Detail

Tamsulosin

Description

Name: Tamsulosin
Type: small molecule
Groups: Array
Indication: Used in the treatment of signs and symptoms of benign prostatic hyperplasia (reduction in urinary obstruction and relief of associated manifestations such as hesitancy, terminal dribbling of urine, interrupted or weak stream...etc.)
Accession Number: DB00706 ( APRD00036)
Description: Tamsulosin is a selective antagonist at alpha-1A and alpha-1B-adrenoceptors in the prostate, prostatic capsule, prostatic urethra, and bladder neck. At least three discrete alpha1-adrenoceptor subtypes have been identified: alpha-1A, alpha-1B and alpha-1D; their distribution differs between human organs and tissue. Approximately 70% of the alpha1-receptors in human prostate are of the alpha-1A subtype. Blockage of these receptors causes relaxation of smooth muscles in the bladder neck and prostate.
Structure:
Prescription Products:
NameDosageStrengthRouteMarketing StartMarketing EndCountry
Ava-tamsulosin CRtablet (extended-release)0.4 mgoral19-09-201121-08-2014Canada
Dutasteride and Tamsulosin HydrochloridecapsuleArrayoral18-11-2015US
Flomaxcapsule.4 mg/1oral28-08-2001US
Flomaxcapsule.4 mg/1oral03-06-1999US
Flomaxcapsule.4 mg/1oral13-05-2010US
Flomaxcapsule.4 mg/1oral12-09-1997US
Flomaxcapsule.4 mg/1oral12-09-1997US
Flomaxcapsule (sustained-release)0.4 mgoral19-06-199827-08-2009Canada
Flomaxcapsule.4 mg/1oral30-03-2011US
Flomaxcapsule.4 mg/1oral12-09-1997US
Flomaxcapsule.4 mg/1oral12-09-1997US
Flomaxcapsule.4 mg/1oral12-09-1997US
Flomax CRtablet (extended-release)0.4 mgoral11-10-2005Canada
Jalyncapsule (immediate and extended release)Arrayoral17-11-2011Canada
JalyncapsuleArrayoral02-05-2012US
JalyncapsuleArrayoral21-06-2010US
Jamp-tamsulosincapsule (sustained-release)0.4 mgoral16-06-201005-07-2012Canada
Mylan-tamsulosincapsule (extended release)0.4 mgoral16-08-2007Canada
Ran-tamsulosincapsule (sustained-release)0.4 mgoral15-08-200713-06-2012Canada
Ratio-tamsulosincapsule (sustained-release)0.4 mgoral27-04-2007Canada
Sandoz Tamsulosincapsule (sustained-release)0.4 mgoral16-05-2007Canada
Sandoz Tamsulosincapsule (sustained-release)0.4 mgoral19-03-2014Canada
Sandoz Tamsulosin CRtablet (extended-release)0.4 mgoral04-01-2011Canada
Tamsulosin CRtablet (extended-release)0.4 mgoral24-07-2014Canada
Tamsulosin CRtablet (extended-release)0.4 mgoral21-11-2013Canada
Tamsulosin CRtablet (extended-release)0.4 mgoral08-10-2014Canada
Teva-tamsulosincapsule (sustained-release)0.4 mgoral21-02-2007Canada
Teva-tamsulosin CRtablet (extended-release)0.4 mgoral04-09-2013Canada
Uflocapsule (sustained-release)0.4 mgoral01-01-1970Canada

