Detail

Quinine

Description

Name: Quinine
Type: small molecule
Groups: approved
Indication: For the treatment of malaria and leg cramps
Accession Number: DB00468 ( APRD00563)
Description: An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood. [PubChem]
Structure:
Prescription Products:
NameDosageStrengthRouteMarketing StartMarketing EndCountry
Jamp-quininecapsule200 mgoral16-09-2015Canada
Jamp-quininecapsule300 mgoral16-09-2015Canada
Pro-quinine - 200capsule200 mgoral03-07-2008Canada
Pro-quinine - 300capsule300 mgoral03-07-2008Canada
Qualaquincapsule324 mg/1oral12-08-2005US
Qualaquincapsule324 mg/1oral12-08-2005US
Qualaquincapsule324 mg/1oral12-08-2005US
Quinine - Odantablet300 mgoral08-11-2001Canada
Quinine - Odancapsule200 mgoral01-05-1999Canada
Quinine - Odancapsule300 mgoral01-05-1999Canada
Quinine Sulfatecapsule324 mg/1oral31-03-2015US
Quinine Sulfatecapsule300 mgoral01-01-1970Canada
Quinine Sulfatecapsule200 mgoral01-01-1970Canada
Quinine Sulfatecapsule324 mg/1oral23-07-2012US
Quinine Sulfate Cap 200mgcapsule200 mgoral31-12-195107-04-1998Canada
Quinine Sulfate Cap 200mgcapsule200 mgoral31-12-195720-07-2001Canada
Quinine Sulfate Cap 300mgcapsule300 mgoral31-12-195107-04-1998Canada
Quinine Sulfate Cap 300mgcapsule300 mgoral31-12-195720-07-2001Canada
Quinine Sulfate Capsules 200mgcapsule200 mgoral31-12-195123-04-2002Canada
Quinine Sulfate Capsules 300mgcapsule300 mgoral31-12-195123-04-2002Canada
Teva-quininecapsule200 mgoral31-12-1966Canada
Teva-quininecapsule300 mgoral31-12-1966Canada

Generic Prescription Products:
NameDosageStrengthRouteMarketing StartMarketing EndCountry
Apo-quinine Capsulescapsule200 mgoral08-06-2004Canada
Apo-quinine Capsulescapsule300 mgoral08-06-2004Canada
Quinine Sulfatecapsule324 mg/1oral04-08-2015US
Quinine Sulfatecapsule324 mg/1oral23-07-2015US
Quinine Sulfatecapsule324 mg/1oral28-09-2012US
Quinine Sulfatecapsule324 mg/1oral14-12-2012US
Quinine Sulfatecapsule324 mg/1oral23-07-2015US

Over the Counter Products: Not Available
International Brands
  • No Brands

Brand Names
  • No Brands

Brand Mixtures
Brand NameIngredients
Quinine SulfateQuinine
Quinine SulfateQuinine
QualaquinQuinine
QualaquinQuinine
QualaquinQuinine
Quinine SulfateQuinine
Quinine SulfateQuinine
Quinine SulfateQuinine
Quinine SulfateQuinine
Quinine SulfateQuinine
Teva-quinineQuinine
Quinine - OdanQuinine
Quinine - OdanQuinine
Quinine - OdanQuinine
Teva-quinineQuinine
Apo-quinine CapsulesQuinine
Apo-quinine CapsulesQuinine
Pro-quinine - 200Quinine
Pro-quinine - 300Quinine
Quinine Sulfate Capsules 300mgQuinine
Quinine Sulfate Cap 200mgQuinine
Quinine Sulfate Capsules 200mgQuinine
Quinine Sulfate Cap 200mgQuinine
Quinine Sulfate Cap 300mgQuinine
Quinine Sulfate Cap 300mgQuinine
Quinine SulfateQuinine
Quinine SulfateQuinine
Jamp-quinineQuinine
Jamp-quinineQuinine

Categories
  • Antimalarials
  • Analgesics, Non-Narcotic
  • Muscle Relaxants, Central
  • Herbs (Hypotensive Properties)

