Detail

Epinephrine

Description

Name: Epinephrine
Type: small molecule
Groups: approved
Indication: Used to treat anaphylaxis and sepsis. Also one of the body's main adrenergic neurotransmitters.
Accession Number: DB00668 ( APRD00450, EXPT00496)
Description: The active sympathomimetic hormone from the adrenal medulla in most species. It stimulates both the alpha- and beta- adrenergic systems, causes systemic vasoconstriction and gastrointestinal relaxation, stimulates the heart, and dilates bronchi and cerebral vessels. It is used in asthma and cardiac failure and to delay absorption of local anesthetics. [PubChem]
Structure:
Prescription Products:
NameDosageStrengthRouteMarketing StartMarketing EndCountry
2% Lidocaine and Epinephrine 1:100,000 Injection USPliquidArrayblock/infiltration01-12-2008Canada
4% Astracaine Dental With Epinephrine 1:200,000 (0.005mg/ml)solutionArrayblock/infiltration26-02-199728-11-2003Canada
4% Astracaine Dental With Epinephrine 1:200,000 (0.005mg/ml)solutionArrayblock/infiltration29-01-2004Canada
4% Astracaine Dental With Epinephrine Forte 1:100,000 (0.01mg/ml)solutionArrayblock/infiltration26-02-199728-11-2003Canada
4% Astracaine Dental With Epinephrine Forte 1:100,000 (0.01mg/ml)solutionArrayblock/infiltration29-01-2004Canada
4% Citanest Forte Dental With Epinephrine 1:200,000liquidArrayblock/infiltration18-01-2011Canada
Adrenaclickinjection.15 mg/.15mLsubcutaneous25-11-2009US
Adrenaclickinjection.3 mg/.3mLsubcutaneous25-11-2009US
Adrenaclick 0.15mg Auto-injectorsolution0.15 mgintramuscular01-01-1970Canada
Adrenaclick 0.30mg Auto-injectorsolution0.30 mgintramuscular01-01-1970Canada
Adrenalininjection1 mg/mLintramuscular; intraocular; subcutaneous01-07-2013US
Adrenalininjection1 mg/mLintramuscular; subcutaneous01-03-2014US
Adrenalininjection1 mg/mLintramuscular25-03-2015US
Adrenalin Chloride Sol 1:1000solution1 mgnasal31-12-1951Canada
Adrenalin Chloride Sol 1:1000 Ampsolution1 mgintramuscular; intravenous; subcutaneous31-12-1951Canada
Allerjectsolution0.15 mgintramuscular11-12-2012Canada
Allerjectsolution0.3 mgintramuscular11-12-2012Canada
Ana-kit (2mg/tab Orl, 1mg/ml Liq Sc Im)liquid; tabletArrayintramuscular; oral; subcutaneous13-05-199705-09-2002Canada
Anakit Insect Sting Treatment Kitliquid; tabletArrayoral; parenteral (unspecified)31-12-196425-09-1998Canada
Anapensolution0.3 mgintramuscular23-11-2009Canada
Anapen Juniorsolution0.15 mgintramuscular23-11-2009Canada
Articadentinjection, solutionArraysubcutaneous03-04-2000US
Articadentinjection, solutionArraysubcutaneous03-04-2000US
Articaineinjection, solutionArraysubcutaneous22-12-2014US
Articaineinjection, solutionArraysubcutaneous22-12-2014US
Articaineinjection, solutionArraysubcutaneous22-06-2015US
Articaineinjection, solutionArraysubcutaneous04-12-2015US
Articaine Hydrochloride and Epinephrineinjection, solutionArraysubcutaneous28-01-2015US
Articaine Hydrochloride and Epinephrineinjection, solutionArraysubcutaneous28-01-2014US
Articaine Hydrochloride and Epinephrineinjection, solutionArraydental; infiltration01-04-2011US
Auvi-Qinjection.15 mg/1intramuscular; subcutaneous15-11-2012US
Auvi-Qinjection.3 mg/1intramuscular; subcutaneous15-11-2012US
Bronkaid Mistometer Aem 0.5%metered-dose aerosol0.5 %inhalation31-12-197315-07-1999Canada
Bupivacaine HCl 0.5% and Epinephrine 1:200,000 InjectionsolutionArrayblock/infiltration07-05-2012Canada
Bupivacaine Hydrochloride and Epinephrineinjection, solutionArraydental; infiltration03-10-1972US
Bupivacaine Hydrochloride and Epinephrineinjection, solutionArrayepidural; infiltration; intracaudal16-06-1988US
Bupivacaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration16-06-1988US
Bupivacaine Hydrochloride and Epinephrineinjection, solutionArrayepidural; intracaudal16-06-1988US
Bupivacaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration16-06-1988US
Bupivacaine Hydrochloride and EpinephrineinjectionArrayepidural; infiltration; intracaudal01-07-2010US
Bupivacaine Hydrochloride and Epinephrineinjection, solutionArrayepidural; infiltration; intracaudal16-06-1988US
Bupivacaine Hydrochloride and Epinephrineinjection, solutionArrayepidural; infiltration; intracaudal16-06-1988US
Citanest Forteinjection, solutionArraydental18-11-1965US
Dentsply 2% Lidocaine With Epinephrine 1:100,000solutionArrayblock/infiltration30-08-200119-07-2012Canada
Dentsply 2% Lidocaine With Epinephrine 1:50,000solutionArrayblock/infiltration31-12-195419-07-2012Canada
Dentsply 4% Prilocaine and Epinephrine Injection 1:200,000solutionArrayblock/infiltration31-12-196819-07-2012Canada
E-pilo 1 Ophthalmic SolutiondropsArrayophthalmic31-12-199627-01-1999Canada
E-pilo 2 Ophthalmic SolutiondropsArrayophthalmic11-02-199710-05-1999Canada
E-pilo 4 Ophthalmic SolutiondropsArrayophthalmic31-12-199513-07-1999Canada
E-pilo 6 Ophthalmic SolutiondropsArrayophthalmic11-02-199710-05-1999Canada
E-pilo-1 Oph SolndropsArrayophthalmic31-12-198809-09-1996Canada
E-pilo-2 Oph SolndropsArrayophthalmic31-12-198823-07-1997Canada
E-pilo-4 Oph SolndropsArrayophthalmic31-12-198809-09-1996Canada
E-pilo-6 Oph SolndropsArrayophthalmic31-12-198823-07-1997Canada
Ephinephrineinjection, solution.1 mg/mLintravenous01-08-2010US
Epi E-Z Pen - Liquid - 0.3mg/0.3mlliquid0.3 mgintramuscular15-07-199720-05-2010Canada
Epinephrineinjection, solution1 mg/mLsubcutaneous17-09-2015US
Epinephrineinjection, solution.1 mg/mLendotracheal; intracardiac; intravenous01-05-1985US
Epinephrineinjection, solution.1 mg/mLendotracheal; intracardiac; intravenous05-04-1985US
Epinephrineinjection, solution.1 mg/mLintravenous01-08-2010US
Epinephrineinjection.3 mg/1subcutaneous18-04-2011US
Epinephrineinjection, solution, concentrate1 mg/mLintravenous08-08-2014US
Epinephrineinjection, solution1 mg/mLintracardiac; intramuscular; intravenous; subcutaneous01-07-2010US
Epinephrineinjection, solution1 mg/mLintracardiac; intramuscular; intravenous; subcutaneous30-09-1990US
Epinephrineinjection, solution1 mg/mLintramuscular; intravenous; subcutaneous01-03-1994US
Epinephrineinjection, solution.1 mg/mLendotracheal; intracardiac; intravenous05-04-1985US
Epinephrineinjection, solution.1 mg/mLendotracheal; intracardiac; intravenous01-05-1985US
Epinephrineinjection, solution1 mg/mLintramuscular; subcutaneous08-09-2005US
Epinephrineinjection.3 mg/1subcutaneous31-03-2010US
Epinephrineinjection, solution1 mg/mLintramuscular; subcutaneous01-03-2010US
Epinephrineinjection, solution.1 mg/mLintracardiac; intravenous03-05-2010US
Epinephrineinjection, solution1 mg/mLintracardiac; intramuscular; intravenous; subcutaneous03-05-2010US