Generic Prescription Products:
NameDosageStrengthRouteMarketing StartMarketing EndCountry
Apo-tamsulosin CRtablet (extended-release)0.4 mgoral09-02-2012Canada
Tamsulosin Hydrochloridecapsule.4 mg/1oral30-09-2013US
Tamsulosin Hydrochloridecapsule.4 mg/1oral07-10-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral15-07-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral20-07-2011US
Tamsulosin Hydrochloridecapsule.4 mg/1oral20-02-2013US
Tamsulosin Hydrochloridecapsule.4 mg/1oral07-10-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-201031-12-2015US
Tamsulosin Hydrochloridecapsule.4 mg/1oral07-10-201029-12-2015US
Tamsulosin Hydrochloridecapsule.4 mg/1oral30-04-2013US
Tamsulosin Hydrochloridecapsule.4 mg/1oral07-05-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-02-2015US
Tamsulosin Hydrochloridecapsule.4 mg/1oral07-10-2013US
Tamsulosin Hydrochloridecapsule.4 mg/1oral10-03-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral17-03-2014US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral29-04-2010US
Tamsulosin Hydrochloridecapsule, gelatin coated.4 mg/1oral10-05-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral09-04-2014US
Tamsulosin Hydrochloridecapsule.4 mg/1oral05-01-2015US
Tamsulosin Hydrochloridecapsule.4 mg/1oral15-07-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-02-2013US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral22-04-2013US
Tamsulosin Hydrochloridecapsule.4 mg/1oral07-10-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral17-01-2014US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral01-01-2013US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral15-07-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral08-05-2014US
Tamsulosin Hydrochloridecapsule.4 mg/1oral05-07-2013US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral15-07-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral15-07-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral02-03-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral25-07-2013US
Tamsulosin Hydrochloridecapsule.4 mg/1oral15-03-2013US
Tamsulosin Hydrochloridecapsule.4 mg/1oral28-07-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral01-08-2014US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral22-05-2013US
Tamsulosin Hydrochloridecapsule.4 mg/1oral07-05-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral31-03-2015US
Tamsulosin Hydrochloridecapsule.4 mg/1oral19-03-2013US
Tamsulosin Hydrochloridecapsule.4 mg/1oral25-11-2015US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral30-04-2013US
Tamsulosin Hydrochloridecapsule.4 mg/1oral18-05-2011US
Tamsulosin Hydrochloridecapsule.4 mg/1oral15-07-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral10-05-2013US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US
Tamsulosin Hydrochloridecapsule.4 mg/1oral27-04-2010US

Over the Counter Products: Not Available
International Brands
  • No Brands

Brand Names
  • No Brands

Brand Mixtures
Brand NameIngredients
Tamsulosin HydrochlorideTamsulosin
JalynDutasteride + Tamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
FlomaxTamsulosin
FlomaxTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Dutasteride and Tamsulosin HydrochlorideDutasteride + Tamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
FlomaxTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
FlomaxTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
FlomaxTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
FlomaxTamsulosin
FlomaxTamsulosin
Tamsulosin HydrochlorideTamsulosin
JalynDutasteride + Tamsulosin
FlomaxTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
FlomaxTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin
Flomax CRTamsulosin
Teva-tamsulosinTamsulosin
Ratio-tamsulosinTamsulosin
Sandoz TamsulosinTamsulosin
Mylan-tamsulosinTamsulosin
Sandoz TamsulosinTamsulosin
Sandoz Tamsulosin CRTamsulosin
Apo-tamsulosin CRTamsulosin
Teva-tamsulosin CRTamsulosin
JalynTamsulosin + Dutasteride
Tamsulosin CRTamsulosin
Tamsulosin CRTamsulosin
Tamsulosin CRTamsulosin
FlomaxTamsulosin
Ran-tamsulosinTamsulosin
Jamp-tamsulosinTamsulosin
Ava-tamsulosin CRTamsulosin
UfloTamsulosin
Tamsulosin HydrochlorideTamsulosin
Tamsulosin HydrochlorideTamsulosin

Categories
  • Adrenergic alpha-1 Receptor Antagonists

Pharmacology

Indication: Used in the treatment of signs and symptoms of benign prostatic hyperplasia (reduction in urinary obstruction and relief of associated manifestations such as hesitancy, terminal dribbling of urine, interrupted or weak stream...etc.)
Pharmacodynamics: Not Available
Mechanism of action: Tamsulosin is a selective antagonist at alpha-1A and alpha-1B-adrenoceptors in the prostate, prostatic capsule, prostatic urethra, and bladder neck. At least three discrete alpha1-adrenoceptor subtypes have been identified: alpha-1A, alpha-1B and alpha-1D; their distribution differs between human organs and tissue. Approximately 70% of the alpha1-receptors in human prostate are of the alpha-1A subtype. Blockage of these receptors causes relaxation of smooth muscles in the bladder neck and prostate, and thus decreases urinary outflow resistance in men.
Absorption: Absorption of tamsulosin HCI from capsules 0.4 mg is essentially complete (>90%) following oral administration under fasting conditions.
Volume of distribution:
  • 16 L [intravenous administration to ten healthy male adults]