Pharmacology

Indication: For the treatment of malaria and leg cramps
Pharmacodynamics: Not Available
Mechanism of action: The theorized mechanism of action for quinine and related anti-malarial drugs is that these drugs are toxic to the malaria parasite. Specifically, the drugs interfere with the parasite's ability to break down and digest hemoglobin. Consequently, the parasite starves and/or builds up toxic levels of partially degraded hemoglobin in itself.
Absorption: 76 - 88%
Volume of distribution:
  • 1.43 ± 0.18 L/kg [Healthy Pediatric Controls]
  • 0.87 ± 0.12 L/kg [P. falciparum Malaria Pediatric Patients]
  • 2.5 to 7.1 L/kg [healthy subjects who received a single oral 600 mg dose]

Protein binding: Approximately 70%
Metabolism: Not Available
Route of elimination: Quinine is eliminated primarily via hepatic biotransformation. Approximately 20% of quinine is excreted unchanged in urine.
Half life: Approximately 18 hours
Clearance: Not Available
Toxicity: Quinine is a documented causative agent of drug induced thrombocytopenia (DIT). Thrombocytopenia is a low amount of platelets in the blood. Quinine induces production of antibodies against glycoprotein (GP) Ib-IX complex in the majority of cases of DIT, or more rarely, the platelet-glycoprotein complex GPIIb-IIIa. Increased antibodies against these complexes increases platelet clearance, leading to the observed thrombocytopenia.
Affected organisms
  • Not Available

SNP Mediated Adverse Drug Reactions
  • Not Available

Pharmacoeconomics

Manufacturers:
  • Ar holding co inc

Packagers:
Dosage forms
FormRouteStrength
Capsuleoral200 mg
Tabletoral300 mg
Capsuleoral324 mg/1
Capsuleoral300 mg

Prices
Unit descriptionCostUnit
Quinine sulfate powd ultrex$25.86g
Apo-Quinine 200 mg Capsule$0.25capsule
Novo-Quinine 200 mg Capsule$0.25capsule
Apo-Quinine 300 mg Capsule$0.39capsule
Novo-Quinine 300 mg Capsule$0.39capsule

Patents
CountryPatent NumberApprovedExpires (estimated)

