Detail

Paraldehyde

Description

Name: Paraldehyde
Type: small molecule
Groups: approved
Indication: Not Available
Accession Number: DB09117 ( DB09117)
Description: Paraldehyde is the cyclic trimer of acetaldehyde molecules. It was introduced into clinical practice in the UK by the Italian physician Vincenzo Cervello in 1882. It is a central nervous system depressant and was soon found to be an effective anticonvulsant, hypnotic and sedative. It was included in some cough medicines as an expectorant (though there is no known mechanism for this function beyond the placebo effect).
Structure:
Prescription Products:
NameDosageStrengthRouteMarketing StartMarketing EndCountry
Paraldehyde Inj Bp 100%liquid100 %intramuscular; intravenous31-12-199110-08-1999Canada
Paraldehyde Injection BPliquid100 %intramuscular; intravenous10-09-199814-03-2013Canada
Paraldehyde Injection BPliquid100 %intramuscular; intravenous08-02-2012Canada

Generic Prescription Products: Not Available
Over the Counter Products: Not Available
International Brands
  • No Brands

Brand Names
  • No Brands

Brand Mixtures
Brand NameIngredients
Paraldehyde Injection BPParaldehyde
Paraldehyde Inj Bp 100%Paraldehyde
Paraldehyde Injection BPParaldehyde

Categories
  • No Category

Pharmacology

Indication: Not Available
Pharmacodynamics: Not Available
Mechanism of action: Not Available
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half life: Not Available
Clearance: Not Available
Toxicity: Not Available
Affected organisms
  • Not Available

SNP Mediated Adverse Drug Reactions
  • Not Available

Pharmacoeconomics

Manufacturers:
  • Not Available

Packagers:
  • Not Available

Dosage forms
FormRouteStrength
Liquidintramuscular; intravenous100 %

Prices
Unit descriptionCostUnit

Patents
CountryPatent NumberApprovedExpires (estimated)