Epinephrineinjection.1 mg/mLintracardiac; intravenous01-12-1976US
Epinephrineinjection1 mg/mLparenteral01-07-2000US
Epinephrineinjection, solution, concentrate1 mg/mLintravenous08-08-2014US
Epinephrineinjection, solution1 mg/mLintramuscular; intravenous; subcutaneous01-03-1994US
Epinephrineinjection.1 mg/mLparenteral25-08-2010US
Epinephrineinjection1 mg/mLparenteral01-07-2000US
Epinephrineinjection, solution.1 mg/mLintracardiac; intravenous11-12-2006US
Epinephrineinjection1 mg/mLendotracheal; intracardiac; intramuscular; intravenous; subcutaneous08-05-2013US
Epinephrineinjection.15 mg/.15mLsubcutaneous01-04-2010US
Epinephrineinjection.3 mg/.3mLsubcutaneous01-04-2010US
Epinephrine 1:1000 Inj 1mg/ml USPliquid1 mgintramuscular31-12-198715-08-1997Canada
Epinephrine Inj 0.1mg/ml USPsolution0.1 mgintracardiac; intravenous31-12-1987Canada
Epinephrine Inj 0.1mg/ml USPliquid.1 mgintracardiac; intravenous31-12-198602-11-1998Canada
Epinephrine Inj 1mg/ml USPsolution1 mgintracardiac; intramuscular; intratracheal; intravenous; subcutaneous31-12-1988Canada
Epinephrine Injectionsolution1 mgintracardiac; intramuscular; intratracheal; intravenous; subcutaneous20-07-2015Canada
Epinephrine Injection USPsolution1 mgintramuscular; intravenous; subcutaneous31-12-1994Canada
Epinephrine Injection USP 1 mg/mlsolution1 mgintramuscular; intravenous; subcutaneous01-10-2010Canada
Epipeninjection.3 mg/.3mLintramuscular17-06-2003US
Epipeninjection.3 mg/.3mLintramuscular11-06-2013US
Epipensolution1 mgintramuscular31-12-1980Canada
Epipeninjection.3 mg/.3mLintramuscular22-12-1987US
Epipeninjection.3 mg/.3mLintramuscular22-12-1987US
Epipeninjection.3 mg/.3mLintramuscular22-12-1987US
Epipen Jrinjection.15 mg/.3mLintramuscular17-06-2003US
Epipen Jrinjection.15 mg/.3mLintramuscular22-12-1987US
Epipen Jrinjection.15 mg/.3mLintramuscular22-12-1987US
Epipen Jrsolution0.5 mgintramuscular31-12-1984Canada
Epipen Jrinjection.15 mg/.3mLintramuscular22-12-1987US
Episnap Epinephrine Convenience Kitinjection1 mg/1000mLintramuscular; subcutaneous01-09-2015US
KarticainesolutionArrayblock/infiltration12-04-2010Canada
Karticaine FortesolutionArrayblock/infiltration12-04-2010Canada
Lidocaineinjection, solutionArraysubcutaneous14-01-2011US
Lidocaineinjection, solutionArraysubcutaneous07-11-2011US
Lidocaineinjection, solutionArraysubcutaneous07-11-2011US
Lidocaineinjection, solutionArraysubcutaneous07-11-2011US
Lidocaineinjection, solutionArraysubcutaneous07-11-2011US
Lidocaineinjection, solutionArraysubcutaneous07-12-2011US
Lidocaineinjection, solutionArraysubcutaneous07-12-2011US
Lidocaineinjection, solutionArraysubcutaneous07-11-2011US
Lidocaineinjection, solutionArraysubcutaneous07-11-2011US
Lidocaineinjection, solutionArraysubcutaneous07-11-2011US
Lidocaineinjection, solutionArraysubcutaneous07-11-2011US
Lidocaineinjection, solutionArraysubcutaneous07-11-2011US
Lidocaineinjection, solutionArraysubcutaneous10-04-2015US
Lidocaineinjection, solutionArraysubcutaneous14-01-2011US
Lidocaine 2% and Epinephrine 1:100 000liquidArrayblock/infiltration31-12-199514-07-2008Canada
Lidocaine 2% and Epinephrine 1:100,000solutionArrayblock/infiltration15-11-2005Canada
Lidocaine 2% and Epinephrine 1:100,000 InjectionsolutionArrayblock/infiltration01-01-1970Canada
Lidocaine 2% and Epinephrine 1:50 000liquidArrayblock/infiltration31-12-199514-07-2008Canada
Lidocaine 2% and Epinephrine 1:50,000solutionArrayblock/infiltration09-01-2006Canada
Lidocaine and Epinephrine Inj.usp 2% 1:100000liquidArrayblock/infiltration31-12-1995Canada
Lidocaine HClinjection, solutionArraysubcutaneous15-05-2012US
Lidocaine Hydrochloride 0.5% and Epinephrine 1:200000 Injection USPsolutionArrayblock/infiltration01-01-1970Canada
Lidocaine Hydrochloride 1% and Epinephrine 1:100 000 Injection USPsolutionArrayblock/infiltration31-12-1989Canada
Lidocaine Hydrochloride 1.5% and Epinephrine 1:200000 Injection USPsolutionArrayblock/infiltration; epidural01-01-1970Canada
Lidocaine Hydrochloride 1.5% and Epinephrine 1:200000 Injection USP Test DosesolutionArrayblock/infiltration; epidural01-01-1970Canada
Lidocaine Hydrochloride 2% and Epinephrine 1:200000 Injection USPsolutionArrayblock/infiltration; epidural28-10-2015Canada
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration05-04-2010US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArraydental; infiltration10-02-2010US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayepidural13-09-1985US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration18-02-2014US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration05-04-2010US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArraydental; infiltration10-02-2010US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration05-07-2013US
Lidocaine Hydrochloride and EpinephrineinjectionArrayinfiltration01-08-2010US
Lidocaine Hydrochloride and EpinephrineinjectionArrayinfiltration01-08-2010US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration01-03-2010US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration05-04-2010US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration05-04-2010US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration12-07-2013US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration03-05-2010US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration03-05-2010US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration21-06-1988US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration21-06-1988US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayepidural; infiltration21-06-1988US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration21-06-1988US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayepidural; infiltration21-06-1988US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration05-04-2010US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration04-10-2013US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration05-04-2010US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration05-04-2010US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration12-06-2014US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration14-06-2014US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration05-04-2010US
Lidocaine Hydrochloride and Epinephrineinjection, solutionArrayinfiltration31-10-2013US
Lidocaine Hydrochloride and Epinephrine Bitartrateinjection, solutionArraysubcutaneous07-11-2011US
Lidocaine Hydrochloride and Epinephrine Bitartrateinjection, solutionArraysubcutaneous07-11-2011US
Lignospan ForteliquidArrayblock/infiltration31-12-1976Canada
Lignospan Forteinjection, solutionArraysubcutaneous15-10-2011US