Interactions

Drug Interactions
DrugInteraction
AcebutololQuinine may increase the hypotensive activities of Acebutolol.
AcenocoumarolQuinine may increase the anticoagulant activities of Acenocoumarol.
AcepromazineThe serum concentration of Acepromazine can be increased when it is combined with Quinine.
AcetohexamideAcetohexamide may increase the hypoglycemic activities of Quinine.
Acetylsalicylic acidAcetylsalicylic acid may increase the hypoglycemic activities of Quinine.
AfatinibThe serum concentration of Afatinib can be increased when it is combined with Quinine.
AliskirenQuinine may increase the hypotensive activities of Aliskiren.
AlogliptinAlogliptin may increase the hypoglycemic activities of Quinine.
Aluminum hydroxideThe serum concentration of Quinine can be decreased when it is combined with Aluminum hydroxide.
AmilorideQuinine may increase the hypotensive activities of Amiloride.
AminophyllineThe serum concentration of Aminophylline can be increased when it is combined with Quinine.
AmlodipineQuinine may increase the hypotensive activities of Amlodipine.
AmodiaquineThe serum concentration of Amodiaquine can be increased when it is combined with Quinine.
AprepitantThe serum concentration of Quinine can be increased when it is combined with Aprepitant.
ArtemetherThe risk or severity of adverse effects can be increased when Artemether is combined with Quinine.
AtenololQuinine may increase the hypotensive activities of Atenolol.
AtorvastatinThe serum concentration of Atorvastatin can be increased when it is combined with Quinine.
Atracurium besylateQuinine may increase the neuromuscular blocking activities of Atracurium besylate.
Azilsartan medoxomilQuinine may increase the hypotensive activities of Azilsartan medoxomil.
AzithromycinThe serum concentration of Quinine can be increased when it is combined with Azithromycin.
BenazeprilQuinine may increase the hypotensive activities of Benazepril.
BendroflumethiazideQuinine may increase the hypotensive activities of Bendroflumethiazide.
BetaxololQuinine may increase the hypotensive activities of Betaxolol.
BexaroteneThe serum concentration of Quinine can be decreased when it is combined with Bexarotene.
BisoprololQuinine may increase the hypotensive activities of Bisoprolol.
BosentanThe serum concentration of Quinine can be decreased when it is combined with Bosentan.
BosutinibThe serum concentration of Bosutinib can be increased when it is combined with Quinine.
Brentuximab vedotinThe serum concentration of Brentuximab vedotin can be increased when it is combined with Quinine.
BrexpiprazoleThe serum concentration of Brexpiprazole can be increased when it is combined with Quinine.
BumetanideQuinine may increase the hypotensive activities of Bumetanide.
Calcium AcetateThe serum concentration of Quinine can be increased when it is combined with Calcium Acetate.
Calcium carbonateThe serum concentration of Quinine can be decreased when it is combined with Calcium carbonate.
CanagliflozinCanagliflozin may increase the hypoglycemic activities of Quinine.
CandesartanQuinine may increase the hypotensive activities of Candesartan.
CaptoprilQuinine may increase the hypotensive activities of Captopril.
CarbamazepineThe serum concentration of Quinine can be decreased when it is combined with Carbamazepine.
CarvedilolThe serum concentration of Carvedilol can be increased when it is combined with Quinine.
ChlorothiazideQuinine may increase the hypotensive activities of Chlorothiazide.
ChlorpropamideChlorpropamide may increase the hypoglycemic activities of Quinine.
ChlorthalidoneQuinine may increase the hypotensive activities of Chlorthalidone.
CilazaprilQuinine may increase the hypotensive activities of Cilazapril.
CimetidineThe serum concentration of Quinine can be increased when it is combined with Cimetidine.
Cisatracurium besylateQuinine may increase the neuromuscular blocking activities of Cisatracurium besylate.
CitalopramCitalopram may increase the QTc-prolonging activities of Quinine.
ClarithromycinThe serum concentration of Quinine can be increased when it is combined with Clarithromycin.
ClevidipineQuinine may increase the hypotensive activities of Clevidipine.
ClonidineQuinine may increase the hypotensive activities of Clonidine.
CodeineThe therapeutic efficacy of Codeine can be decreased when used in combination with Quinine.
ColchicineThe serum concentration of Colchicine can be increased when it is combined with Quinine.
ConivaptanThe serum concentration of Quinine can be increased when it is combined with Conivaptan.
Dabigatran etexilateThe serum concentration of the active metabolites of Dabigatran etexilate can be increased when Dabigatran etexilate is used in combination with Quinine.
DabrafenibThe serum concentration of Quinine can be decreased when it is combined with Dabrafenib.
DapsoneThe risk or severity of adverse effects can be increased when Quinine is combined with Dapsone.
DeferasiroxThe serum concentration of Quinine can be decreased when it is combined with Deferasirox.
DicoumarolQuinine may increase the anticoagulant activities of Dicoumarol.
DigoxinThe serum concentration of Digoxin can be increased when it is combined with Quinine.
DihydrotestosteroneDihydrotestosterone may increase the hypoglycemic activities of Quinine.
DiltiazemQuinine may increase the hypotensive activities of Diltiazem.
DofetilideDofetilide may increase the QTc-prolonging activities of Quinine.
DoxazosinQuinine may increase the hypotensive activities of Doxazosin.
DoxorubicinThe serum concentration of Doxorubicin can be increased when it is combined with Quinine.
DronabinolThe serum concentration of Dronabinol can be increased when it is combined with Quinine.
DyphyllineThe serum concentration of Dyphylline can be increased when it is combined with Quinine.
EdoxabanThe serum concentration of Edoxaban can be increased when it is combined with Quinine.
EnalaprilQuinine may increase the hypotensive activities of Enalapril.
EnalaprilatQuinine may increase the hypotensive activities of Enalaprilat.
EplerenoneQuinine may increase the hypotensive activities of Eplerenone.
