Detail

Venlafaxine

Description

Name: Venlafaxine
Type: small molecule
Groups: approved
Indication: For the management of major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder (social phobia), panic disorder with or without agoraphobia, vasomotor symptoms in women with breast cancer and in postmenopausal women, and neuropathic pain.
Accession Number: DB00285 ( APRD00125)
Description: Venlafaxine (Effexor) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class first introduced by Wyeth in 1993. It is prescribed for the treatment of clinical depression and anxiety disorders. Due to the pronounced side effects and suspicions that venlafaxine may significantly increase the risk of suicide it is not recommended as a first line treatment of depression. However, it is often effective for depression not responding to SSRIs. Venlafaxine was the sixth most widely-used antidepressant based on the amount of retail prescriptions in the US (17.1 million) in 2006. [Wikipedia]
Structure:
Prescription Products:
NameDosageStrengthRouteMarketing StartMarketing EndCountry
Act Venlafaxine XRcapsule (extended release)37.5 mgoral13-02-2008Canada
Act Venlafaxine XRcapsule (extended release)75.0 mgoral13-02-2008Canada
Act Venlafaxine XRcapsule (extended release)150.0 mgoral13-02-2008Canada
Dom-venlafaxine XRcapsule (extended release)37.5 mgoral23-05-2013Canada
Dom-venlafaxine XRcapsule (extended release)75 mgoral23-05-2013Canada
Dom-venlafaxine XRcapsule (extended release)150 mgoral30-05-2013Canada
Effexor Tablets, 37.5mgtablet37.5 mgoral31-12-199419-08-2004Canada
Effexor Tablets, 50mgtablet50 mgoral31-12-199519-08-2004Canada
Effexor Tablets, 75mgtablet75 mgoral31-12-199419-08-2004Canada
Effexor XRcapsule, extended release75 mg/1oral01-11-1997US
Effexor XRcapsule, extended release37.5 mg/1oral01-11-1997US
Effexor XRcapsule, extended release150 mg/1oral01-11-1997US
Effexor XRcapsule, extended release150 mg/1oral25-05-2011US
Effexor XRcapsule, extended release150 mg/1oral28-08-2001US
Effexor XRcapsule, extended release75 mg/1oral25-04-2003US
Effexor XRcapsule, extended release75 mg/1oral01-11-1997US
Effexor XRcapsule, extended release150 mg/1oral01-11-1997US
Effexor XRcapsule (extended release)37.5 mgoral04-03-1998Canada
Effexor XRcapsule, extended release37.5 mg/1oral01-11-1997US
Effexor XRcapsule (extended release)75 mgoral04-03-1998Canada
Effexor XRcapsule (extended release)150 mgoral04-03-1998Canada
Effexor XRcapsule, extended release37.5 mg/1oral07-04-2004US
Effexor XRcapsule, extended release75 mg/1oral01-11-1997US
Effexor XRcapsule, extended release37.5 mg/1oral01-11-1997US
Effexor XRcapsule, extended release75 mg/1oral01-11-1997US
Effexor XRcapsule, extended release150 mg/1oral01-11-1997US
Effexor XRcapsule, extended release75 mg/1oral31-01-2011US
Effexor XRcapsule, extended release150 mg/1oral01-11-1997US
Effexor XR Extended-releasecapsule, extended release37.5 mg/1oral01-11-1997US
Effexor XR Extended-releasecapsule, extended release75 mg/1oral01-11-1997US
Effexor XR Extended-releasecapsule, extended release150 mg/1oral01-11-1997US
Effexor XR Extended-releasecapsule, extended release150 mg/1oral01-11-1997US
Gd-venlafaxine XRcapsule (extended release)37.5 mgoral28-10-2011Canada
Gd-venlafaxine XRcapsule (extended release)75 mgoral28-10-2011Canada
Gd-venlafaxine XRcapsule (extended release)150 mgoral28-10-2011Canada
Mylan-venlafaxine XRcapsule (extended release)37.5 mgoral07-05-2008Canada
Mylan-venlafaxine XRcapsule (extended release)75 mgoral07-05-2008Canada
Mylan-venlafaxine XRcapsule (extended release)150 mgoral07-05-2008Canada
Ntp-venlafaxine XRcapsule (extended release)37.5 mgoral01-01-1970Canada
Ntp-venlafaxine XRcapsule (extended release)75 mgoral01-01-1970Canada
Ntp-venlafaxine XRcapsule (extended release)150 mgoral01-01-1970Canada
PHL-venlafaxine XRcapsule (extended release)37.5 mgoral01-01-1970Canada
PHL-venlafaxine XRcapsule (extended release)75 mgoral01-01-1970Canada
PHL-venlafaxine XRcapsule (extended release)150 mgoral01-01-1970Canada
PMS-venlafaxine XRcapsule (extended release)37.5 mgoral17-08-2007Canada
PMS-venlafaxine XRcapsule (extended release)75 mgoral17-08-2007Canada
PMS-venlafaxine XRcapsule (extended release)150 mgoral17-08-2007Canada
Ran-venlafaxine XRcapsule (extended release)37.5 mgoral17-02-2012Canada
Ran-venlafaxine XRcapsule (extended release)75 mgoral17-02-2012Canada
Ran-venlafaxine XRcapsule (extended release)150 mgoral16-02-2012Canada
Riva-venlafaxine XRcapsule (extended release)37.5 mgoral22-05-2008Canada
Riva-venlafaxine XRcapsule (extended release)75 mgoral22-05-2008Canada
Riva-venlafaxine XRcapsule (extended release)150 mgoral22-05-2008Canada
Sandoz Venlafaxine XRcapsule (extended release)37.5 mgoral09-05-2008Canada
Sandoz Venlafaxine XRcapsule (extended release)75.0 mgoral09-05-2008Canada
Sandoz Venlafaxine XRcapsule (extended release)150.0 mgoral09-05-2008Canada
Teva-venlafaxine XRcapsule (extended release)37.5 mgoral01-12-2006Canada
Teva-venlafaxine XRcapsule (extended release)75 mgoral01-12-2006Canada
Teva-venlafaxine XRcapsule (extended release)150 mgoral01-12-2006Canada
Venlafaxine Hydrochloridetablet, extended release37.5 mg/1oral29-04-2010US
Venlafaxine Hydrochloridetablet, extended release75 mg/1oral29-04-2010US
Venlafaxine Hydrochloridetablet, extended release150 mg/1oral29-04-2010US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral10-06-2011US
Venlafaxine Hydrochloridetablet, extended release225 mg/1oral29-04-2010US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral02-06-2011US
Venlafaxine Hydrochloridetablet, film coated, extended release37.5 mg/1oral30-09-2008US
Venlafaxine Hydrochloridetablet, film coated, extended release75 mg/1oral10-10-2008US
Venlafaxine Hydrochloridetablet, film coated, extended release150 mg/1oral10-10-2008US
Venlafaxine Hydrochloridetablet, film coated, extended release225 mg/1oral17-10-2008US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral10-06-2011US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral10-06-2011US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral10-06-2011US
Venlafaxine Hydrochloridetablet, extended release75 mg/1oral17-11-2011US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral08-05-2013US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral10-06-2011US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral10-06-2011US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral10-06-2011US
Venlafaxine Hydrochloridetablet, extended release225 mg/1oral29-04-2010US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral01-01-2014US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral18-04-2014US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral10-06-2011US
Venlafaxine Hydrochloridecapsule, delayed release75 mg/1oral01-01-2015US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral14-03-2012US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral02-06-2011US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral02-06-2011US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral02-06-2011US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral10-06-2011US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral10-06-2011US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral10-06-2011US
Venlafaxine Hydrochloridetablet, extended release37.5 mg/1oral11-06-2010US
Venlafaxine Hydrochloride Extended-release Capsulescapsule (extended release)37.5 mgoral01-01-1970Canada
Venlafaxine Hydrochloride Extended-release Capsulescapsule (extended release)75 mgoral01-01-1970Canada
Venlafaxine Hydrochloride Extended-release Capsulescapsule (extended release)150 mgoral01-01-1970Canada
Venlafaxine XRcapsule (extended release)37.5 mgoral10-06-2012Canada
Venlafaxine XRcapsule (extended release)75 mgoral10-06-2012Canada
Venlafaxine XRcapsule (extended release)150 mgoral10-06-2012Canada
Venlafaxine XRcapsule (extended release)37.5 mgoral27-07-2010Canada
Venlafaxine XRcapsule (extended release)75 mgoral27-07-2010Canada
Venlafaxine XRcapsule (extended release)150 mgoral27-07-2010Canada
Venlafaxine XRcapsule (extended release)37.5 mgoral01-01-1970Canada
Venlafaxine XRcapsule (extended release)75 mgoral01-01-1970Canada
Venlafaxine XRcapsule (extended release)150 mgoral01-01-1970Canada
Venlafaxine XRcapsule (extended release)37.5 mgoral01-01-1970Canada
Venlafaxine XRcapsule (extended release)75.0 mgoral01-01-1970Canada
Venlafaxine XRcapsule (extended release)150.0 mgoral01-01-1970Canada
Venlafaxine XRcapsule (extended release)37.5 mgoral02-08-2007Canada
Venlafaxine XRcapsule (extended release)75 mgoral02-08-2007Canada
Venlafaxine XRcapsule (extended release)150 mgoral02-08-2007Canada
Venlafaxine XRcapsule (extended release)37.5 mgoral01-01-1970Canada
Venlafaxine XRcapsule (extended release)75 mgoral01-01-1970Canada
Venlafaxine XRcapsule (extended release)150 mgoral01-01-1970Canada
Venlafaxine XRcapsule (extended release)37.5 mgoral03-02-2010Canada
Venlafaxine XRcapsule (extended release)75 mgoral03-02-2010Canada
Venlafaxine XRcapsule (extended release)150 mgoral03-02-2010Canada