Lignospan Speciale InjliquidArraydental; subcutaneous31-12-197803-08-2000Canada
Lignospan StandardliquidArrayblock/infiltration31-12-1976Canada
Lignospan Standardinjection, solutionArraysubcutaneous15-10-2011US
MarcainesolutionArrayblock/infiltration28-08-2008Canada
Marcaineinjection, solutionArraysubcutaneous01-06-2013US
Marcaine 0.5% and Epinephrine 1:200,000 LiqliquidArrayblock/infiltration31-12-198114-07-2008Canada
Marcaine E 0.25% Liq PrtliquidArrayblock/infiltration; epidural31-12-197310-08-2001Canada
Marcaine E 2.5 mg/mlsolutionArrayblock/infiltration; epidural15-07-2001Canada
Marcaine E 5.0 mg/mlsolutionArrayblock/infiltration; epidural15-07-2001Canada
Marcaine E Liq Prt 0.50%liquidArrayblock/infiltration; epidural31-12-197310-08-2001Canada
Marcaine With Epinephrineinjection, solutionArrayepidural; infiltration03-10-1972US
Marcaine With Epinephrineinjection, solutionArrayepidural; infiltration03-10-1972US
Marcaine With Epinephrineinjection, solutionArrayinfiltration03-10-1972US
Marcaine With Epinephrineinjection, solutionArrayinfiltration03-10-1972US
Marcaine With Epinephrineinjection, solutionArrayinfiltration06-05-2010US
Marcaine With Epinephrineinjection, solutionArrayinfiltration10-05-2010US
Numquick AnalgesicsolutionArraytopical20-01-2016US
Numquick Topical AnalgesicgelArraytopical20-01-2016US
Octocaine 100injection, solutionArraysubcutaneous07-11-2011US
Octocaine 100 Needleject InjliquidArraydental; subcutaneous31-12-198909-09-1996Canada
Octocaine 50injection, solutionArraysubcutaneous07-11-2011US
Octocaine HCl 2% Epinephrine 1:100000liquidArraysubcutaneous31-12-1964Canada
Octocaine HCl 2% Epinephrine 1:50000liquidArraysubcutaneous31-12-1964Canada
OrablocinjectionArraysubmucosal01-03-2011US
OrablocinjectionArraysubmucosal01-03-2011US
Orabloc 1:100,000solutionArrayblock/infiltration14-06-2012Canada
Orabloc 1:200,000solutionArrayblock/infiltration14-06-2012Canada
Posicaine NsolutionArrayblock/infiltration13-04-2012Canada
Posicaine SpsolutionArrayblock/infiltration13-04-2012Canada
Prilocaine HCl 4% Epineph 1:200000injliquidArrayblock/infiltration31-12-1977Canada
Prilocaine Hydrochloride With Epinephrineinjection, solutionArraysubcutaneous10-09-2011US
Scandonest 2% Special InjliquidArrayblock/infiltration31-12-1980Canada
Sensorcaineinjection, solutionArrayinfiltration; perineural19-11-2010US
Sensorcaineinjection, solutionArrayperineural19-11-2010US
Sensorcaine 0.25% With EpinephrinesolutionArrayblock/infiltration; epidural31-12-1994Canada
Sensorcaine 0.5% With EpinephrinesolutionArrayblock/infiltration; epidural31-12-1994Canada
Sensorcaine FortesolutionArrayblock/infiltration21-05-199716-04-2005Canada
Sensorcaine Mpfinjection, solutionArrayepidural; retrobulbar19-11-2010US
Sensorcaine Mpfinjection, solutionArrayepidural; intracaudal; perineural19-11-2010US
Sensorcaine Mpfinjection, solutionArrayepidural; infiltration; intracaudal; perineural19-11-2010US
Sensorcaine Mpfinjection, solutionArrayepidural; retrobulbar19-11-2010US
Septanest NliquidArrayblock/infiltration31-12-1994Canada
Septanest SpsolutionArrayblock/infiltration31-12-1994Canada
Septocaine and Epinephrineinjection, solutionArraysubcutaneous12-01-2011US
Septocaine and Epinephrineinjection, solutionArraysubcutaneous12-01-2011US
Sulpak R34/r35/r36cord.054 mgdental31-12-197722-12-1997Canada
Taro-epinephrine Auto-injectorsolution1 mgintramuscular01-01-1970Canada
Taro-epinephrine Auto-injectorsolution0.5 mgintramuscular01-01-1970Canada
Twinject 0.15mg Auto-injectorsolution0.15 mgintramuscular; subcutaneous23-08-2005Canada
Twinject 0.3mg Auto-injectorsolution0.3 mgintramuscular; subcutaneous23-08-2005Canada
Ultracaine D-S Forte InjectionsolutionArrayblock/infiltration31-12-1993Canada
Ultracaine D-S InjectionsolutionArrayblock/infiltration31-12-1994Canada
Ultracaine DS Forte InjliquidArrayblock/infiltration31-12-198129-08-1996Canada
Ultracaine DS InjliquidArrayblock/infiltration31-12-198129-08-1996Canada
Vivacaineinjection, solutionArraysubcutaneous17-12-2009US
Vivacaine (bupivacaine HCl 0.5% & Epinephrine 1:200,000 Inj, USP)solutionArrayblock/infiltration11-04-2008Canada
Xylocaineinjection, solutionArraysubcutaneous22-01-1985US
Xylocaineinjection, solutionArraysubcutaneous22-01-1985US
Xylocaineinjection, solutionArrayinfiltration; perineural15-05-1995US
Xylocaineinjection, solutionArrayinfiltration; perineural28-09-2011US
Xylocaineinjection, solutionArrayinfiltration; perineural12-09-2011US
Xylocaineinjection, solutionArrayinfiltration; perineural03-11-2011US
Xylocaineinjection, solutionArrayepidural; infiltration; intracaudal; perineural27-09-2011US
Xylocaineinjection, solutionArrayinfiltration; perineural12-08-2010US
Xylocaineinjection, solutionArrayinfiltration; perineural12-08-2010US
Xylocaineinjection, solutionArrayinfiltration; perineural12-08-2010US
Xylocaineinjection, solutionArrayinfiltration; perineural12-08-2010US
Xylocaineinjection, solutionArrayinfiltration; perineural12-08-2010US
Xylocaineinjection, solutionArrayinfiltration; perineural12-08-2010US
Xylocaineinjection, solutionArrayinfiltration; perineural12-08-2010US
Xylocaine 0.5% W Epinephrine 1:100000liquidArrayblock/infiltration31-12-195412-01-2005Canada
Xylocaine 0.5% W Epinephrine 1:200000liquidArrayblock/infiltration31-12-197102-08-2005Canada
Xylocaine 1% W Epinephrine 1:100000solutionArrayblock/infiltration31-12-1954Canada
Xylocaine 1% W Epinephrine 1:200000liquidArrayblock/infiltration31-12-1954Canada
Xylocaine 1.5% W Epinephrine 1:200000liquidArrayblock/infiltration31-12-195421-12-2011Canada
Xylocaine 1.5% W Epinephrine 1:200000 Test DoseliquidArrayepidural31-12-198820-06-2014Canada
Xylocaine 2% W Epinephrine 1:100000liquidArrayblock/infiltration31-12-195512-09-2012Canada
Xylocaine 2% W Epinephrine 1:200000liquidArrayepidural31-12-1965Canada
Xylocaine Dental Lidocaine HCl 2% and Epinephrine 1:100,000solutionArrayblock/infiltration19-10-2009Canada
Xylocaine Dental Lidocaine Hydrochloride 2% and Epinephrine 1:50,000solutionArrayblock/infiltration29-07-2010Canada
Xylocaine Mpfinjection, solutionArrayepidural; infiltration; intracaudal; perineural12-08-2010US
Xylocaine Mpfinjection, solutionArrayepidural; infiltration; intracaudal; perineural12-08-2010US
Xylocaine Mpfinjection, solutionArrayepidural; infiltration; intracaudal; perineural12-08-2010US
Xylocaine Mpfinjection, solutionArrayepidural; infiltration; intracaudal; perineural12-08-2010US
Xylocaine Mpf 1.5% With EpinephrineliquidArrayepidural31-12-199012-10-2001Canada
ZorcainesolutionArrayblock/infiltration22-04-2005Canada
Zorcaineinjection, solutionArraysubcutaneous01-09-2011US