EprosartanQuinine may increase the hypotensive activities of Eprosartan.
ErythromycinThe serum concentration of Quinine can be increased when it is combined with Erythromycin.
EsmololQuinine may increase the hypotensive activities of Esmolol.
Ethacrynic acidQuinine may increase the hypotensive activities of Ethacrynic acid.
EverolimusThe serum concentration of Everolimus can be increased when it is combined with Quinine.
FelodipineQuinine may increase the hypotensive activities of Felodipine.
FesoterodineThe serum concentration of the active metabolites of Fesoterodine can be increased when Fesoterodine is used in combination with Quinine.
FluconazoleThe metabolism of Quinine can be decreased when combined with Fluconazole.
FluvoxamineThe metabolism of Fluvoxamine can be decreased when combined with Quinine.
FosaprepitantThe serum concentration of Quinine can be increased when it is combined with Fosaprepitant.
FosinoprilQuinine may increase the hypotensive activities of Fosinopril.
FosphenytoinThe serum concentration of Quinine can be decreased when it is combined with Fosphenytoin.
FurosemideQuinine may increase the hypotensive activities of Furosemide.
Fusidic AcidThe serum concentration of Quinine can be increased when it is combined with Fusidic Acid.
GliclazideGliclazide may increase the hypoglycemic activities of Quinine.
GlimepirideGlimepiride may increase the hypoglycemic activities of Quinine.
GliquidoneGliquidone may increase the hypoglycemic activities of Quinine.
GlyburideGlyburide may increase the hypoglycemic activities of Quinine.
GoserelinGoserelin may increase the QTc-prolonging activities of Quinine.
GuanfacineQuinine may increase the hypotensive activities of Guanfacine.
HalofantrineThe risk or severity of adverse effects can be increased when Quinine is combined with Halofantrine.
HydralazineQuinine may increase the hypotensive activities of Hydralazine.
HydrochlorothiazideQuinine may increase the hypotensive activities of Hydrochlorothiazide.
IdelalisibThe serum concentration of Quinine can be increased when it is combined with Idelalisib.
IndapamideQuinine may increase the hypotensive activities of Indapamide.
Insulin AspartInsulin Aspart may increase the hypoglycemic activities of Quinine.
Insulin DetemirInsulin Detemir may increase the hypoglycemic activities of Quinine.
Insulin GlargineInsulin Glargine may increase the hypoglycemic activities of Quinine.
Insulin GlulisineInsulin Glulisine may increase the hypoglycemic activities of Quinine.
Insulin LisproInsulin Lispro may increase the hypoglycemic activities of Quinine.
Insulin RegularInsulin Regular may increase the hypoglycemic activities of Quinine.
Insulin, isophaneInsulin, isophane may increase the hypoglycemic activities of Quinine.
IrbesartanQuinine may increase the hypotensive activities of Irbesartan.
IsradipineQuinine may increase the hypotensive activities of Isradipine.
IvabradineIvabradine may increase the QTc-prolonging activities of Quinine.
IvacaftorThe serum concentration of Quinine can be increased when it is combined with Ivacaftor.
LabetalolQuinine may increase the hypotensive activities of Labetalol.
LedipasvirThe serum concentration of Ledipasvir can be increased when it is combined with Quinine.
LeuprolideLeuprolide may increase the QTc-prolonging activities of Quinine.
LinagliptinLinagliptin may increase the hypoglycemic activities of Quinine.
LisinoprilQuinine may increase the hypotensive activities of Lisinopril.
LopinavirThe serum concentration of Quinine can be decreased when it is combined with Lopinavir.
LosartanQuinine may increase the hypotensive activities of Losartan.
LovastatinThe serum concentration of Lovastatin can be increased when it is combined with Quinine.
LuliconazoleThe serum concentration of Quinine can be increased when it is combined with Luliconazole.
LumefantrineThe risk or severity of adverse effects can be increased when Quinine is combined with Lumefantrine.
Magnesium hydroxideThe serum concentration of Quinine can be decreased when it is combined with Magnesium hydroxide.
Magnesium oxideThe serum concentration of Quinine can be decreased when it is combined with Magnesium oxide.
MannitolQuinine may increase the hypotensive activities of Mannitol.
MecamylamineQuinine may increase the hypotensive activities of Mecamylamine.
MefloquineThe risk or severity of adverse effects can be increased when Quinine is combined with Mefloquine.
MetforminMetformin may increase the hypoglycemic activities of Quinine.
MethyclothiazideQuinine may increase the hypotensive activities of Methyclothiazide.
MethyldopaQuinine may increase the hypotensive activities of Methyldopa.
MetolazoneQuinine may increase the hypotensive activities of Metolazone.
MetoprololQuinine may increase the hypotensive activities of Metoprolol.
MifepristoneMifepristone may increase the QTc-prolonging activities of Quinine.
MinoxidilQuinine may increase the hypotensive activities of Minoxidil.
MitotaneThe serum concentration of Quinine can be decreased when it is combined with Mitotane.
MoexiprilQuinine may increase the hypotensive activities of Moexipril.
MoxonidineQuinine may increase the hypotensive activities of Moxonidine.
NadololQuinine may increase the hypotensive activities of Nadolol.
NaloxegolThe serum concentration of Naloxegol can be increased when it is combined with Quinine.
NebivololThe serum concentration of Nebivolol can be increased when it is combined with Quinine.
NelfinavirThe metabolism of Quinine can be decreased when combined with Nelfinavir.
NetupitantThe serum concentration of Quinine can be increased when it is combined with Netupitant.
NicardipineQuinine may increase the hypotensive activities of Nicardipine.
NifedipineQuinine may increase the hypotensive activities of Nifedipine.
NimodipineQuinine may increase the hypotensive activities of Nimodipine.
NisoldipineQuinine may increase the hypotensive activities of Nisoldipine.
Nitric OxideThe risk or severity of adverse effects can be increased when Nitric Oxide is combined with Quinine.
NitroprussideQuinine may increase the hypotensive activities of Nitroprusside.
OctreotideOctreotide may increase the QTc-prolonging activities of Quinine.