Protein binding: 94%-99%
Metabolism: Not Available
Route of elimination: Tamsulosin hydrochloride is extensively metabolized by cytochrome P450 enzymes in the liver and less than 10% of the dose is excreted in urine unchanged. The metabolites of tamsulosin hydrochloride undergo extensive conjugation to glucuronide or sulfate prior to renal excretion. On administration of the radiolabeled dose of tamsulosin hydrochloride to four healthy volunteers, 97% of the administered radioactivity was recovered, with urine (76%) representing the primary route of excretion compared to feces (21%) over 168 hours.
Half life: 5-7 hours
Clearance: Not Available
Toxicity: LD50 = 650 mg/kg (in rats)
Affected organisms
  • Not Available

SNP Mediated Adverse Drug Reactions
  • Not Available

Pharmacoeconomics

Manufacturers:
  • Boehringer ingelheim pharmaceuticals inc
  • Impax laboratories inc
  • Mylan pharmaceuticals inc
  • Sandoz inc
  • Sun pharmaceutical industries ltd
  • Synthon pharmaceuticals inc
  • Teva pharmaceuticals usa
  • Wockhardt ltd
  • Zydus pharmaceuticals usa inc

Packagers:
Dosage forms
FormRouteStrength
Tablet (extended-release)oral0.4 mg
Capsuleoral
Capsule (immediate and extended release)oral
Capsule (extended release)oral0.4 mg
Capsuleoral.4 mg/1
Capsule, gelatin coatedoral.4 mg/1
Capsule (sustained-release)oral0.4 mg

Prices
Unit descriptionCostUnit
Tamsulosin hcl 0.4 mg capsule$4.3capsule
Flomax 0.4 mg capsule$4.71capsule
Novo-Tamsulosin 0.4 mg Sustained-Release Capsule$0.57capsule
Ran-Tamsulosin 0.4 mg Sustained-Release Capsule$0.57capsule
Ratio-Tamsulosin 0.4 mg Sustained-Release Capsule$0.57capsule
Sandoz Tamsulosin 0.4 mg Sustained-Release Capsule$0.57capsule
Tamsulosin 0.4 mg Sustained-Release Capsule$0.57capsule
Flomax Cr 0.4 mg Extended-Release Tablet$0.63tablet
Mylan-Tamsulosin 0.4 mg Sustained-Release Capsule$0.63capsule

Patents
CountryPatent NumberApprovedExpires (estimated)
2144077Canada2005-05-242013-09-10
2490299Canada2008-08-262023-12-24
4703063United States1993-04-272010-04-27