Generic Prescription Products: Not Available
Over the Counter Products:
NameDosageStrengthRouteMarketing StartMarketing EndCountry
Prime Asthma ReliefkitArrayArray21-08-2014US
Prime Asthma Reliefcapsule.22 mg/1respiratory (inhalation)21-08-2014US

International Brands
  • No Brands

Brand Names
  • No Brands

Brand Mixtures
Brand NameIngredients
Auvi-QEpinephrine
Auvi-QEpinephrine
Octocaine 50Lidocaine + Epinephrine
VivacaineBupivacaine + Epinephrine
Prilocaine Hydrochloride With EpinephrinePrilocaine + Epinephrine
Octocaine 100Lidocaine + Epinephrine
Septocaine and EpinephrineArticaine + Epinephrine
Septocaine and EpinephrineArticaine + Epinephrine
LidocaineLidocaine + Epinephrine
LidocaineLidocaine + Epinephrine
Articaine Hydrochloride and EpinephrineArticaine + Epinephrine
Articaine Hydrochloride and EpinephrineArticaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
Marcaine With EpinephrineBupivacaine + Epinephrine
Marcaine With EpinephrineBupivacaine + Epinephrine
Marcaine With EpinephrineBupivacaine + Epinephrine
Marcaine With EpinephrineBupivacaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
EpinephrineEpinephrine
EpinephrineEpinephrine
EpinephrineEpinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
Articaine Hydrochloride and EpinephrineArticaine + Epinephrine
EpinephrineEpinephrine
EpinephrineEpinephrine
EpinephrineEpinephrine
EpinephrineEpinephrine
Prime Asthma ReliefEpinephrine
Prime Asthma ReliefEpinephrine
EpinephrineEpinephrine
Episnap Epinephrine Convenience KitEpinephrine
LidocaineLidocaine + Epinephrine
MarcaineBupivacaine + Epinephrine
ZorcaineArticaine + Epinephrine
LidocaineLidocaine + Epinephrine
AdrenalinEpinephrine
AdrenalinEpinephrine
Lidocaine Hydrochloride and Epinephrine BitartrateLidocaine + Epinephrine
ArticaineArticaine + Epinephrine
ArticaineArticaine + Epinephrine
LidocaineLidocaine + Epinephrine
Lidocaine HClLidocaine + Epinephrine
EpinephrineEpinephrine
OrablocArticaine + Epinephrine
OrablocArticaine + Epinephrine
EpipenEpinephrine
EpipenEpinephrine
Epipen JrEpinephrine
LidocaineLidocaine + Epinephrine
LidocaineLidocaine + Epinephrine
ArticaineArticaine + Epinephrine
ArticaineArticaine + Epinephrine
LidocaineLidocaine + Epinephrine
LidocaineLidocaine + Epinephrine
Lignospan StandardLidocaine + Epinephrine
Lignospan ForteLidocaine + Epinephrine
Lidocaine Hydrochloride and Epinephrine BitartrateLidocaine + Epinephrine
AdrenaclickEpinephrine
AdrenaclickEpinephrine
Lidocaine Hydrochloride and EpinephrineEpinephrine + Lidocaine
Lidocaine Hydrochloride and EpinephrineEpinephrine + Lidocaine
Lidocaine Hydrochloride and EpinephrineEpinephrine + Lidocaine
Lidocaine Hydrochloride and EpinephrineEpinephrine + Lidocaine
EpinephrineEpinephrine
Lidocaine Hydrochloride and EpinephrineEpinephrine + Lidocaine
EphinephrineEpinephrine
EpinephrineEpinephrine
EpinephrineEpinephrine
Bupivacaine Hydrochloride and EpinephrineBupivacaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
EpinephrineEpinephrine
XylocaineLidocaine + Epinephrine
XylocaineLidocaine + Epinephrine
XylocaineLidocaine + Epinephrine
XylocaineLidocaine + Epinephrine
EpinephrineEpinephrine
EpinephrineEpinephrine
EpinephrineEpinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
XylocaineLidocaine + Epinephrine
EpipenEpinephrine
Marcaine With EpinephrineBupivacaine + Epinephrine
Marcaine With EpinephrineBupivacaine + Epinephrine
Epipen JrEpinephrine
EpinephrineEpinephrine
EpinephrineEpinephrine
EpipenEpinephrine
Epipen JrEpinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
EpinephrineEpinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
EpinephrineEpinephrine
EpinephrineEpinephrine
Bupivacaine Hydrochloride and EpinephrineBupivacaine + Epinephrine
Bupivacaine Hydrochloride and EpinephrineBupivacaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
Sensorcaine MpfBupivacaine + Epinephrine
XylocaineLidocaine + Epinephrine
XylocaineLidocaine + Epinephrine
XylocaineLidocaine + Epinephrine
Xylocaine MpfLidocaine + Epinephrine
XylocaineLidocaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
AdrenalinEpinephrine
EpinephrineEpinephrine
Sensorcaine MpfBupivacaine + Epinephrine
SensorcaineBupivacaine + Epinephrine
Sensorcaine MpfBupivacaine + Epinephrine
SensorcaineBupivacaine + Epinephrine
Sensorcaine MpfBupivacaine + Epinephrine
XylocaineLidocaine + Epinephrine
XylocaineLidocaine + Epinephrine
XylocaineLidocaine + Epinephrine
Xylocaine MpfLidocaine + Epinephrine
Xylocaine MpfLidocaine + Epinephrine
Xylocaine MpfLidocaine + Epinephrine
EpinephrineEpinephrine
EpinephrineEpinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
Lidocaine Hydrochloride and EpinephrineLidocaine + Epinephrine
EpipenEpinephrine
Epipen JrEpinephrine
XylocaineLidocaine + Epinephrine
XylocaineLidocaine + Epinephrine
Citanest FortePrilocaine + Epinephrine
ArticadentArticaine + Epinephrine
ArticadentArticaine + Epinephrine
LidocaineLidocaine + Epinephrine
LidocaineLidocaine + Epinephrine
LidocaineLidocaine + Epinephrine
LidocaineLidocaine + Epinephrine
LidocaineLidocaine + Epinephrine
EpinephrineEpinephrine
EpinephrineEpinephrine
Adrenalin Chloride Sol 1:1000Epinephrine
Sensorcaine 0.25% With EpinephrineBupivacaine + Epinephrine
Sensorcaine 0.5% With EpinephrineBupivacaine + Epinephrine
Ultracaine D-S InjectionArticaine + Epinephrine
Ultracaine D-S Forte InjectionArticaine + Epinephrine
Septanest SpArticaine + Epinephrine