Interactions

Drug Interactions
DrugInteraction
AlfentanilAlfentanil may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
AlprazolamAlprazolam may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
AmitriptylineAmitriptyline may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
AmobarbitalAmobarbital may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
AmoxapineAmoxapine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
AripiprazoleAripiprazole may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
AsenapineAsenapine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
AzelastineAzelastine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
BaclofenBaclofen may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
BrexpiprazoleBrexpiprazole may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
BrimonidineBrimonidine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
BromazepamBromazepam may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
BrompheniramineBrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
BuprenorphineBuprenorphine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
BuspironeBuspirone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ButabarbitalButabarbital may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ButorphanolButorphanol may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
CarbamazepineCarbamazepine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
CarbinoxamineCarbinoxamine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
CarisoprodolCarisoprodol may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
CetirizineCetirizine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ChlordiazepoxideChlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ChlorphenamineChlorphenamine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ChlorpromazineChlorpromazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ChlorzoxazoneChlorzoxazone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ClemastineClemastine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ClobazamClobazam may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ClomipramineClomipramine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ClonazepamClonazepam may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ClonidineClonidine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ClorazepateClorazepate may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ClozapineClozapine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
CyclizineCyclizine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
CyclobenzaprineCyclobenzaprine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
CyproheptadineCyproheptadine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
DantroleneDantrolene may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
DesfluraneDesflurane may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
DesipramineDesipramine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
DesloratadineDesloratadine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Dexchlorpheniramine maleateDexchlorpheniramine maleate may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
DiazepamDiazepam may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
DimenhydrinateDimenhydrinate may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
DiphenhydramineDiphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
DisulfiramThe serum concentration of Paraldehyde can be increased when it is combined with Disulfiram.
DoxepinDoxepin may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
DoxylamineDoxylamine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
DronabinolDronabinol may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
DroperidolDroperidol may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
EfavirenzEfavirenz may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
EntacaponeEntacapone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
EstazolamEstazolam may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
EszopicloneEszopiclone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
EthanolEthanol may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
EthosuximideEthosuximide may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
EthotoinEthotoin may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
EzogabineEzogabine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
FelbamateFelbamate may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
FentanylFentanyl may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
FexofenadineFexofenadine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
FlibanserinFlibanserin may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
FlunarizineFlunarizine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
FlupentixolFlupentixol may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
FluphenazineFluphenazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
FlurazepamFlurazepam may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
FosphenytoinFosphenytoin may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
GabapentinGabapentin may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
gabapentin enacarbilgabapentin enacarbil may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Gamma Hydroxybutyric AcidGamma Hydroxybutyric Acid may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
GuanfacineGuanfacine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
HaloperidolHaloperidol may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
HydrocodoneHydrocodone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
HydromorphoneHydromorphone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
HydroxyzineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
IloperidoneIloperidone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ImipramineImipramine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
IsofluraneIsoflurane may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
KetamineKetamine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
LamotrigineLamotrigine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
LevetiracetamLevetiracetam may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
LevocabastineLevocabastine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
LevocetirizineLevocetirizine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
LevorphanolLevorphanol may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
LoratadineLoratadine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
LorazepamLorazepam may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
LoxapineLoxapine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
LurasidoneLurasidone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Magnesium SulfateMagnesium Sulfate may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
MaprotilineMaprotiline may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
MeclizineMeclizine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
MeprobamateMeprobamate may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
MetaxaloneMetaxalone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
MethadoneMethadone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
MethocarbamolMethocarbamol may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
MethohexitalMethohexital may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
MethotrimeprazineMethotrimeprazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
MethsuximideMethsuximide may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
MetyrosineParaldehyde may increase the sedative activities of Metyrosine.
MidazolamMidazolam may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
MinocyclineMinocycline may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
MirtazapineMirtazapine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
MorphineMorphine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
NabiloneNabilone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
NalbuphineNalbuphine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
NitrazepamNitrazepam may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Nitrous oxideNitrous oxide may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
NortriptylineNortriptyline may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
OlanzapineOlanzapine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
OlopatadineOlopatadine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
OrphenadrineOrphenadrine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
OxazepamOxazepam may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
OxycodoneOxycodone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
OxymorphoneOxymorphone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
PaliperidonePaliperidone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ParoxetineThe risk or severity of adverse effects can be increased when Paraldehyde is combined with Paroxetine.
PentazocinePentazocine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
PentobarbitalPentobarbital may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
PerampanelPerampanel may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
PerphenazinePerphenazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
PethidinePethidine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
PhenobarbitalPhenobarbital may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
PhenytoinPhenytoin may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
PimozidePimozide may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
PipotiazinePipotiazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
PizotifenPizotifen may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
PomalidomidePomalidomide may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
PramipexoleParaldehyde may increase the sedative activities of Pramipexole.
PregabalinPregabalin may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
PrimidonePrimidone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ProchlorperazineProchlorperazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
PromazinePromazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
PromethazinePromethazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
PropofolPropofol may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ProtriptylineProtriptyline may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
QuazepamQuazepam may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
QuetiapineQuetiapine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
RamelteonRamelteon may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
RemifentanilRemifentanil may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ReserpineReserpine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
RisperidoneRisperidone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
RopiniroleParaldehyde may increase the sedative activities of Ropinirole.
RotigotineParaldehyde may increase the sedative activities of Rotigotine.
RufinamideThe risk or severity of adverse effects can be increased when Rufinamide is combined with Paraldehyde.
ScopolamineScopolamine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Scopolamine butylbromideScopolamine butylbromide may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
SecobarbitalSecobarbital may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
SevofluraneSevoflurane may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Sodium oxybateSodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
StiripentolStiripentol may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
SufentanilSufentanil may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
SuvorexantSuvorexant may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
TapentadolTapentadol may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
TasimelteonTasimelteon may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
TemazepamTemazepam may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
TetrabenazineTetrabenazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ThalidomideThalidomide may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ThioridazineThioridazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ThiothixeneThiothixene may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
TiagabineTiagabine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
TizanidineTizanidine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
TolcaponeTolcapone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
TopiramateTopiramate may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
TramadolTramadol may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
TriazolamTriazolam may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
TrifluoperazineTrifluoperazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
TrimipramineTrimipramine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
TriprolidineTriprolidine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
VigabatrinVigabatrin may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ZaleplonZaleplon may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ZiconotideZiconotide may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ZiprasidoneZiprasidone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ZolpidemZolpidem may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ZonisamideZonisamide may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ZopicloneZopiclone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ZuclopenthixolZuclopenthixol may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.

Food Interactions:
  • Not Available

Taxonomy

Kingdom: Organic compounds
Super Class: Not Available
Class: Not Available
Sub Class: Not Available
Direct Parent: Not Available
Alternative Parents:
  • Acetals
  • Hydrocarbon derivatives
  • Oxacyclic compounds

substituent:
  • 1,3,5-trioxane
  • Acetal
  • Aliphatic heteromonocyclic compound
  • Hydrocarbon derivative
  • Organooxygen compound
  • Oxacycle

References

Synthesis Reference: Not Available
General Reference: Not Available
External Links:
ResourceLink

ATC Codes:
  • Array

AHFS Codes:
  • Not Available

MSDS: Download
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