OlmesartanQuinine may increase the hypotensive activities of Olmesartan.
OxandroloneOxandrolone may increase the hypoglycemic activities of Quinine.
PalbociclibThe serum concentration of Quinine can be increased when it is combined with Palbociclib.
PancuroniumQuinine may increase the neuromuscular blocking activities of Pancuronium.
ParoxetineParoxetine may increase the hypoglycemic activities of Quinine.
PazopanibThe serum concentration of Pazopanib can be increased when it is combined with Quinine.
PegvisomantPegvisomant may increase the hypoglycemic activities of Quinine.
PenbutololQuinine may increase the hypotensive activities of Penbutolol.
PerindoprilQuinine may increase the hypotensive activities of Perindopril.
PhenelzinePhenelzine may increase the hypoglycemic activities of Quinine.
PhenobarbitalThe serum concentration of Phenobarbital can be increased when it is combined with Quinine.
PhenoxybenzamineQuinine may increase the hypotensive activities of Phenoxybenzamine.
PhentolamineQuinine may increase the hypotensive activities of Phentolamine.
PhenytoinThe serum concentration of Quinine can be decreased when it is combined with Phenytoin.
PindololQuinine may increase the hypotensive activities of Pindolol.
PrazosinQuinine may increase the hypotensive activities of Prazosin.
PrilocaineThe risk or severity of adverse effects can be increased when Quinine is combined with Prilocaine.
PropranololQuinine may increase the hypotensive activities of Propranolol.
PrucaloprideThe serum concentration of Prucalopride can be increased when it is combined with Quinine.
QuinaprilQuinine may increase the hypotensive activities of Quinapril.
RamiprilQuinine may increase the hypotensive activities of Ramipril.
RepaglinideRepaglinide may increase the hypoglycemic activities of Quinine.
ReserpineQuinine may increase the hypotensive activities of Reserpine.
RifampicinThe serum concentration of Quinine can be decreased when it is combined with Rifampicin.
RifaximinThe serum concentration of Rifaximin can be increased when it is combined with Quinine.
RitonavirThe serum concentration of Quinine can be decreased when it is combined with Ritonavir.
RocuroniumQuinine may increase the neuromuscular blocking activities of Rocuronium.
Salicylate-sodiumSalicylate-sodium may increase the hypoglycemic activities of Quinine.
SaquinavirThe serum concentration of Quinine can be increased when it is combined with Saquinavir.
SaxagliptinSaxagliptin may increase the hypoglycemic activities of Quinine.
SildenafilThe metabolism of Sildenafil can be decreased when combined with Quinine.
SilodosinThe serum concentration of Silodosin can be increased when it is combined with Quinine.
SiltuximabThe serum concentration of Quinine can be decreased when it is combined with Siltuximab.
SimeprevirThe serum concentration of Quinine can be increased when it is combined with Simeprevir.
SimvastatinThe serum concentration of Simvastatin can be increased when it is combined with Quinine.
Sodium bicarbonateThe serum concentration of Quinine can be increased when it is combined with Sodium bicarbonate.
Sodium lactateThe serum concentration of Quinine can be increased when it is combined with Sodium lactate.
Sodium NitriteThe risk or severity of adverse effects can be increased when Quinine is combined with Sodium Nitrite.
SotalolQuinine may increase the hypotensive activities of Sotalol.
SparfloxacinSparfloxacin may increase the hypoglycemic activities of Quinine.
SpiramycinThe serum concentration of Quinine can be increased when it is combined with Spiramycin.
SpironolactoneQuinine may increase the hypotensive activities of Spironolactone.
St. John's WortThe serum concentration of Quinine can be decreased when it is combined with St. John's Wort.
StiripentolThe serum concentration of Quinine can be increased when it is combined with Stiripentol.
SuccinylcholineQuinine may increase the neuromuscular blocking activities of Succinylcholine.
TamoxifenThe serum concentration of the active metabolites of Tamoxifen can be reduced when Tamoxifen is used in combination with Quinine resulting in a loss in efficacy.
TelithromycinThe serum concentration of Quinine can be increased when it is combined with Telithromycin.
TelmisartanQuinine may increase the hypotensive activities of Telmisartan.
TerazosinQuinine may increase the hypotensive activities of Terazosin.
TesmilifeneThe serum concentration of Quinine can be decreased when it is combined with Tesmilifene.
TestosteroneTestosterone may increase the hypoglycemic activities of Quinine.
TetracyclineThe serum concentration of Quinine can be increased when it is combined with Tetracycline.
TheophyllineThe serum concentration of Theophylline can be increased when it is combined with Quinine.
ThioridazineThe serum concentration of Thioridazine can be increased when it is combined with Quinine.
TimololQuinine may increase the hypotensive activities of Timolol.
TocilizumabThe serum concentration of Quinine can be decreased when it is combined with Tocilizumab.
TolbutamideTolbutamide may increase the hypoglycemic activities of Quinine.
TopotecanThe serum concentration of Topotecan can be increased when it is combined with Quinine.
TorasemideQuinine may increase the hypotensive activities of Torasemide.
TramadolThe therapeutic efficacy of Tramadol can be decreased when used in combination with Quinine.
TrandolaprilQuinine may increase the hypotensive activities of Trandolapril.
TranylcypromineTranylcypromine may increase the hypoglycemic activities of Quinine.
TriamtereneQuinine may increase the hypotensive activities of Triamterene.
ValsartanQuinine may increase the hypotensive activities of Valsartan.
VecuroniumQuinine may increase the neuromuscular blocking activities of Vecuronium.
VerapamilThe serum concentration of Quinine can be increased when it is combined with Verapamil.
VildagliptinVildagliptin may increase the hypoglycemic activities of Quinine.
VincristineThe serum concentration of Vincristine can be increased when it is combined with Quinine.
WarfarinQuinine may increase the anticoagulant activities of Warfarin.