Interactions

Drug Interactions
DrugInteraction
AlfuzosinAlfuzosin may increase the antihypertensive activities of Tamsulosin.
AmlodipineTamsulosin may increase the hypotensive activities of Amlodipine.
AmrinoneTamsulosin may increase the hypotensive activities of Amrinone.
AprepitantThe serum concentration of Tamsulosin can be increased when it is combined with Aprepitant.
AtazanavirThe serum concentration of Tamsulosin can be increased when it is combined with Atazanavir.
BepridilTamsulosin may increase the hypotensive activities of Bepridil.
BexaroteneThe serum concentration of Tamsulosin can be decreased when it is combined with Bexarotene.
BoceprevirThe serum concentration of Tamsulosin can be increased when it is combined with Boceprevir.
BosentanThe serum concentration of Tamsulosin can be decreased when it is combined with Bosentan.
BupropionThe serum concentration of Tamsulosin can be increased when it is combined with Bupropion.
CeritinibThe serum concentration of Tamsulosin can be increased when it is combined with Ceritinib.
CimetidineThe serum concentration of Tamsulosin can be increased when it is combined with Cimetidine.
CinacalcetThe serum concentration of Tamsulosin can be increased when it is combined with Cinacalcet.
ClarithromycinThe serum concentration of Tamsulosin can be increased when it is combined with Clarithromycin.
CobicistatThe serum concentration of Tamsulosin can be increased when it is combined with Cobicistat.
CocaineThe serum concentration of Tamsulosin can be increased when it is combined with Cocaine.
ConivaptanThe serum concentration of Tamsulosin can be increased when it is combined with Conivaptan.
DabrafenibThe serum concentration of Tamsulosin can be decreased when it is combined with Dabrafenib.
DapoxetineDapoxetine may increase the orthostatic hypotensive activities of Tamsulosin.
DarunavirThe serum concentration of Tamsulosin can be increased when it is combined with Darunavir.
DasatinibThe serum concentration of Tamsulosin can be increased when it is combined with Dasatinib.
DeferasiroxThe serum concentration of Tamsulosin can be decreased when it is combined with Deferasirox.
DelavirdineThe serum concentration of Tamsulosin can be increased when it is combined with Delavirdine.
DipivefrinTamsulosin may decrease the vasoconstricting activities of Dipivefrin.
FelodipineTamsulosin may increase the hypotensive activities of Felodipine.
FluconazoleThe metabolism of Tamsulosin can be decreased when combined with Fluconazole.
FlunarizineTamsulosin may increase the hypotensive activities of Flunarizine.
FluoxetineThe serum concentration of Tamsulosin can be increased when it is combined with Fluoxetine.
FosaprepitantThe serum concentration of Tamsulosin can be increased when it is combined with Fosaprepitant.
Fusidic AcidThe serum concentration of Tamsulosin can be increased when it is combined with Fusidic Acid.
GabapentinTamsulosin may increase the hypotensive activities of Gabapentin.
IdelalisibThe serum concentration of Tamsulosin can be increased when it is combined with Idelalisib.
IndinavirThe serum concentration of Tamsulosin can be increased when it is combined with Indinavir.
IsradipineTamsulosin may increase the hypotensive activities of Isradipine.
ItraconazoleThe serum concentration of Tamsulosin can be increased when it is combined with Itraconazole.
IvacaftorThe serum concentration of Tamsulosin can be increased when it is combined with Ivacaftor.
KetoconazoleThe serum concentration of Tamsulosin can be increased when it is combined with Ketoconazole.
LamotrigineTamsulosin may increase the hypotensive activities of Lamotrigine.
LercanidipineTamsulosin may increase the hypotensive activities of Lercanidipine.
LuliconazoleThe serum concentration of Tamsulosin can be increased when it is combined with Luliconazole.
Magnesium SulfateTamsulosin may increase the hypotensive activities of Magnesium Sulfate.
MethotrimeprazineThe serum concentration of Tamsulosin can be increased when it is combined with Methotrimeprazine.
MidodrineTamsulosin may decrease the vasoconstricting activities of Midodrine.
MifepristoneThe serum concentration of Tamsulosin can be increased when it is combined with Mifepristone.
MitotaneThe serum concentration of Tamsulosin can be decreased when it is combined with Mitotane.
NadololNadolol may increase the orthostatic hypotensive activities of Tamsulosin.
NefazodoneThe serum concentration of Tamsulosin can be increased when it is combined with Nefazodone.
NelfinavirThe serum concentration of Tamsulosin can be increased when it is combined with Nelfinavir.
NetupitantThe serum concentration of Tamsulosin can be increased when it is combined with Netupitant.
NicardipineTamsulosin may increase the hypotensive activities of Nicardipine.
NimodipineTamsulosin may increase the hypotensive activities of Nimodipine.
NisoldipineTamsulosin may increase the hypotensive activities of Nisoldipine.
NitrendipineTamsulosin may increase the hypotensive activities of Nitrendipine.
PalbociclibThe serum concentration of Tamsulosin can be increased when it is combined with Palbociclib.
ParoxetineThe serum concentration of Tamsulosin can be increased when it is combined with Paroxetine.
PerhexilineTamsulosin may increase the hypotensive activities of Perhexiline.
PhenelzinePhenelzine may increase the orthostatic hypotensive activities of Tamsulosin.
PhenytoinThe metabolism of Tamsulosin can be increased when combined with Phenytoin.
PosaconazoleThe serum concentration of Tamsulosin can be increased when it is combined with Posaconazole.
PrazosinPrazosin may increase the antihypertensive activities of Tamsulosin.
PrenylamineTamsulosin may increase the hypotensive activities of Prenylamine.
QuinidineThe serum concentration of Tamsulosin can be increased when it is combined with Quinidine.
RisedronateTamsulosin may increase the hypotensive activities of Risedronate.
RitonavirThe serum concentration of Tamsulosin can be increased when it is combined with Ritonavir.
SaquinavirThe serum concentration of Tamsulosin can be increased when it is combined with Saquinavir.
SiltuximabThe serum concentration of Tamsulosin can be decreased when it is combined with Siltuximab.
SimeprevirThe serum concentration of Tamsulosin can be increased when it is combined with Simeprevir.
St. John's WortThe serum concentration of Tamsulosin can be decreased when it is combined with St. John's Wort.
StiripentolThe serum concentration of Tamsulosin can be increased when it is combined with Stiripentol.
TadalafilTadalafil may increase the hypotensive activities of Tamsulosin.
TelaprevirThe serum concentration of Tamsulosin can be increased when it is combined with Telaprevir.
TelithromycinThe serum concentration of Tamsulosin can be increased when it is combined with Telithromycin.
TerbinafineThe serum concentration of Tamsulosin can be increased when it is combined with Terbinafine.
ThioridazineThe serum concentration of Tamsulosin can be increased when it is combined with Thioridazine.
TipranavirThe serum concentration of Tamsulosin can be increased when it is combined with Tipranavir.
TocilizumabThe serum concentration of Tamsulosin can be decreased when it is combined with Tocilizumab.
TranylcypromineTranylcypromine may increase the orthostatic hypotensive activities of Tamsulosin.
VardenafilVardenafil may increase the hypotensive activities of Tamsulosin.
VerapamilTamsulosin may increase the hypotensive activities of Verapamil.
VoriconazoleThe serum concentration of Tamsulosin can be increased when it is combined with Voriconazole.