Septanest NArticaine + Epinephrine
Epinephrine Injection USPEpinephrine
Lidocaine and Epinephrine Inj.usp 2% 1:100000Lidocaine + Epinephrine
Xylocaine 2% W Epinephrine 1:200000Lidocaine + Epinephrine
Lignospan ForteLidocaine + Epinephrine
Lignospan StandardLidocaine + Epinephrine
Prilocaine HCl 4% Epineph 1:200000injEpinephrine + Prilocaine
Scandonest 2% Special InjMepivacaine + Epinephrine
EpipenEpinephrine
Xylocaine 1% W Epinephrine 1:100000Lidocaine + Epinephrine
Xylocaine 1% W Epinephrine 1:200000Lidocaine + Epinephrine
Epipen JrEpinephrine
Octocaine HCl 2% Epinephrine 1:50000Lidocaine + Epinephrine
Octocaine HCl 2% Epinephrine 1:100000Lidocaine + Epinephrine
Marcaine E 2.5 mg/mlBupivacaine + Epinephrine
Marcaine E 5.0 mg/mlBupivacaine + Epinephrine
Twinject 0.3mg Auto-injectorEpinephrine
4% Astracaine Dental With Epinephrine Forte 1:100,000 (0.01mg/ml)Articaine + Epinephrine
4% Astracaine Dental With Epinephrine 1:200,000 (0.005mg/ml)Articaine + Epinephrine
ZorcaineArticaine + Epinephrine
Twinject 0.15mg Auto-injectorEpinephrine
Lidocaine 2% and Epinephrine 1:100,000Lidocaine + Epinephrine
Lidocaine 2% and Epinephrine 1:50,000Lidocaine + Epinephrine
2% Lidocaine and Epinephrine 1:100,000 Injection USPLidocaine + Epinephrine
Vivacaine (bupivacaine HCl 0.5% & Epinephrine 1:200,000 Inj, USP)Bupivacaine + Epinephrine
Anapen JuniorEpinephrine
AnapenEpinephrine
MarcaineBupivacaine + Epinephrine
Epinephrine Injection USP 1 mg/mlEpinephrine
Xylocaine Dental Lidocaine HCl 2% and Epinephrine 1:100,000Lidocaine + Epinephrine
KarticaineArticaine + Epinephrine
Karticaine ForteArticaine + Epinephrine
Xylocaine Dental Lidocaine Hydrochloride 2% and Epinephrine 1:50,000Lidocaine + Epinephrine
4% Citanest Forte Dental With Epinephrine 1:200,000Epinephrine + Prilocaine
Epinephrine Inj 0.1mg/ml USPEpinephrine
Orabloc 1:200,000Articaine + Epinephrine
Orabloc 1:100,000Articaine + Epinephrine
Posicaine NArticaine + Epinephrine
Posicaine SpArticaine + Epinephrine
Bupivacaine HCl 0.5% and Epinephrine 1:200,000 InjectionBupivacaine + Epinephrine
AllerjectEpinephrine
AllerjectEpinephrine
Adrenalin Chloride Sol 1:1000 AmpEpinephrine
Octocaine 100 Needleject InjLidocaine + Epinephrine
Xylocaine Mpf 1.5% With EpinephrineLidocaine + Epinephrine
Xylocaine 0.5% W Epinephrine 1:200000Lidocaine + Epinephrine
Bronkaid Mistometer Aem 0.5%Epinephrine
Marcaine E Liq Prt 0.50%Bupivacaine + Epinephrine
Marcaine E 0.25% Liq PrtBupivacaine + Epinephrine
Lidocaine 2% and Epinephrine 1:50 000Lidocaine + Epinephrine
Lidocaine 2% and Epinephrine 1:100 000Lidocaine + Epinephrine
E-pilo 4 Ophthalmic SolutionPilocarpine + Epinephrine
Marcaine 0.5% and Epinephrine 1:200,000 LiqBupivacaine + Epinephrine
E-pilo 1 Ophthalmic SolutionPilocarpine + Epinephrine
Anakit Insect Sting Treatment KitChlorphenamine + Epinephrine
Sulpak R34/r35/r36Epinephrine
E-pilo 2 Ophthalmic SolutionPilocarpine + Epinephrine
E-pilo 6 Ophthalmic SolutionPilocarpine + Epinephrine
Lignospan Speciale InjLidocaine + Epinephrine
Ana-kit (2mg/tab Orl, 1mg/ml Liq Sc Im)Chlorphenamine + Epinephrine
Epi E-Z Pen - Liquid - 0.3mg/0.3mlEpinephrine
Dentsply 4% Prilocaine and Epinephrine Injection 1:200,000Epinephrine + Prilocaine
Ultracaine DS InjArticaine + Epinephrine
Ultracaine DS Forte InjArticaine + Epinephrine
Sensorcaine ForteBupivacaine + Epinephrine
4% Astracaine Dental With Epinephrine Forte 1:100,000 (0.01mg/ml)Articaine + Epinephrine
4% Astracaine Dental With Epinephrine 1:200,000 (0.005mg/ml)Articaine + Epinephrine
Xylocaine 0.5% W Epinephrine 1:100000Lidocaine + Epinephrine
Xylocaine 1.5% W Epinephrine 1:200000Lidocaine + Epinephrine
Xylocaine 2% W Epinephrine 1:100000Lidocaine + Epinephrine
Dentsply 2% Lidocaine With Epinephrine 1:50,000Lidocaine + Epinephrine
Dentsply 2% Lidocaine With Epinephrine 1:100,000Lidocaine + Epinephrine
Epinephrine Inj 0.1mg/ml USPEpinephrine
Epinephrine 1:1000 Inj 1mg/ml USPEpinephrine
E-pilo-2 Oph SolnPilocarpine + Epinephrine
E-pilo-6 Oph SolnPilocarpine + Epinephrine
E-pilo-4 Oph SolnPilocarpine + Epinephrine
E-pilo-1 Oph SolnPilocarpine + Epinephrine
Xylocaine 1.5% W Epinephrine 1:200000 Test DoseLidocaine + Epinephrine
Adrenaclick 0.15mg Auto-injectorEpinephrine
Adrenaclick 0.30mg Auto-injectorEpinephrine
Taro-epinephrine Auto-injectorEpinephrine
Taro-epinephrine Auto-injectorEpinephrine
Lidocaine 2% and Epinephrine 1:100,000 InjectionLidocaine + Epinephrine
Lidocaine Hydrochloride 1% and Epinephrine 1:100 000 Injection USPLidocaine + Epinephrine
Lidocaine Hydrochloride 0.5% and Epinephrine 1:200000 Injection USPLidocaine + Epinephrine
Lidocaine Hydrochloride 1.5% and Epinephrine 1:200000 Injection USP Test DoseLidocaine + Epinephrine
Epinephrine Inj 1mg/ml USPEpinephrine
Epinephrine InjectionEpinephrine
Lidocaine Hydrochloride 2% and Epinephrine 1:200000 Injection USPLidocaine + Epinephrine
Lidocaine Hydrochloride 1.5% and Epinephrine 1:200000 Injection USPLidocaine + Epinephrine
Numquick Topical AnalgesicEpinephrine + Lidocaine
Numquick AnalgesicEpinephrine + Lidocaine
Bupivacaine Hydrochloride and EpinephrineBupivacaine + Epinephrine
Bupivacaine Hydrochloride and EpinephrineBupivacaine + Epinephrine
Bupivacaine Hydrochloride and EpinephrineBupivacaine + Epinephrine
Bupivacaine Hydrochloride and EpinephrineBupivacaine + Epinephrine
Bupivacaine Hydrochloride and EpinephrineBupivacaine + Epinephrine

