Phenylpropanes
  • Trialkylamines

substituent:
  • Alkyl aryl ether
  • Amine
  • Anisole
  • Aralkylamine
  • Aromatic homomonocyclic compound
  • Benzyl-cyanide
  • Carbonitrile
  • Dimethoxybenzene
  • Ether
  • Hydrocarbon derivative
  • Methoxybenzene
  • Nitrile
  • O-dimethoxybenzene
  • Organonitrogen compound
  • Organooxygen compound
  • Phenethylamine
  • Phenol ether
  • Phenylbutylamine
  • Phenylpropane
  • Tertiary aliphatic amine
  • Tertiary amine

References

Synthesis Reference: Philippe Baudier, Arthur De Boeck, Jacques Fossion, "Novel galenic forms of verapamil, their preparation and medicines containing said novel galenic forms." U.S. Patent US4859469, issued April, 1987.
General Reference: # Bellamy WT: P-glycoproteins and multidrug resistance. Annu Rev Pharmacol Toxicol. 1996;36:161-83. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/8725386
External Links:
ResourceLink
RxListhttp://www.rxlist.com/cgi/generic/verapsr.htm
Drugs.comhttp://www.drugs.com/verapamil.html

ATC Codes:
  • Array

AHFS Codes:
  • 24:28.92

MSDS: Download
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