Generic Prescription Products:
NameDosageStrengthRouteMarketing StartMarketing EndCountry
Apo-venlafaxine XRcapsule (extended release)37.5 mgoral16-04-2013Canada
Apo-venlafaxine XRcapsule (extended release)75.0 mgoral16-04-2013Canada
Apo-venlafaxine XRcapsule (extended release)150.0 mgoral16-04-2013Canada
Venlafaxinetablet37.5 mg/1oral13-06-2008US
Venlafaxinetablet75 mg/1oral13-06-2008US
Venlafaxinetablet37.5 mg/1oral15-07-2008US
Venlafaxinetablet75 mg/1oral15-07-2008US
Venlafaxinetablet100 mg/1oral19-02-2014US
Venlafaxinetablet25 mg/1oral21-12-2010US
Venlafaxinetablet37.5 mg/1oral21-12-2010US
Venlafaxinetablet50 mg/1oral21-12-2010US
Venlafaxinetablet75 mg/1oral21-12-2010US
Venlafaxinetablet100 mg/1oral21-12-2010US
Venlafaxinetablet100 mg/1oral25-11-2013US
Venlafaxinetablet25 mg/1oral25-11-2013US
Venlafaxinetablet37.5 mg/1oral25-11-2013US
Venlafaxinetablet50 mg/1oral25-11-2013US
Venlafaxinetablet75 mg/1oral25-11-2013US
Venlafaxinetablet75 mg/1oral01-01-2015US
Venlafaxinetablet25 mg/1oral13-06-2008US
Venlafaxinetablet37.5 mg/1oral13-06-2008US
Venlafaxinetablet50 mg/1oral13-06-2008US
Venlafaxinetablet25 mg/1oral21-12-2010US
Venlafaxinetablet75 mg/1oral13-06-2008US
Venlafaxinetablet37.5 mg/1oral21-12-2010US
Venlafaxinetablet50 mg/1oral13-06-2008US
Venlafaxinetablet50 mg/1oral21-12-2010US
Venlafaxinetablet100 mg/1oral13-06-2008US
Venlafaxinetablet75 mg/1oral21-12-2010US
Venlafaxinetablet100 mg/1oral21-12-2010US
Venlafaxinetablet75 mg/1oral01-01-2014US
Venlafaxinetablet37.5 mg/1oral30-11-2012US
Venlafaxinetablet75 mg/1oral30-11-2012US
Venlafaxinetablet25 mg/1oral13-06-2008US
Venlafaxinetablet37.5 mg/1oral13-06-2008US
Venlafaxinetablet50 mg/1oral13-06-2008US
Venlafaxinetablet75 mg/1oral13-06-2008US
Venlafaxinetablet100 mg/1oral13-06-2008US
Venlafaxinetablet50 mg/1oral30-11-2012US
Venlafaxinetablet75 mg/1oral25-01-2016US
Venlafaxinetablet75 mg/1oral01-01-2014US
Venlafaxinetablet75 mg/1oral13-06-2008US
Venlafaxinetablet100 mg/1oral13-06-2008US
Venlafaxinetablet50 mg/1oral01-01-2014US
Venlafaxinetablet25 mg/1oral07-04-2010US
Venlafaxinetablet37.5 mg/1oral07-04-2010US
Venlafaxinetablet50 mg/1oral07-04-2010US
Venlafaxinetablet25 mg/1oral01-10-2015US
Venlafaxinetablet75 mg/1oral07-04-2010US
Venlafaxinetablet37.5 mg/1oral01-10-2015US
Venlafaxinetablet100 mg/1oral07-04-2010US
Venlafaxinetablet50 mg/1oral01-10-2015US
Venlafaxinetablet75 mg/1oral01-10-2015US
Venlafaxinetablet100 mg/1oral01-10-2015US
Venlafaxinetablet25 mg/1oral03-09-2014US
Venlafaxinetablet50 mg/1oral03-09-2014US
Venlafaxinetablet75 mg/1oral08-10-2015US
Venlafaxinetablet100 mg/1oral03-09-2014US
Venlafaxinetablet25 mg/1oral08-10-2015US
Venlafaxinetablet100 mg/1oral09-10-2015US
Venlafaxinetablet37.5 mg/1oral19-10-2015US
Venlafaxinetablet37.5 mg/1oral01-01-2015US
Venlafaxinetablet37.5 mg/1oral15-02-2015US
Venlafaxinetablet50 mg/1oral27-10-2015US
Venlafaxinetablet75 mg/1oral13-06-2008US
Venlafaxinetablet75 mg/1oral15-02-2015US
Venlafaxinetablet25 mg/1oral30-11-2012US
Venlafaxinetablet37.5 mg/1oral30-11-2012US
Venlafaxinetablet50 mg/1oral30-11-2012US
Venlafaxinetablet75 mg/1oral30-11-2012US
Venlafaxinetablet25 mg/1oral15-02-2015US
Venlafaxinetablet100 mg/1oral30-11-2012US
Venlafaxinetablet50 mg/1oral04-08-2010US
Venlafaxinetablet75 mg/1oral04-08-2010US
Venlafaxinetablet100 mg/1oral04-08-2010US
Venlafaxinetablet25 mg/1oral04-08-2010US
Venlafaxinetablet50 mg/1oral15-02-2015US
Venlafaxinetablet37.5 mg/1oral04-08-2010US
Venlafaxinetablet100 mg/1oral15-02-2015US
Venlafaxinetablet50 mg/1oral04-08-2010US
Venlafaxinetablet75 mg/1oral04-08-2010US
Venlafaxinetablet100 mg/1oral04-08-2010US
Venlafaxinetablet25 mg/1oral04-08-2010US
Venlafaxinetablet37.5 mg/1oral04-08-2010US
Venlafaxinetablet25 mg/1oral07-04-2010US
Venlafaxinetablet37.5 mg/1oral07-04-2010US
Venlafaxinetablet50 mg/1oral07-04-2010US
Venlafaxinetablet75 mg/1oral07-04-2010US
Venlafaxinetablet100 mg/1oral07-04-2010US
Venlafaxine Hydrochloridetablet, extended release150 mg/1oral15-12-2014US
Venlafaxine Hydrochloridetablet, extended release75 mg/1oral15-12-2014US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral07-06-2011US
Venlafaxine Hydrochloridetablet, extended release37.5 mg/1oral15-12-2014US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral07-06-2011US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral07-06-2011US
Venlafaxine Hydrochloridetablet25 mg/1oral04-08-2006US
Venlafaxine Hydrochloridetablet75 mg/1oral13-06-2008US
Venlafaxine Hydrochloridetablet75 mg/1oral04-08-2010US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral01-06-2011US
Venlafaxine Hydrochloridetablet37.5 mg/1oral23-11-2010US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral23-11-2011US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral12-06-2013US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral27-07-2015US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral12-06-2013US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral07-07-2012US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral07-07-2012US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral01-06-2011US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral07-07-2012US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral01-06-201131-12-2015US
Venlafaxine Hydrochloridetablet75 mg/1oral30-01-2011US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral01-06-201131-12-2015US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral01-06-201131-12-2015US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral11-01-2016US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral06-01-2011US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral06-01-2011US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral06-01-2011US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral30-05-2015US
Venlafaxine Hydrochloridetablet100 mg/1oral22-04-2011US
Venlafaxine Hydrochloridetablet75 mg/1oral13-06-2008US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral04-08-2011US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral05-08-2011US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral01-06-2011US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral01-06-2011US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral03-02-2014US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral01-06-2011US
Venlafaxine Hydrochloridetablet25 mg/1oral13-06-2008US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral27-11-2014US
Venlafaxine Hydrochloridetablet37.5 mg/1oral13-06-2008US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral01-07-2010US
Venlafaxine Hydrochloridetablet37.5 mg/1oral11-03-2014US
Venlafaxine Hydrochloridetablet50 mg/1oral13-06-2008US
Venlafaxine Hydrochloridetablet75 mg/1oral13-06-2008US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral11-09-2015US
Venlafaxine Hydrochloridetablet100 mg/1oral13-06-2008US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral03-02-2014US
Venlafaxine Hydrochloridetablet25 mg/1oral11-03-2014US
Venlafaxine Hydrochloridetablet75 mg/1oral03-05-2013US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral03-02-2014US
Venlafaxine Hydrochloridetablet25 mg/1oral25-04-2011US
Venlafaxine Hydrochloridetablet100 mg/1oral24-03-2014US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral28-06-2010US