Food Interactions:
  • Take 30 minutes after a meal (always after the same meal). Taking the drug with food minimizes plasma levels variations.

Taxonomy

Kingdom: Organic compounds
Super Class: Not Available
Class: Not Available
Sub Class: Not Available
Direct Parent: Not Available
Alternative Parents:
  • Alkyl aryl ethers
  • Aminosulfonyl compounds
  • Anisoles
  • Aralkylamines
  • Benzenesulfonamides
  • Dialkylamines
  • Hydrocarbon derivatives
  • Methoxybenzenes
  • Phenylpropanes
  • Sulfonamides

substituent:
  • Alkyl aryl ether
  • Amine
  • Aminosulfonyl compound
  • Amphetamine or derivatives
  • Anisole
  • Aralkylamine
  • Aromatic homomonocyclic compound
  • Benzenesulfonamide
  • Ether
  • Hydrocarbon derivative
  • Methoxybenzene
  • Organonitrogen compound
  • Organooxygen compound
  • Organosulfur compound
  • Phenol ether
  • Phenylpropane
  • Secondary aliphatic amine
  • Secondary amine
  • Sulfonamide
  • Sulfonic acid derivative
  • Sulfonyl

References

Synthesis Reference: Hun Wang, Jun Park, Min Kwon, Ji Shim, Bong Lee, Hong Jeon, "Controlled release formulation of tamsulosin hydrochloride and preparation process thereof." U.S. Patent US20050100606, issued May 12, 2005.
General Reference: # Dunn CJ, Matheson A, Faulds DM: Tamsulosin: a review of its pharmacology and therapeutic efficacy in the management of lower urinary tract symptoms. Drugs Aging. 2002;19(2):135-61. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/11950378 # Lyseng-Williamson KA, Jarvis B, Wagstaff AJ: Tamsulosin: an update of its role in the management of lower urinary tract symptoms. Drugs. 2002;62(1):135-67. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/11790159 # Wilt TJ, Mac Donald R, Rutks I: Tamsulosin for benign prostatic hyperplasia. Cochrane Database Syst Rev. 2003;(1):CD002081. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/12535426
External Links:
ResourceLink
RxListhttp://www.rxlist.com/cgi/generic2/tamsul.htm
Drugs.comhttp://www.drugs.com/cdi/tamsulosin.html

ATC Codes:
  • Array

AHFS Codes:
  • 92:00.00

MSDS: Download

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