Detail

Magaldrate

Description

Name: Magaldrate
Type: small molecule
Groups: withdrawn
Indication: Not Available
Accession Number: DB08938 ( DB08938)
Description: Magaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.
Structure:
Prescription Products: Not Available
Generic Prescription Products: Not Available
Over the Counter Products:
NameDosageStrengthRouteMarketing StartMarketing EndCountry
Riopan Chewable Tablets 480mgtablet480 mgoral31-12-199431-07-2002Canada
Riopan Sus 480mg/5mlsuspension480 mgoral31-12-199319-07-2002Canada
Riopan Suspension 480mg/5mlsuspension480 mgoral31-12-199431-07-2002Canada
Riopan Tab 480mgtablet480 mgoral31-12-199319-07-2002Canada

International Brands
  • No Brands

Brand Names
  • No Brands

Brand Mixtures
Brand NameIngredients
Riopan Sus 480mg/5mlMagaldrate
Riopan Tab 480mgMagaldrate
Riopan Suspension 480mg/5mlMagaldrate
Riopan Chewable Tablets 480mgMagaldrate

Categories
  • No Category

Pharmacology

Indication: Not Available
Pharmacodynamics: Not Available
Mechanism of action: Not Available
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Aluminium oxide: absorbed Al ions are eliminated in the urine (0.1-0.5 mg of Al in aluminium-containing antacid is absorbed from standard daily doses of antacid) while insoluble or poorly absorbed Al salts in the intestines are excreted through the feces. Magnesium oxide: absorbed Mg ions (up to 30%) are eliminated in the urine, unabsorbed is excreted in the feces.
Half life: Not Available
Clearance: Not Available
Toxicity: Not Available
Affected organisms
  • Not Available

SNP Mediated Adverse Drug Reactions
  • Not Available

Pharmacoeconomics

Manufacturers:
  • Not Available

Packagers:
  • Not Available

Dosage forms
FormRouteStrength
Suspensionoral480 mg
Tabletoral480 mg

Prices
Unit descriptionCostUnit

Patents
CountryPatent NumberApprovedExpires (estimated)

Interactions

Drug Interactions
DrugInteraction

Food Interactions:
  • Not Available

Taxonomy

Kingdom: Not Available
Super Class: Not Available
Class: Not Available
Sub Class: Not Available
Direct Parent: Not Available
Alternative Parents:
  • Not Available

substituent:
  • Not Available

References

Synthesis Reference: U.S. Patent 2,923,660.
General Reference: # Kurtz W: [A layered lattice antacid with long-term effectiveness. Profile of action and safety exemplified by magaldrate]. Fortschr Med. 1993 Feb 28;111(6):93-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/8462913 # Varas Lorenzo MJ, Lopez Martinez A, Gordillo Bernal J, Mundet Surroca J: [Comparative study of 3 drugs (aceglutamide aluminum, zinc acexamate, and magaldrate) in the long-term maintenance treatment (1 year) of peptic ulcer]. Rev Esp Enferm Dig. 1991 Aug;80(2):91-4. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/1790087
External Links:
ResourceLink
Drugs.comhttp://www.drugs.com/international/magaldrate.html

ATC Codes:
  • Array

AHFS Codes:
  • Not Available

MSDS: Download
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