Venlafaxine Hydrochloridetablet25 mg/1oral05-01-2012US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral01-07-2010US
Venlafaxine Hydrochloridetablet50 mg/1oral05-01-2012US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral01-07-2010US
Venlafaxine Hydrochloridetablet100 mg/1oral05-01-2012US
Venlafaxine Hydrochloridetablet50 mg/1oral09-04-2014US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral01-06-2011US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral01-06-2011US
Venlafaxine Hydrochloridetablet37.5 mg/1oral01-01-2014US
Venlafaxine Hydrochloridetablet100 mg/1oral15-04-2014US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral01-07-2010US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral01-07-2010US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral01-07-2010US
Venlafaxine Hydrochloridetablet75 mg/1oral04-08-2006US
Venlafaxine Hydrochloridetablet, extended release75 mg/1oral06-12-2011US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral07-06-2011US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral01-07-2010US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral07-06-2011US
Venlafaxine Hydrochloridetablet, extended release150 mg/1oral18-08-2010US
Venlafaxine Hydrochloridetablet, extended release75 mg/1oral18-08-2010US
Venlafaxine Hydrochloridetablet, extended release37.5 mg/1oral18-08-2010US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral14-04-2011US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral14-04-2011US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral14-04-2011US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral01-06-2011US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral01-06-2011US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral01-06-2011US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral01-06-2011US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral01-06-2011US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral01-06-2011US
Venlafaxine Hydrochloridetablet25 mg/1oral04-08-2006US
Venlafaxine Hydrochloridetablet50 mg/1oral02-05-2011US
Venlafaxine Hydrochloridetablet37.5 mg/1oral04-08-2006US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral27-10-2014US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral27-10-2014US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral01-06-2011US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral01-06-2011US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral01-06-2011US
Venlafaxine Hydrochloridetablet37.5 mg/1oral13-01-2009US
Venlafaxine Hydrochloridetablet75 mg/1oral13-01-200930-06-2016US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral06-04-2015US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral06-04-2015US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral06-04-2015US
Venlafaxine Hydrochloridetablet25 mg/1oral20-02-2013US
Venlafaxine Hydrochloridetablet37.5 mg/1oral27-11-2009US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral01-07-2010US
Venlafaxine Hydrochloridetablet37.5 mg/1oral27-11-2009US
Venlafaxine Hydrochloridecapsule, coated, extended release75 mg/1oral01-01-2014US
Venlafaxine Hydrochloridetablet25 mg/1oral16-06-2008US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral01-06-2011US
Venlafaxine Hydrochloridetablet37.5 mg/1oral16-06-2008US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral01-06-2011US
Venlafaxine Hydrochloridetablet50 mg/1oral16-06-2008US
Venlafaxine Hydrochloridetablet25 mg/1oral13-06-2008US
Venlafaxine Hydrochloridetablet75 mg/1oral16-06-2008US
Venlafaxine Hydrochloridetablet100 mg/1oral16-06-2008US
Venlafaxine Hydrochloridetablet37.5 mg/1oral04-08-2006US
Venlafaxine Hydrochloridetablet50 mg/1oral04-08-2006US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral15-10-2012US
Venlafaxine Hydrochloridetablet75 mg/1oral04-08-2006US
Venlafaxine Hydrochloridetablet100 mg/1oral04-08-2006US
Venlafaxine Hydrochloridetablet37.5 mg/1oral04-08-2010US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral01-07-2010US
Venlafaxine Hydrochloridetablet75 mg/1oral04-08-2010US
Venlafaxine Hydrochloridetablet, extended release75 mg/1oral11-04-2013US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral01-07-2010US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral01-07-2010US
Venlafaxine Hydrochloridetablet25 mg/1oral03-09-2009US
Venlafaxine Hydrochloridetablet37.5 mg/1oral03-09-2009US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral01-07-2010US
Venlafaxine Hydrochloridetablet37.5 mg/1oral11-05-2010US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral12-06-2013US
Venlafaxine Hydrochloridetablet75 mg/1oral13-06-2008US
Venlafaxine Hydrochloridetablet75 mg/1oral03-09-2009US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral12-06-2013US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral28-06-2010US
Venlafaxine Hydrochloridetablet100 mg/1oral03-09-2009US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral12-06-2013US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral01-07-2010US
Venlafaxine Hydrochloridetablet25 mg/1oral07-05-2012US
Venlafaxine Hydrochloridetablet37.5 mg/1oral07-05-2012US
Venlafaxine Hydrochloridetablet75 mg/1oral13-06-2008US
Venlafaxine Hydrochloridetablet50 mg/1oral07-05-2012US
Venlafaxine Hydrochloridetablet75 mg/1oral07-05-2012US
Venlafaxine Hydrochloridetablet100 mg/1oral07-05-2012US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral10-07-2013US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral10-07-2013US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral10-07-2013US
Venlafaxine Hydrochloridetablet37.5 mg/1oral19-07-2007US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral14-04-2011US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral14-04-2011US
Venlafaxine Hydrochloridetablet25 mg/1oral11-05-2010US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral14-04-2011US
Venlafaxine Hydrochloridetablet37.5 mg/1oral11-05-2010US
Venlafaxine Hydrochloridetablet100 mg/1oral11-05-2010US
Venlafaxine Hydrochloridetablet50 mg/1oral11-05-2010US
Venlafaxine Hydrochloridetablet75 mg/1oral11-05-2010US
Venlafaxine Hydrochloridetablet25 mg/1oral14-06-2008US
Venlafaxine Hydrochloridetablet37.5 mg/1oral14-06-2008US
Venlafaxine Hydrochloridetablet50 mg/1oral14-06-2008US
Venlafaxine Hydrochloridetablet75 mg/1oral14-06-2008US
Venlafaxine Hydrochloridetablet100 mg/1oral14-06-2008US
Venlafaxine Hydrochloridetablet75 mg/1oral02-02-2007US
Venlafaxine Hydrochloridetablet75 mg/1oral14-05-2013US
Venlafaxine Hydrochloridetablet100 mg/1oral11-05-2010US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral08-11-2010US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral10-06-2011US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral02-08-2010US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral10-06-2011US
Venlafaxine Hydrochloridetablet100 mg/1oral13-06-2008US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral08-11-2010US
Venlafaxine Hydrochloridecapsule, extended release150 mg/1oral27-05-2014US
Venlafaxine Hydrochloridetablet75 mg/1oral07-05-2012US
Venlafaxine Hydrochloridetablet37.5 mg/1oral07-05-2012US
Venlafaxine Hydrochloridecapsule, extended release75 mg/1oral27-03-2015US
Venlafaxine Hydrochloridecapsule, extended release37.5 mg/1oral01-07-2010US