Categories
  • Vasoconstrictor Agents
  • Sympathomimetics
  • Bronchodilator Agents
  • Adrenergic alpha-Agonists
  • Mydriatics
  • Adrenergic beta-Agonists

Pharmacology

Indication: Used to treat anaphylaxis and sepsis. Also one of the body's main adrenergic neurotransmitters.
Pharmacodynamics: Not Available
Mechanism of action: Epinephrine works via the stimulation of alpha and beta-1 adrenergic receptors, and a moderate activity at beta-2 adrenergic receptors.
Absorption: Usually this vasodilator effect of the drug on the circulation predominates so that the modest rise in systolic pressure which follows slow injection or absorption is mainly the result of direct cardiac stimulation and increase in cardiac output.
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Renal
Half life: 2 minutes
Clearance: Not Available
Toxicity: Skin, LD50 = 62 mg/kg (rat)
Affected organisms
  • Not Available

SNP Mediated Adverse Drug Reactions
  • Not Available

Pharmacoeconomics

Manufacturers:
  • Sterling health div sterling winthrop inc
  • Armstrong pharmaceuticals inc
  • Wyeth consumer healthcare
  • Shionogi pharma inc
  • Meridian medical technologies inc
  • Forest laboratories inc
  • 3m pharmaceuticals inc
  • Astrazeneca lp
  • Pharmaton ltd
  • Dentsply pharmaceutical

Packagers:
Dosage forms
FormRouteStrength
Injectionsubcutaneous.15 mg/.15mL
Injectionsubcutaneous.3 mg/.3mL
Solutionintramuscular0.30 mg
Injectionintramuscular1 mg/mL
Injectionintramuscular; intraocular; subcutaneous1 mg/mL
Injectionintramuscular; subcutaneous1 mg/mL
Solutionnasal1 mg
Liquid; tabletintramuscular; oral; subcutaneous
Liquid; tabletoral; parenteral (unspecified)
Solutionintramuscular0.3 mg
Solutionintramuscular0.15 mg
Injectionintramuscular; subcutaneous.15 mg/1
Injectionintramuscular; subcutaneous.3 mg/1
Metered-dose aerosolinhalation0.5 %
Injectionepidural; infiltration; intracaudal
Injection, solutionepidural; infiltration; intracaudal
Injection, solutionepidural; intracaudal
Injection, solutiondental
Dropsophthalmic
Injection, solutionintravenous.1 mg/mL
Liquidintramuscular0.3 mg
Injectionendotracheal; intracardiac; intramuscular; intravenous; subcutaneous1 mg/mL
Injectionintracardiac; intravenous.1 mg/mL
Injectionparenteral.1 mg/mL
Injectionparenteral1 mg/mL
Injectionsubcutaneous.3 mg/1
Injection, solutionendotracheal; intracardiac; intravenous.1 mg/mL
Injection, solutionintracardiac; intramuscular; intravenous; subcutaneous1 mg/mL
Injection, solutionintracardiac; intravenous.1 mg/mL
Injection, solutionintramuscular; intravenous; subcutaneous1 mg/mL
Injection, solutionintramuscular; subcutaneous1 mg/mL
Injection, solutionsubcutaneous1 mg/mL
Injection, solution, concentrateintravenous1 mg/mL
Liquidintramuscular1 mg
Liquidintracardiac; intravenous.1 mg
Solutionintracardiac; intravenous0.1 mg
Solutionintracardiac; intramuscular; intratracheal; intravenous; subcutaneous1 mg
Solutionintramuscular; intravenous; subcutaneous1 mg
Injectionintramuscular.3 mg/.3mL
Solutionintramuscular1 mg
Injectionintramuscular.15 mg/.3mL
Solutionintramuscular0.5 mg
Injectionintramuscular; subcutaneous1 mg/1000mL
Injectioninfiltration
Injection, solutiondental; infiltration
Injection, solutionepidural
Liquidblock/infiltration; epidural
Injection, solutionepidural; infiltration
Injection, solutioninfiltration
Solutiontopical
Geltopical
Liquiddental; subcutaneous
Injection, solutionsubcutaneous
Liquidsubcutaneous
Injectionsubmucosal
Capsulerespiratory (inhalation).22 mg/1
Kit
Injection, solutionperineural
Solutionblock/infiltration; epidural
Injection, solutionepidural; intracaudal; perineural
Injection, solutionepidural; retrobulbar
Liquidblock/infiltration
Corddental.054 mg
Solutionintramuscular; subcutaneous0.15 mg
Solutionintramuscular; subcutaneous0.3 mg
Solutionblock/infiltration
Injection, solutionepidural; infiltration; intracaudal; perineural
Injection, solutioninfiltration; perineural
Liquidepidural