Food Interactions:
  • Take with food to reduce irritation.

Taxonomy

Kingdom: Organic compounds
Super Class: Not Available
Class: Not Available
Sub Class: Not Available
Direct Parent: Not Available
Alternative Parents:
  • 1,2-aminoalcohols
  • Alkyl aryl ethers
  • Anisoles
  • Aralkylamines
  • Aromatic alcohols
  • Azacyclic compounds
  • Heteroaromatic compounds
  • Hydrocarbon derivatives
  • Hydroxyquinolines
  • Piperidines
  • Pyridines and derivatives
  • Quinuclidines
  • Secondary alcohols
  • Trialkylamines

substituent:
  • 1,2-aminoalcohol
  • Alcohol
  • Alkyl aryl ether
  • Amine
  • Anisole
  • Aralkylamine
  • Aromatic alcohol
  • Aromatic heteropolycyclic compound
  • Azacycle
  • Benzenoid
  • Cinchonan-skeleton
  • Ether
  • Heteroaromatic compound
  • Hydrocarbon derivative
  • Hydroxyquinoline
  • Organoheterocyclic compound
  • Organonitrogen compound
  • Organooxygen compound
  • Piperidine
  • Pyridine
  • Quinoline
  • Quinuclidine
  • Secondary alcohol
  • Tertiary aliphatic amine
  • Tertiary amine

References

Synthesis Reference: Tong Sun, Shawn Watson, Wei Lai, Stephan D. Parent, "QUININE SULFATE/BISULFATE SOLID COMPLEX; METHODS OF MAKING; AND METHODS OF USE THEREOF." U.S. Patent US20090326005, issued December 31, 2009.
General Reference: # Paintaud G, Alvan G, Berninger E, Gustafsson LL, Idrizbegovic E, Karlsson KK, Wakelkamp M: The concentration-effect relationship of quinine-induced hearing impairment. Clin Pharmacol Ther. 1994 Mar;55(3):317-23. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/8143397
External Links:
ResourceLink
RxListhttp://www.rxlist.com/cgi/generic3/quinine.htm
Drugs.comhttp://www.drugs.com/cdi/quinine.html

ATC Codes:
  • Array

AHFS Codes:
  • 08:30.08
  • 92:02.00*

MSDS: Download

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