Over the Counter Products: Not Available
International Brands
  • No Brands

Brand Names
  • No Brands

Brand Mixtures
Brand NameIngredients
Effexor XRVenlafaxine
Effexor XRVenlafaxine
Effexor XRVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
Effexor XRVenlafaxine
Effexor XRVenlafaxine
Effexor XRVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
Effexor XR Extended-releaseVenlafaxine
Effexor XR Extended-releaseVenlafaxine
Effexor XR Extended-releaseVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Effexor XRVenlafaxine
Effexor XRVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Effexor XRVenlafaxine
Effexor XRVenlafaxine
Effexor XRVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Effexor XRVenlafaxine
Effexor XRVenlafaxine
Effexor XRVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Effexor XRVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Effexor XRVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Effexor XR Extended-releaseVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
Venlafaxine HydrochlorideVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
VenlafaxineVenlafaxine
Effexor XRVenlafaxine
Effexor XRVenlafaxine
Effexor XRVenlafaxine
Venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Teva-venlafaxine XRVenlafaxine
Teva-venlafaxine XRVenlafaxine
Teva-venlafaxine XRVenlafaxine
PMS-venlafaxine XRVenlafaxine
PMS-venlafaxine XRVenlafaxine
PMS-venlafaxine XRVenlafaxine
Dom-venlafaxine XRVenlafaxine
Dom-venlafaxine XRVenlafaxine
Dom-venlafaxine XRVenlafaxine
Act Venlafaxine XRVenlafaxine
Act Venlafaxine XRVenlafaxine
Act Venlafaxine XRVenlafaxine
Riva-venlafaxine XRVenlafaxine
Riva-venlafaxine XRVenlafaxine
Riva-venlafaxine XRVenlafaxine
Mylan-venlafaxine XRVenlafaxine
Mylan-venlafaxine XRVenlafaxine
Mylan-venlafaxine XRVenlafaxine
Sandoz Venlafaxine XRVenlafaxine
Sandoz Venlafaxine XRVenlafaxine
Sandoz Venlafaxine XRVenlafaxine
Apo-venlafaxine XRVenlafaxine
Apo-venlafaxine XRVenlafaxine
Apo-venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Gd-venlafaxine XRVenlafaxine
Gd-venlafaxine XRVenlafaxine
Gd-venlafaxine XRVenlafaxine
Ran-venlafaxine XRVenlafaxine
Ran-venlafaxine XRVenlafaxine
Ran-venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Effexor Tablets, 75mgVenlafaxine
Effexor Tablets, 37.5mgVenlafaxine
Effexor Tablets, 50mgVenlafaxine
PHL-venlafaxine XRVenlafaxine
PHL-venlafaxine XRVenlafaxine
PHL-venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Ntp-venlafaxine XRVenlafaxine
Ntp-venlafaxine XRVenlafaxine
Ntp-venlafaxine XRVenlafaxine
Venlafaxine Hydrochloride Extended-release CapsulesVenlafaxine
Venlafaxine Hydrochloride Extended-release CapsulesVenlafaxine
Venlafaxine Hydrochloride Extended-release CapsulesVenlafaxine
Venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
Venlafaxine XRVenlafaxine
VenlafaxineVenlafaxine
Venlafaxine HydrochlorideVenlafaxine

Categories
  • Antidepressive Agents
  • Serotonin/Norepinephrine Reuptake Inhibitors

Pharmacology

Indication: For the management of major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder (social phobia), panic disorder with or without agoraphobia, vasomotor symptoms in women with breast cancer and in postmenopausal women, and neuropathic pain.
Pharmacodynamics: Not Available
Mechanism of action: The exact mechanism of action of venlafaxine is unknown, but appears to be associated with the its potentiation of neurotransmitter activity in the CNS. Venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), inhibit the reuptake of both serotonin and norepinephrine with a potency greater for the 5-HT than for the NE reuptake process. Both venlafaxine and the ODV metabolite have weak inhibitory effects on the reuptake of dopamine but, unlike the tricyclics and similar to SSRIs, they are not active at histaminergic, muscarinic, or alpha(1)-adrenergic receptors.
Absorption: Venlafaxine is well absorbed. Food does not effect the absorption of venlafaxine or its subsequent metabolism into ODV. Bioavailability is 45% following oral administration. Time to steady state = 3 days.
Volume of distribution:
  • 7.5 ± 3.7 L/kg [venlafaxine]
  • 5.7 ± 1.8 L/kg [O-desmethylvenlafaxine(active metabolite)]

Protein binding: The degree of binding of venlafaxine to human plasma is 27% ± 2% at concentrations ranging from 2.5 to 2215 ng/mL. The degree of ODV binding to human plasma is 30% ± 12% at concentrations ranging from 100 to 500 ng/mL. Protein-binding-induced drug interactions with venlafaxine are not expected.
Metabolism: Not Available
Route of elimination: Renal elimination of venlafaxine and its metabolites is the primary route of excretion. Approximately 87% of a venlafaxine dose is recovered in the urine within 48 hours as either unchanged venlafaxine (5%), unconjugated ODV (29%), conjugated ODV (26%), or other minor inactive metabolites (27%).
Half life: 5 hours
Clearance: Not Available
Toxicity: Most patients overdosing with venlafaxine develop only mild symptoms. However, severe toxicity is reported with the most common symptoms being CNS depression, serotonin toxicity, seizure, or cardiac conduction abnormalities. Venlafaxine's toxicity appears to be higher than other SSRIs, with a fatal toxic dose closer to that of the tricyclic antidepressants than the SSRIs. Doses of 900 mg or more are likely to cause moderate toxicity. Deaths have been reported following large doses.
Affected organisms
  • Not Available

SNP Mediated Adverse Drug Reactions
  • Not Available

Pharmacoeconomics

Manufacturers:
  • Wyeth pharmaceuticals inc
  • Teva pharmaceuticals usa inc
  • Osmotica pharmaceutical corp
  • Actavis totowa llc
  • Amneal pharmaceuticals
  • Aurobindo pharma ltd
  • Caraco pharmaceutical laboratories ltd
  • Dr reddys laboratories ltd
  • Mylan pharmaceuticals inc
  • Pliva hrvatska doo
  • Sandoz inc
  • Vintage pharmaceuticals llc
  • Zydus pharmaceuticals usa inc
  • Wyeth

Packagers:
Dosage forms
FormRouteStrength
Capsule (extended release)oral150.0 mg
Capsule (extended release)oral75.0 mg
Tabletoral37.5 mg
Tabletoral50 mg
Tabletoral75 mg
Capsule (extended release)oral150 mg
Capsule (extended release)oral37.5 mg
Capsule (extended release)oral75 mg
Capsule, extended releaseoral150 mg/1
Capsule, extended releaseoral37.5 mg/1
Capsule, extended releaseoral75 mg/1
Capsule, coated, extended releaseoral75 mg/1
Capsule, delayed releaseoral75 mg/1
Tabletoral100 mg/1
Tabletoral25 mg/1
Tabletoral37.5 mg/1
Tabletoral50 mg/1
Tabletoral75 mg/1
Tablet, extended releaseoral150 mg/1
Tablet, extended releaseoral225 mg/1
Tablet, extended releaseoral37.5 mg/1
Tablet, extended releaseoral75 mg/1
Tablet, film coated, extended releaseoral150 mg/1
Tablet, film coated, extended releaseoral225 mg/1
Tablet, film coated, extended releaseoral37.5 mg/1
Tablet, film coated, extended releaseoral75 mg/1