Prices
Unit descriptionCostUnit
Primatene mist inhaler$1.0ml
Epinephrine 0.1 mg/ml syringe$1.32ml
Adrenalin cl 1 mg/ml vial$1.42ml
Epinephrine 1 mg/ml ampul$2.9ml
Adrenalin 1 mg/ml ampul$2.93ml
Epinephrine bitartrate crys$4.2g
Epinephrine powder$4.68g
Epipen 0.3 mg auto-injector$41.78each
Nephron FA 100 tablet Box$49.99box
Epinephrine 0.3 mg auto-inject$67.05each
Epipen jr 0.15 mg auto-inject$74.58each
EpiPen (single Syringe) Syringe$77.56syringe
EpiPen Jr (single Syringe) Syringe$77.56syringe
Twinject Auto Injector 0.15 mg/syr Syringe$84.85syringe
Twinject Auto Injector 0.3 mg/syr Syringe$84.85syringe
Twinject 0.15 mg auto-injector$86.63each
Epipen 0.3 mg/syr Syringe$93.04syringe
Epipen Jr 0.15 mg/syr Syringe$93.04syringe
Twinject 0.15 mg/dose Device Syringe$104.14syringe
EpiPen 2-Pak (1 Package = 2 Syringes) Package$155.13package
EpiPen Jr 2-Pak (1 Package = 2 Syringes) Package$155.13package
Epinephrine hcl powder$189.0g
Twinject 2 0.3 mg/dose Device One Box Contains 2 Syringes$200.43box
Epinephrine-d5w 2 mg/250 ml$0.07ml
Bronkaid dual action caplet$0.14caplet
Epinephrine 1 mg/ml vial$0.18ml
Nephron fa tablet$0.44each
Adrenalin 1 mg/ml Solution$0.61ml
Adrenalin 1 mg/ml$0.62ml
Primatene mist inh refill$0.68ml
Bronchial mist inhaler$0.8ml
Adrenalin 1:1000 nasal soln$0.83ml

Patents
CountryPatent NumberApprovedExpires (estimated)
5665071United States1993-05-272013-05-27
7449012United States2005-09-112025-09-11

Interactions

Drug Interactions
DrugInteraction
AcebutololThe risk or severity of adverse effects can be increased when Acebutolol is combined with Epinephrine.
AcetaminophenThe risk or severity of adverse effects can be increased when Epinephrine is combined with Acetaminophen.
AcetohexamideThe therapeutic efficacy of Acetohexamide can be decreased when used in combination with Epinephrine.
Acetylsalicylic acidThe risk or severity of adverse effects can be increased when Epinephrine is combined with Acetylsalicylic acid.
AlfuzosinAlfuzosin may decrease the vasoconstricting activities of Epinephrine.
AlogliptinThe therapeutic efficacy of Alogliptin can be decreased when used in combination with Epinephrine.
AminophyllineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Aminophylline.
AmitriptylineAmitriptyline may increase the activities of Epinephrine.
AmphetamineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Amphetamine.
ArformoterolThe risk or severity of adverse effects can be increased when Epinephrine is combined with Arformoterol.
ArmodafinilThe risk or severity of adverse effects can be increased when Epinephrine is combined with Armodafinil.
ArticaineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Articaine.
AtomoxetineAtomoxetine may increase the hypertensive activities of Epinephrine.
BenzphetamineThe risk or severity of adverse effects can be increased when Benzphetamine is combined with Epinephrine.
Benzylpenicilloyl PolylysineEpinephrine may decrease effectiveness of Benzylpenicilloyl Polylysine as a diagnostic agent.
ButalbitalThe risk or severity of adverse effects can be increased when Epinephrine is combined with Butalbital.
CabergolineCabergoline may increase the hypertensive activities of Epinephrine.
CaffeineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Caffeine.
CanagliflozinThe therapeutic efficacy of Canagliflozin can be decreased when used in combination with Epinephrine.
ChlorphentermineThe risk or severity of adverse effects can be increased when Chlorphentermine is combined with Epinephrine.
ChlorpropamideThe therapeutic efficacy of Chlorpropamide can be decreased when used in combination with Epinephrine.
ClenbuterolThe risk or severity of adverse effects can be increased when Clenbuterol is combined with Epinephrine.
CocaineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Cocaine.
DesfluraneDesflurane may increase the arrhythmogenic activities of Epinephrine.
DexmethylphenidateThe risk or severity of adverse effects can be increased when Epinephrine is combined with Dexmethylphenidate.
DextroamphetamineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Dextroamphetamine.
DiethylpropionThe risk or severity of adverse effects can be increased when Epinephrine is combined with Diethylpropion.
DihydrocodeineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Dihydrocodeine.
DipivefrinThe risk or severity of adverse effects can be increased when Epinephrine is combined with Dipivefrin.
DobutamineThe risk or severity of adverse effects can be increased when Dobutamine is combined with Epinephrine.
DopamineThe risk or severity of adverse effects can be increased when Dopamine is combined with Epinephrine.
DoxapramThe risk or severity of adverse effects can be increased when Epinephrine is combined with Doxapram.
DoxofyllineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Doxofylline.
DronabinolDronabinol may increase the tachycardic activities of Epinephrine.
DyphyllineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Dyphylline.
EphedrineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Ephedrine.
FenoterolThe risk or severity of adverse effects can be increased when Fenoterol is combined with Epinephrine.
Fluticasone PropionateThe risk or severity of adverse effects can be increased when Epinephrine is combined with Fluticasone Propionate.
FormoterolThe risk or severity of adverse effects can be increased when Formoterol is combined with Epinephrine.
GliclazideThe therapeutic efficacy of Gliclazide can be decreased when used in combination with Epinephrine.
GlimepirideThe therapeutic efficacy of Glimepiride can be decreased when used in combination with Epinephrine.
GliquidoneThe therapeutic efficacy of Gliquidone can be decreased when used in combination with Epinephrine.
GlyburideThe therapeutic efficacy of Glyburide can be decreased when used in combination with Epinephrine.
HyaluronidaseHyaluronidase may increase the vasoconstricting activities of Epinephrine.
IndacaterolThe risk or severity of adverse effects can be increased when Epinephrine is combined with Indacaterol.
Insulin AspartThe therapeutic efficacy of Insulin Aspart can be decreased when used in combination with Epinephrine.
Insulin DetemirThe therapeutic efficacy of Insulin Detemir can be decreased when used in combination with Epinephrine.
Insulin GlargineThe therapeutic efficacy of Insulin Glargine can be decreased when used in combination with Epinephrine.
Insulin GlulisineThe therapeutic efficacy of Insulin Glulisine can be decreased when used in combination with Epinephrine.
Insulin LisproThe therapeutic efficacy of Insulin Lispro can be decreased when used in combination with Epinephrine.
Insulin RegularThe therapeutic efficacy of Insulin Regular can be decreased when used in combination with Epinephrine.
Insulin, isophaneThe therapeutic efficacy of Insulin, isophane can be decreased when used in combination with Epinephrine.
IobenguaneThe therapeutic efficacy of Iobenguane can be decreased when used in combination with Epinephrine.
Ipratropium bromideThe risk or severity of adverse effects can be increased when Epinephrine is combined with Ipratropium bromide.
IsocarboxazidIsocarboxazid may increase the hypertensive activities of Epinephrine.
IsofluraneIsoflurane may increase the arrhythmogenic activities of Epinephrine.
IsomethepteneThe risk or severity of adverse effects can be increased when Epinephrine is combined with Isometheptene.
IsoprenalineThe risk or severity of adverse effects can be increased when Isoprenaline is combined with Epinephrine.
LabetalolThe risk or severity of adverse effects can be increased when Labetalol is combined with Epinephrine.
LevonordefrinThe risk or severity of adverse effects can be increased when Epinephrine is combined with Levonordefrin.
LinagliptinThe therapeutic efficacy of Linagliptin can be decreased when used in combination with Epinephrine.
LinezolidLinezolid may increase the hypertensive activities of Epinephrine.
LisdexamfetamineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Lisdexamfetamine.
LurasidoneEpinephrine may increase the hypotensive activities of Lurasidone.
MephentermineThe risk or severity of adverse effects can be increased when Mephentermine is combined with Epinephrine.
MepivacaineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Mepivacaine.
MetaraminolThe risk or severity of adverse effects can be increased when Metaraminol is combined with Epinephrine.
MetforminThe therapeutic efficacy of Metformin can be decreased when used in combination with Epinephrine.
MethamphetamineThe risk or severity of adverse effects can be increased when Methamphetamine is combined with Epinephrine.
MethoxamineThe risk or severity of adverse effects can be increased when Methoxamine is combined with Epinephrine.
MethylphenidateThe risk or severity of adverse effects can be increased when Epinephrine is combined with Methylphenidate.
MidodrineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Midodrine.
MoclobemideMoclobemide may increase the hypertensive activities of Epinephrine.
ModafinilThe risk or severity of adverse effects can be increased when Epinephrine is combined with Modafinil.
NabiloneNabilone may increase the tachycardic activities of Epinephrine.
NadololNadolol may increase the activities of Epinephrine.
NaphazolineThe risk or severity of adverse effects can be increased when Naphazoline is combined with Epinephrine.
NorepinephrineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Norepinephrine.
OlodaterolThe risk or severity of adverse effects can be increased when Epinephrine is combined with Olodaterol.
OrciprenalineThe risk or severity of adverse effects can be increased when Orciprenaline is combined with Epinephrine.
OxymetazolineThe risk or severity of adverse effects can be increased when Oxymetazoline is combined with Epinephrine.
PhendimetrazineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Phendimetrazine.
PhenelzinePhenelzine may increase the hypertensive activities of Epinephrine.
PheniramineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Pheniramine.
PhenmetrazineThe risk or severity of adverse effects can be increased when Phenmetrazine is combined with Epinephrine.
PhentermineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Phentermine.
PhenylephrineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Phenylephrine.
PhenylpropanolamineThe risk or severity of adverse effects can be increased when Phenylpropanolamine is combined with Epinephrine.
PirbuterolThe risk or severity of adverse effects can be increased when Epinephrine is combined with Pirbuterol.
PrazosinPrazosin may decrease the vasoconstricting activities of Epinephrine.
ProcarbazineProcarbazine may increase the hypertensive activities of Epinephrine.
PromethazinePromethazine may decrease the vasoconstricting activities of Epinephrine.
PropylhexedrineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Propylhexedrine.
PseudoephedrineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Pseudoephedrine.
RacepinephrineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Racepinephrine.
RasagilineRasagiline may increase the hypertensive activities of Epinephrine.
RepaglinideThe therapeutic efficacy of Repaglinide can be decreased when used in combination with Epinephrine.
RitodrineThe risk or severity of adverse effects can be increased when Ritodrine is combined with Epinephrine.
SalbutamolThe risk or severity of adverse effects can be increased when Epinephrine is combined with Salbutamol.
SalmeterolThe risk or severity of adverse effects can be increased when Salmeterol is combined with Epinephrine.
SaxagliptinThe therapeutic efficacy of Saxagliptin can be decreased when used in combination with Epinephrine.
SelegilineSelegiline may increase the hypertensive activities of Epinephrine.
SevofluraneSevoflurane may increase the arrhythmogenic activities of Epinephrine.
SpironolactoneSpironolactone may decrease the vasoconstricting activities of Epinephrine.
Technetium Tc-99m tilmanoceptEpinephrine may decrease effectiveness of Technetium Tc-99m tilmanocept as a diagnostic agent.
Tedizolid PhosphateTedizolid Phosphate may increase the hypertensive activities of Epinephrine.
TerbutalineThe risk or severity of adverse effects can be increased when Terbutaline is combined with Epinephrine.
TheophyllineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Theophylline.
TolbutamideThe therapeutic efficacy of Tolbutamide can be decreased when used in combination with Epinephrine.
TolcaponeThe metabolism of Epinephrine can be decreased when combined with Tolcapone.
TranylcypromineTranylcypromine may increase the hypertensive activities of Epinephrine.
TriprolidineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Triprolidine.
VenlafaxineVenlafaxine may increase the tachycardic activities of Epinephrine.
VilanterolThe risk or severity of adverse effects can be increased when Epinephrine is combined with Vilanterol.
VildagliptinThe therapeutic efficacy of Vildagliptin can be decreased when used in combination with Epinephrine.