Prices
Unit descriptionCostUnit
Effexor Xr 37.5 mg Extended-Release Capsule$1.02capsule
Apo-Venlafaxine Xr 75 mg Extended-Release Capsule$1.14capsule
Co Venlafaxine Xr 75 mg Extended-Release Capsule$1.14capsule
Mylan-Venlafaxine Xr 75 mg Extended-Release Capsule$1.14capsule
Novo-Venlafaxine Xr 75 mg Extended-Release Capsule$1.14capsule
Pms-Venlafaxine Xr 75 mg Extended-Release Capsule$1.14capsule
Ratio-Venlafaxine Xr 75 mg Extended-Release Capsule$1.14capsule
Sandoz Venlafaxine Xr 75 mg Extended-Release Capsule$1.14capsule
Apo-Venlafaxine Xr 150 mg Extended-Release Capsule$1.2capsule
Co Venlafaxine Xr 150 mg Extended-Release Capsule$1.2capsule
Mylan-Venlafaxine Xr 150 mg Extended-Release Capsule$1.2capsule
Novo-Venlafaxine Xr 150 mg Extended-Release Capsule$1.2capsule
Pms-Venlafaxine Xr 150 mg Extended-Release Capsule$1.2capsule
Ratio-Venlafaxine Xr 150 mg Extended-Release Capsule$1.2capsule
Sandoz Venlafaxine Xr 150 mg Extended-Release Capsule$1.2capsule
Venlafaxine hcl 25 mg tablet$1.98tablet
Venlafaxine hcl 37.5 mg tablet$2.04tablet
Effexor Xr 75 mg Extended-Release Capsule$2.05capsule
Venlafaxine hcl 50 mg tablet$2.1tablet
Effexor Xr 150 mg Extended-Release Capsule$2.16capsule
Venlafaxine hcl 75 mg tablet$2.23tablet
Venlafaxine hcl 100 mg tablet$2.36tablet
Effexor 25 mg tablet$2.4tablet
Effexor 37.5 mg tablet$2.5tablet
Effexor 50 mg tablet$2.6tablet
Effexor 75 mg tablet$2.7tablet
Effexor 100 mg tablet$2.92tablet
Venlafaxine HCl 75 mg 24 Hour tablet$4.42tablet
Effexor xr 37.5 mg capsule$4.63capsule
Venlafaxine HCl 150 mg 24 Hour tablet$4.72tablet
Effexor xr 75 mg capsule$4.76capsule
Effexor XR 75 mg 24 Hour Capsule$5.39capsule
Effexor xr 150 mg capsule$5.65capsule
Effexor XR 150 mg 24 Hour Capsule$5.87capsule
Effexor 30 25 mg tablet Bottle$74.82bottle
Effexor 30 75 mg tablet Bottle$87.83bottle
Venlafaxine HCl 30 37.5 mg 24 Hour tablet Bottle$114.46bottle
Effexor XR 30 37.5 mg 24 Hour Capsule Bottle$144.33bottle
Venlafaxine HCl 30 225 mg 24 Hour tablet Bottle$276.98bottle
Apo-Venlafaxine Xr 37.5 mg Extended-Release Capsule$0.57capsule
Co Venlafaxine Xr 37.5 mg Extended-Release Capsule$0.57capsule
Mylan-Venlafaxine Xr 37.5 mg Extended-Release Capsule$0.57capsule
Novo-Venlafaxine Xr 37.5 mg Extended-Release Capsule$0.57capsule
Pms-Venlafaxine Xr 37.5 mg Extended-Release Capsule$0.57capsule
Ratio-Venlafaxine Xr 37.5 mg Extended-Release Capsule$0.57capsule
Sandoz Venlafaxine Xr 37.5 mg Extended-Release Capsule$0.57capsule

Patents
CountryPatent NumberApprovedExpires (estimated)
2126305Canada2006-10-172014-06-20
2199778Canada2005-12-202017-03-12
5916923United States1993-06-282013-06-28
6274171United States1997-09-202017-09-20

Interactions

Drug Interactions
DrugInteraction
AbciximabVenlafaxine may increase the anticoagulant activities of Abciximab.
AbirateroneThe serum concentration of Venlafaxine can be increased when it is combined with Abiraterone.
AcenocoumarolThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Acenocoumarol.
AcepromazineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Acepromazine.
AcetophenazineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Acetophenazine.
Acetylsalicylic acidVenlafaxine may increase the antiplatelet activities of Acetylsalicylic acid.
AlteplaseVenlafaxine may increase the anticoagulant activities of Alteplase.
AmisulprideThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Amisulpride.
AnistreplaseVenlafaxine may increase the anticoagulant activities of Anistreplase.
ApixabanThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Apixaban.
AprepitantThe serum concentration of Venlafaxine can be increased when it is combined with Aprepitant.
AripiprazoleThe serum concentration of Aripiprazole can be increased when it is combined with Venlafaxine.
ArticaineVenlafaxine may increase the tachycardic activities of Articaine.
BenzquinamideThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Benzquinamide.
BexaroteneThe serum concentration of Venlafaxine can be decreased when it is combined with Bexarotene.
BosentanThe serum concentration of Venlafaxine can be decreased when it is combined with Bosentan.
BrimonidineVenlafaxine may decrease the antihypertensive activities of Brimonidine.
CaffeineVenlafaxine may increase the antiplatelet activities of Caffeine.
CarphenazineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Carphenazine.
ChlormezanoneThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Chlormezanone.
ChlorpromazineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Chlorpromazine.
ChlorprothixeneThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Chlorprothixene.
CitalopramVenlafaxine may increase the QTc-prolonging activities of Citalopram.
Citric AcidVenlafaxine may increase the anticoagulant activities of Citric Acid.
ClonidineVenlafaxine may decrease the antihypertensive activities of Clonidine.
ClozapineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Clozapine.
CollagenaseThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Collagenase.
ConivaptanThe serum concentration of Venlafaxine can be increased when it is combined with Conivaptan.
Dabigatran etexilateVenlafaxine may increase the anticoagulant activities of Dabigatran etexilate.
DabrafenibThe serum concentration of Venlafaxine can be decreased when it is combined with Dabrafenib.
DalteparinVenlafaxine may increase the anticoagulant activities of Dalteparin.
DapoxetineThe risk or severity of adverse effects can be increased when Dapoxetine is combined with Venlafaxine.
DasatinibDasatinib may increase the anticoagulant activities of Venlafaxine.
DeferasiroxThe serum concentration of Venlafaxine can be decreased when it is combined with Deferasirox.
Deoxycholic AcidThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Deoxycholic Acid.
DesmopressinVenlafaxine may increase the antiplatelet activities of Desmopressin.
DexmedetomidineVenlafaxine may decrease the antihypertensive activities of Dexmedetomidine.
DiclofenacVenlafaxine may increase the antiplatelet activities of Diclofenac.
DicoumarolThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Dicoumarol.
DiflunisalVenlafaxine may increase the antiplatelet activities of Diflunisal.
DihydrocodeineVenlafaxine may increase the antiplatelet activities of Dihydrocodeine.
DipivefrinVenlafaxine may decrease the antihypertensive activities of Dipivefrin.
DofetilideVenlafaxine may increase the QTc-prolonging activities of Dofetilide.
DopamineVenlafaxine may increase the tachycardic activities of Dopamine.
DroperidolThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Droperidol.
Edetic AcidVenlafaxine may increase the anticoagulant activities of Edetic Acid.
EnoxaparinVenlafaxine may increase the anticoagulant activities of Enoxaparin.
EphedrineVenlafaxine may increase the tachycardic activities of Ephedrine.
EpinephrineVenlafaxine may increase the tachycardic activities of Epinephrine.
EthanolThe risk or severity of adverse effects can be increased when Ethanol is combined with Venlafaxine.
Ethyl biscoumacetateVenlafaxine may increase the anticoagulant activities of Ethyl biscoumacetate.
EtodolacVenlafaxine may increase the antiplatelet activities of Etodolac.
FencamfamineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Fencamfamine.
FenoprofenVenlafaxine may increase the antiplatelet activities of Fenoprofen.
FloctafenineVenlafaxine may increase the antiplatelet activities of Floctafenine.
FluconazoleThe metabolism of Venlafaxine can be decreased when combined with Fluconazole.
FluoxetineThe metabolism of Venlafaxine can be decreased when combined with Fluoxetine.
FlupentixolThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Flupentixol.
FluphenazineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Fluphenazine.
FlurbiprofenVenlafaxine may increase the antiplatelet activities of Flurbiprofen.
FluspirileneThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Fluspirilene.
FluvoxamineThe risk or severity of adverse effects can be increased when Fluvoxamine is combined with Venlafaxine.
Fondaparinux sodiumVenlafaxine may increase the anticoagulant activities of Fondaparinux sodium.
FosaprepitantThe serum concentration of Venlafaxine can be increased when it is combined with Fosaprepitant.
Fusidic AcidThe serum concentration of Venlafaxine can be increased when it is combined with Fusidic Acid.
GlucosamineGlucosamine may increase the antiplatelet activities of Venlafaxine.
GoserelinVenlafaxine may increase the QTc-prolonging activities of Goserelin.
GranisetronGranisetron may increase the serotonergic activities of Venlafaxine.
GuanfacineVenlafaxine may decrease the antihypertensive activities of Guanfacine.
HaloperidolThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Haloperidol.
HeparinVenlafaxine may increase the anticoagulant activities of Heparin.
IbritumomabThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Ibritumomab.
IbrutinibThe risk or severity of adverse effects can be increased when Ibrutinib is combined with Venlafaxine.
IbuprofenVenlafaxine may increase the antiplatelet activities of Ibuprofen.
IdelalisibThe serum concentration of Venlafaxine can be increased when it is combined with Idelalisib.
IndinavirThe serum concentration of Indinavir can be decreased when it is combined with Venlafaxine.
IndomethacinVenlafaxine may increase the antiplatelet activities of Indomethacin.
IobenguaneThe therapeutic efficacy of Iobenguane can be decreased when used in combination with Venlafaxine.
Ioflupane I 123Venlafaxine may decrease effectiveness of Ioflupane I 123 as a diagnostic agent.
IsocarboxazidIsocarboxazid may increase the serotonergic activities of Venlafaxine.
IvacaftorThe serum concentration of Venlafaxine can be increased when it is combined with Ivacaftor.
KetoprofenVenlafaxine may increase the antiplatelet activities of Ketoprofen.
KetorolacVenlafaxine may increase the antiplatelet activities of Ketorolac.
LeuprolideVenlafaxine may increase the QTc-prolonging activities of Leuprolide.
LevonordefrinVenlafaxine may increase the tachycardic activities of Levonordefrin.
LimaprostLimaprost may increase the antiplatelet activities of Venlafaxine.
LinezolidLinezolid may increase the serotonergic activities of Venlafaxine.
LoxapineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Loxapine.
LuliconazoleThe serum concentration of Venlafaxine can be increased when it is combined with Luliconazole.
Mefenamic acidVenlafaxine may increase the antiplatelet activities of Mefenamic acid.
MeloxicamVenlafaxine may increase the antiplatelet activities of Meloxicam.
MepivacaineVenlafaxine may increase the tachycardic activities of Mepivacaine.
MesoridazineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Mesoridazine.
MethotrimeprazineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Methotrimeprazine.
MethyldopaVenlafaxine may decrease the antihypertensive activities of Methyldopa.
Methylene blueVenlafaxine may increase the serotonergic activities of Methylene blue.
MetoclopramideThe risk or severity of adverse effects can be increased when Metoclopramide is combined with Venlafaxine.
MifepristoneThe serum concentration of Venlafaxine can be increased when it is combined with Mifepristone.
MitotaneThe serum concentration of Venlafaxine can be decreased when it is combined with Mitotane.
MoclobemideMoclobemide may increase the serotonergic activities of Venlafaxine.
MolindoneThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Molindone.
NabumetoneVenlafaxine may increase the antiplatelet activities of Nabumetone.
NaproxenVenlafaxine may increase the antiplatelet activities of Naproxen.
NelfinavirThe metabolism of Venlafaxine can be decreased when combined with Nelfinavir.
NetupitantThe serum concentration of Venlafaxine can be increased when it is combined with Netupitant.
NorepinephrineVenlafaxine may increase the tachycardic activities of Norepinephrine.
ObinutuzumabThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Obinutuzumab.
OlanzapineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Olanzapine.
Omega-3 fatty acidsOmega-3 fatty acids may increase the antiplatelet activities of Venlafaxine.
OndansetronThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Ondansetron.
OxaprozinVenlafaxine may increase the antiplatelet activities of Oxaprozin.
PalbociclibThe serum concentration of Venlafaxine can be increased when it is combined with Palbociclib.
PaliperidoneThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Paliperidone.
PanobinostatThe serum concentration of Venlafaxine can be increased when it is combined with Panobinostat.
Peginterferon alfa-2bThe serum concentration of Venlafaxine can be decreased when it is combined with Peginterferon alfa-2b.
Pentosan PolysulfateThe risk or severity of adverse effects can be increased when Pentosan Polysulfate is combined with Venlafaxine.
PentoxifyllinePentoxifylline may increase the antiplatelet activities of Venlafaxine.
PerphenazineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Perphenazine.
PhenelzinePhenelzine may increase the serotonergic activities of Venlafaxine.
PhenindioneVenlafaxine may increase the anticoagulant activities of Phenindione.
PhenprocoumonVenlafaxine may increase the anticoagulant activities of Phenprocoumon.
PhenytoinThe metabolism of Venlafaxine can be increased when combined with Phenytoin.
PimozideThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Pimozide.
PiperacetazineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Piperacetazine.
PiroxicamVenlafaxine may increase the antiplatelet activities of Piroxicam.
ProcarbazineProcarbazine may increase the serotonergic activities of Venlafaxine.
ProchlorperazineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Prochlorperazine.
PromazineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Promazine.
PropafenoneThe serum concentration of Venlafaxine can be increased when it is combined with Propafenone.
PseudoephedrineVenlafaxine may increase the tachycardic activities of Pseudoephedrine.
QuetiapineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Quetiapine.
RacepinephrineVenlafaxine may increase the tachycardic activities of Racepinephrine.
RasagilineRasagiline may increase the serotonergic activities of Venlafaxine.
RemoxiprideThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Remoxipride.
ReserpineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Reserpine.
ReteplaseVenlafaxine may increase the anticoagulant activities of Reteplase.
RidogrelVenlafaxine may increase the anticoagulant activities of Ridogrel.
RisperidoneThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Risperidone.
RitonavirThe metabolism of Venlafaxine can be decreased when combined with Ritonavir.
RivaroxabanVenlafaxine may increase the anticoagulant activities of Rivaroxaban.
Salicylate-sodiumThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Salicylate-sodium.
SelegilineSelegiline may increase the serotonergic activities of Venlafaxine.
SertindoleThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Sertindole.
SiltuximabThe serum concentration of Venlafaxine can be decreased when it is combined with Siltuximab.
SimeprevirThe serum concentration of Venlafaxine can be increased when it is combined with Simeprevir.
St. John's WortThe serum concentration of Venlafaxine can be decreased when it is combined with St. John's Wort.
StiripentolThe serum concentration of Venlafaxine can be increased when it is combined with Stiripentol.
StreptokinaseVenlafaxine may increase the anticoagulant activities of Streptokinase.
SulindacVenlafaxine may increase the antiplatelet activities of Sulindac.
SulodexideVenlafaxine may increase the anticoagulant activities of Sulodexide.
SulpirideThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Sulpiride.
Tedizolid PhosphateTedizolid Phosphate may increase the serotonergic activities of Venlafaxine.
TenecteplaseVenlafaxine may increase the anticoagulant activities of Tenecteplase.
ThioridazineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Thioridazine.
ThiothixeneThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Thiothixene.
Tiaprofenic acidVenlafaxine may increase the antiplatelet activities of Tiaprofenic acid.
TiclopidineThe metabolism of Venlafaxine can be decreased when combined with Ticlopidine.
TizanidineVenlafaxine may decrease the antihypertensive activities of Tizanidine.
TocilizumabThe serum concentration of Venlafaxine can be decreased when it is combined with Tocilizumab.
TolmetinVenlafaxine may increase the antiplatelet activities of Tolmetin.
TositumomabThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Tositumomab.
TramadolThe risk or severity of adverse effects can be increased when Tramadol is combined with Venlafaxine.
TranylcypromineTranylcypromine may increase the serotonergic activities of Venlafaxine.
TrazodoneVenlafaxine may increase the serotonergic activities of Trazodone.
TreprostinilVenlafaxine may increase the anticoagulant activities of Treprostinil.
TrifluoperazineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Trifluoperazine.
TriflupromazineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Triflupromazine.
TriprolidineVenlafaxine may increase the tachycardic activities of Triprolidine.
UrokinaseVenlafaxine may increase the anticoagulant activities of Urokinase.
Vitamin EVitamin E may increase the antiplatelet activities of Venlafaxine.
VoriconazoleThe risk or severity of adverse effects can be increased when Voriconazole is combined with Venlafaxine.
WarfarinThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Warfarin.
ZiprasidoneThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Ziprasidone.
ZuclopenthixolThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Zuclopenthixol.