Food Interactions:
  • Not Available

Taxonomy

Kingdom: Organic compounds
Super Class: Not Available
Class: Not Available
Sub Class: Not Available
Direct Parent: Not Available
Alternative Parents:
  • 1,2-aminoalcohols
  • Aralkylamines
  • Aromatic alcohols
  • Dialkylamines
  • Hydrocarbon derivatives
  • Secondary alcohols

substituent:
  • 1,2-aminoalcohol
  • Alcohol
  • Amine
  • Aralkylamine
  • Aromatic alcohol
  • Aromatic homomonocyclic compound
  • Catecholamine
  • Hydrocarbon derivative
  • Organonitrogen compound
  • Organooxygen compound
  • Secondary alcohol
  • Secondary aliphatic amine
  • Secondary amine

References

Synthesis Reference: Pamela Albaugh, "Pharmaceutical epinephrine-pilocarpine compounds and process of preparation thereof." U.S. Patent US5198545, issued October, 1988.
General Reference: # Yamashima T: Jokichi Takamine (1854-1922), the samurai chemist, and his work on adrenalin. J Med Biogr. 2003 May;11(2):95-102. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/12717538 # Bennett MR: One hundred years of adrenaline: the discovery of autoreceptors. Clin Auton Res. 1999 Jun;9(3):145-59. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10454061
External Links:
ResourceLink
RxListhttp://www.rxlist.com/cgi/generic/epi.htm
Drugs.comhttp://www.drugs.com/mtm/epinephrine-ophthalmic.html

ATC Codes:
  • Array
  • Array
  • Array
  • Array
  • Array
  • Array

AHFS Codes:
  • 12:12.12
  • 52:24.00
  • 52:32.00
  • 92:02.00*

MSDS: Download

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The Purple Society, Purple Gladiator, Trialsmap, The Purple Drug Guide, and One Person CAN Make A Difference! are all registered trademarks of The Purple Society.
The Purple Society, a not-for-profit, section 501(c)(3) 
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The Purple Society website is designed for educational purposes only and is not engaged in rendering medical advice or professional services. The information provided through this site should not be used for diagnosing or treating a health problem or a disease. It is not a substitute for professional care. If you have or suspect you may have a health problem, you should consult your health care provider.

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