Food Interactions:
  • Avoid alcohol.
  • Avoid St.John's Wort.
  • Take with food.

Taxonomy

Kingdom: Organic compounds
Super Class: Not Available
Class: Not Available
Sub Class: Not Available
Direct Parent: Not Available
Alternative Parents:
  • 1,3-aminoalcohols
  • Alkyl aryl ethers
  • Anisoles
  • Aralkylamines
  • Cyclic alcohols and derivatives
  • Cyclohexanols
  • Hydrocarbon derivatives
  • Methoxybenzenes
  • Tertiary alcohols
  • Trialkylamines

substituent:
  • 1,3-aminoalcohol
  • Alcohol
  • Alkyl aryl ether
  • Amine
  • Anisole
  • Aralkylamine
  • Aromatic homomonocyclic compound
  • Cyclic alcohol
  • Cyclohexanol
  • Ether
  • Hydrocarbon derivative
  • Methoxybenzene
  • Organonitrogen compound
  • Organooxygen compound
  • Phenol ether
  • Phenylpropylamine
  • Tertiary alcohol
  • Tertiary aliphatic amine
  • Tertiary amine

References

Synthesis Reference: Thomas P. Jerussi, Chrisantha H. Senanayake, "Derivatives of (+)-venlafaxine and methods of preparing and using the same." U.S. Patent US6197828, issued June, 1994.
General Reference: # Golden RN, Nicholas L: Antidepressant efficacy of venlafaxine. Depress Anxiety. 2000;12 Suppl 1:45-9. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/11098413 # Thase ME, Clayton AH, Haight BR, Thompson AH, Modell JG, Johnston JA: A double-blind comparison between bupropion XL and venlafaxine XR: sexual functioning, antidepressant efficacy, and tolerability. J Clin Psychopharmacol. 2006 Oct;26(5):482-8. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/16974189 # Bielski RJ, Ventura D, Chang CC: A double-blind comparison of escitalopram and venlafaxine extended release in the treatment of major depressive disorder. J Clin Psychiatry. 2004 Sep;65(9):1190-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/15367045 # Rowbotham MC, Goli V, Kunz NR, Lei D: Venlafaxine extended release in the treatment of painful diabetic neuropathy: a double-blind, placebo-controlled study. Pain. 2004 Aug;110(3):697-706. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/15288411 # Ozyalcin SN, Talu GK, Kiziltan E, Yucel B, Ertas M, Disci R: The efficacy and safety of venlafaxine in the prophylaxis of migraine. Headache. 2005 Feb;45(2):144-52. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/15705120 # Whirl-Carrillo M, McDonagh EM, Hebert JM, Gong L, Sangkuhl K, Thorn CF, Altman RB, Klein TE: Pharmacogenomics knowledge for personalized medicine. Clin Pharmacol Ther. 2012 Oct;92(4):414-7. doi: 10.1038/clpt.2012.96. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/22992668 # Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/19515014
External Links:
ResourceLink
RxListhttp://www.rxlist.com/cgi/generic/venlafax.htm
PDRhealthhttp://www.pdrhealth.com/drugs/rx/rx-mono.aspx?contentFileName=eff1794.html&contentName=Effexor%20XR&contentId=277
Drugs.comhttp://www.drugs.com/venlafaxine.html

ATC Codes:
  • Array

AHFS Codes:
  • 28:16.04.92

MSDS: Download
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